KEGG   ENZYME: 2.7.11.32Help
Entry
EC 2.7.11.32                Enzyme                                 

Name
[pyruvate, phosphate dikinase] kinase;
PPDK regulatory protein (ambiguous);
pyruvate;
phosphate dikinase regulatory protein (ambiguous);
bifunctional dikinase regulatory protein (ambiguous)
Class
Transferases;
Transferring phosphorus-containing groups;
Protein-serine/threonine kinases
BRITE hierarchy
Sysname
ADP:[pyruvate, phosphate dikinase] phosphotransferase
Reaction(IUBMB)
ADP + [pyruvate, phosphate dikinase] = AMP + [pyruvate, phosphate dikinase] phosphate
Substrate
ADP [CPD:C00008];
[pyruvate, phosphate dikinase]
Product
AMP [CPD:C00020];
[pyruvate, phosphate dikinase] phosphate
Comment
The enzymes from the plants Zea mays (maize) and Arabidopsis thaliana are bifunctional and catalyse both the phosphorylation and dephosphorylation of EC 2.7.9.1 (pyruvate, phosphate dikinase). cf. EC 2.7.4.27, [pyruvate, phosphate dikinase]-phosphate phosphotransferase [2-5]. The enzyme is specific for a reaction intermediate form of EC 2.7.9.1, and phosphorylates a threonine located adjacent to the catalytic histidine. The phosphorylation only takes place if the histidine is already phosphorylated [3-5].
History
EC 2.7.11.32 created 2012
Orthology
K20115  [pyruvate, phosphate dikinase]-phosphate phosphotransferase / [pyruvate, phosphate dikinase] kinase
Genes
ATH: AT3G01200(RP2) AT4G21210(RP1)
ALY: ARALYDRAFT_477409 ARALYDRAFT_492762
CRB: 17878882 17892435
CSAT: 104698933 104718210 104722939 104731423 104744240 104763839
EUS: EUTSA_v10020923mg EUTSA_v10025354mg
BRP: 103842753 103858872 103870958
BNA: 106345705 106404071 106406424 106435635 106438335 106440302
BOE: 106293872 106296714 106341208 106342598
THJ: 104812524 104821035
CPAP: 110806752 110806754
CIT: 102625399
TCC: 18597088
GRA: 105773645
DZI: 111318795
EGR: 104441127
VAR: 108326098
CCAJ: 109794396
CAM: 101507702
LJA: Lj5g3v2060750.1(Lj5g3v2060750.1)
ADU: 107467154
AIP: 107617832
LANG: 109336124
FVE: 101308056
PPER: 18780113
PMUM: 103324490
PAVI: 110763034
ZJU: 107421062
CSV: 101220007
CMO: 103485569
MCHA: 111010787
CMAX: 111495454
CMOS: 111440043
CPEP: 111782979
RCU: 8267381
JCU: 105649393
HBR: 110636619
POP: 7458550
JRE: 108983234
VVI: 100267490
SLY: 101255037
SPEN: 107002608
SOT: 102594017
CANN: 107845493
NSY: 104225429
NTO: 104109587
INI: 109165297
SIND: 105167965
OEU: 111396000
DCR: 108209066
BVG: 104901122
SOE: 110799056
OSA: 4343450
DOSA: Os07t0530600-01(Os07g0530600)
OBR: 102710420
BDI: 100839068
ATS: 109748005(LOC109748005)
ZMA: 100279565 732785(pco142971)
SITA: 101777229
MUS: 103986573
DCT: 110106594
AOF: 109833321
ATR: 18440240
PPP: 112288144
SMIN: v1.2.014430.t1(symbB.v1.2.014430.t1) v1.2.022569.t1(symbB.v1.2.022569.t1) v1.2.027162.t1(symbB.v1.2.027162.t1) v1.2.028672.t1(symbB.v1.2.028672.t1) v1.2.040824.t3(symbB.v1.2.040824.t3)
 » show all
Taxonomy
Reference
1  [PMID:6326674]
  Authors
Burnell JN, Hatch MD
  Title
Regulation of C4 photosynthesis: identification of a catalytically important histidine residue and its role in the regulation of pyruvate,Pi dikinase.
  Journal
Arch Biochem Biophys 231:175-82 (1984)
DOI:10.1016/0003-9861(84)90375-8
  Sequence
[zma:732785]
Reference
2  [PMID:2983615]
  Authors
Burnell JN, Hatch MD
  Title
Regulation of C4 photosynthesis: purification and properties of the protein catalyzing ADP-mediated inactivation and Pi-mediated activation of pyruvate,Pi dikinase.
  Journal
Arch Biochem Biophys 237:490-503 (1985)
DOI:10.1016/0003-9861(85)90302-9
  Sequence
[zma:732785]
Reference
3  [PMID:10683263]
  Authors
Chastain CJ, Botschner M, Harrington GE, Thompson BJ, Mills SE, Sarath G, Chollet R
  Title
Further analysis of maize C(4) pyruvate,orthophosphate dikinase phosphorylation by its bifunctional regulatory protein using selective substitutions of the regulatory Thr-456 and catalytic His-458 residues.
  Journal
Arch Biochem Biophys 375:165-70 (2000)
DOI:10.1006/abbi.1999.1651
  Sequence
[zma:732785]
Reference
4  [PMID:16696949]
  Authors
Burnell JN, Chastain CJ
  Title
Cloning and expression of maize-leaf pyruvate, Pi dikinase regulatory protein gene.
  Journal
Biochem Biophys Res Commun 345:675-80 (2006)
DOI:10.1016/j.bbrc.2006.04.150
  Sequence
[zma:732785]
Reference
5  [PMID:17996018]
  Authors
Chastain CJ, Xu W, Parsley K, Sarath G, Hibberd JM, Chollet R
  Title
The pyruvate, orthophosphate dikinase regulatory proteins of Arabidopsis possess  a novel, unprecedented Ser/Thr protein kinase primary structure.
  Journal
Plant J 53:854-63 (2008)
DOI:10.1111/j.1365-313X.2007.03366.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.7.11.32
IUBMB Enzyme Nomenclature: 2.7.11.32
ExPASy - ENZYME nomenclature database: 2.7.11.32
BRENDA, the Enzyme Database: 2.7.11.32

DBGET integrated database retrieval system