KEGG   ENZYME: 2.7.1.86Help
Entry
EC 2.7.1.86                 Enzyme                                 

Name
NADH kinase;
reduced nicotinamide adenine dinucleotide kinase (phosphorylating);
DPNH kinase;
reduced diphosphopyridine nucleotide kinase;
NADH kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:NADH 2'-phosphotransferase
Reaction(IUBMB)
ATP + NADH = ADP + NADPH [RN:R00105]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
NADH [CPD:C00004]
Product
ADP [CPD:C00008];
NADPH [CPD:C00005]
Comment
CTP, ITP, UTP and GTP can also act as phosphate donors (in decreasing order of activity). The enzyme is specific for NADH. Activated by acetate.
History
EC 2.7.1.86 created 1976 (EC 2.7.1.96 created 1978, incorporated 1978)
Orthology
K19386  NADH kinase
Genes
SCE: YPL188W(POS5)
AGO: AGOS_AFL063W
ERC: Ecym_2231
KLA: KLLA0_E19097g
KMX: KLMA_60357(POS5)
LTH: KLTH0H04818g
VPO: Kpol_1002p66
ZRO: ZYRO0G08206g
CGR: CAGL0G02893g
NCS: NCAS_0H01000(NCAS0H01000)
NDI: NDAI_0F02290(NDAI0F02290)
TPF: TPHA_0J02240(TPHA0J02240)
TBL: TBLA_0B05170(TBLA0B05170)
TDL: TDEL_0G01590(TDEL0G01590)
KAF: KAFR_0B06770(KAFR0B06770)
PIC: PICST_53028(POS5)
CAL: CAALFM_C307010WA(POS5)
CAUR: QG37_06893
NCR: NCU07742
NTE: NEUTE1DRAFT128131(NEUTE1DRAFT_128131)
MGR: MGG_05450
SSCK: SPSK_07486
MAW: MAC_05584
MAJ: MAA_05021
CMT: CCM_04929
BFU: BCIN_10g02880(Bcpos5)
MBE: MBM_01005
ANI: AN8837.2
ANG: ANI_1_502154(An17g02020)
ABE: ARB_07009
TVE: TRV_06453
PTE: PTT_12200
SPO: SPAC323.01c(pos5)
CNE: CNC04760
CNB: CNBC2410
ABP: AGABI1DRAFT99179(AGABI1DRAFT_99179)
ABV: AGABI2DRAFT178464(AGABI2DRAFT_178464)
MGL: MGL_0521
 » show all
Taxonomy
Reference
1  [PMID:4335000]
  Authors
Griffiths MM, Bernofsky C.
  Title
Purification and properties of reduced diphosphopyridine nucleotide kinase from yeast mitochondria.
  Journal
J Biol Chem 247:1473-8 (1972)
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.86
IUBMB Enzyme Nomenclature: 2.7.1.86
ExPASy - ENZYME nomenclature database: 2.7.1.86
BRENDA, the Enzyme Database: 2.7.1.86
CAS: 62213-39-2

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