KEGG   ENZYME: 2.7.7.45Help
Entry
EC 2.7.7.45                 Enzyme                                 

Name
guanosine-triphosphate guanylyltransferase;
diguanosine tetraphosphate synthetase;
GTP-GTP guanylyltransferase;
Gp4G synthetase;
guanosine triphosphate-guanose triphosphate guanylyltransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
BRITE hierarchy
Sysname
GTP:GTP guanylyltransferase
Reaction(IUBMB)
2 GTP = diphosphate + P1,P4-bis(5'-guanosyl) tetraphosphate [RN:R00012]
Reaction(KEGG)
Substrate
GTP [CPD:C00044]
Product
diphosphate [CPD:C00013];
P1,P4-bis(5'-guanosyl) tetraphosphate [CPD:C01261]
Comment
Also acts, more slowly, on GDP to form P1,P3-bis(5'-guanosyl) triphosphate.
History
EC 2.7.7.45 created 1976
Reference
1  [PMID:4208243]
  Authors
Warner AH, Beers PC, Huang FL.
  Title
Biosynthesis of the diguanosine nucleotides. I. Purification and properties of an enzyme from yolk platelets of brine shrimp embryos.
  Journal
Can J Biochem 52:231-40 (1974)
Other DBs
ExplorEnz - The Enzyme Database: 2.7.7.45
IUBMB Enzyme Nomenclature: 2.7.7.45
ExPASy - ENZYME nomenclature database: 2.7.7.45
BRENDA, the Enzyme Database: 2.7.7.45
CAS: 54576-89-5

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