KEGG   ENZYME: 2.7.8.24Help
Entry
EC 2.7.8.24                 Enzyme                                 

Name
phosphatidylcholine synthase;
CDP-diglyceride-choline O-phosphatidyltransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
BRITE hierarchy
Sysname
CDP-diacylglycerol:choline O-phosphatidyltransferase
Reaction(IUBMB)
CDP-diacylglycerol + choline = CMP + phosphatidylcholine [RN:R05794]
Reaction(KEGG)
Substrate
CDP-diacylglycerol [CPD:C00269];
choline [CPD:C00114]
Product
CMP [CPD:C00055];
phosphatidylcholine [CPD:C00157]
Comment
Requires divalent cations, with Mn2+ being more effective than Mg2+.
History
EC 2.7.8.24 created 2001
Pathway
ec00564  Glycerophospholipid metabolism
ec01110  Biosynthesis of secondary metabolites
Orthology
K01004  phosphatidylcholine synthase
Genes
PAE: PA3857(pcs)
PAEV: N297_3983
PAEI: N296_3983
PAU: PA14_14110(pcs)
PAP: PSPA7_1254
PAG: PLES_11171(pcs)
PAF: PAM18_1081(pcs)
PNC: NCGM2_5046(pcs)
PAEB: NCGM1900_1117(pcs)
PDK: PADK2_05030
PAEP: PA1S_05535
PAEM: U769_05570
PAEL: T223_05485
PAEU: BN889_04288(pcs)
PAEG: AI22_28080
PAEC: M802_3981
PAEO: M801_3849
PMY: Pmen_3554
PMK: MDS_3820
PPSE: BN5_1012(pcs)
PCQ: PcP3B5_50360(pcs)
PSB: Psyr_0866
PSYR: N018_21340
PFL: PFL_4055(pcs)
PPRC: PFLCHA0_c41140(pcs)
PPRO: PPC_4154
PFO: Pfl01_2093(pcs)
PFS: PFLU_2780
PFC: PflA506_2915(pcs)
PFW: PF1751_v1c24430(pcs)
PFB: VO64_0110
PMAN: OU5_5911
PKC: PKB_0999
PSES: PSCI_0942
PSEM: TO66_11955
PSOS: POS17_4149
PANR: A7J50_2660
PSET: THL1_1610
PSIL: PMA3_17310
LPN: lpg1584
LPH: LPV_1721(lidK)
LPO: LPO_1604(lidK)
LPM: LP6_1562
LPF: lpl1441(lidK)
LPP: lpp1542(lidK)
LPC: LPC_1009(lidK)
LPA: lpa_02301(lidK)
LPE: lp12_1522
LLO: LLO_1806(lidK)
LFA: LFA_1639(pcsA)
LHA: LHA_1557
LCD: clem_07125(pcsA)
LLG: 44548918_01204(lidK)
TMC: LMI_1459
FTU: FTT_1563(pcs)
FTQ: RO31_1837
FTF: FTF1563(pcs)
FTW: FTW_0364
FTT: FTV_1491(pcs)
FTG: FTU_1576(pcs)
FTL: FTL_0545
FTH: FTH_0547(pcs)
FTA: FTA_0578
FTS: F92_02975
FTI: FTS_0547(pcs)
FTC: DA46_140
FTV: CH67_856
FTZ: CH68_589
FTM: FTM_0336(pcs)
FTN: FTN_1471(pcs)
FTX: AW25_530
FTD: AS84_1029
FTY: CH70_459
FPH: Fphi_1204
FPT: BZ13_801
FPI: BF30_1451
FPM: LA56_987
FPX: KU46_108
FPZ: LA55_1706
FPJ: LA02_822
FNA: OOM_0755
HAM: HALO0732
PLG: NCTC10937_03620(pcs)
DRT: Dret_1145
MLO: mll0506
MES: Meso_1695
AMIH: CO731_03463(pcs)
PLA: Plav_1484
RBS: RHODOSMS8_02799(pcs)
SME: SMc00247(pcs)
SMX: SM11_chr1736(pcs)
SMI: BN406_01424(pcs)
SMEL: SM2011_c00247(pcs)
SMER: DU99_09125
SMD: Smed_1420
RHI: NGR_c14490(pcs)
SFH: SFHH103_01344(pcs)
SFD: USDA257_c36660(pcs)
SIX: BSY16_1211(pcs)
SAME: SAMCFNEI73_Ch1722(pcs)
EAD: OV14_2758(pcs)
ATU: Atu1793(pcs)
ARA: Arad_2343(pcs)
ATF: Ach5_17200(pcs)
AVI: Avi_2165(pcs)
AGR: AGROH133_06819(pcs)
AGC: BSY240_566(pcs)
RET: RHE_CH02079(pcs)
REL: REMIM1_CH02087(pcs)
REP: IE4803_CH02091(pcs)
REI: IE4771_CH02179(pcs)
RLE: RL2370(pcs)
RLG: Rleg_1898
RIR: BN877_I1759(pcs)
RHL: LPU83_2441(pcs)
RGA: RGR602_CH01873(pcs)
RHN: AMJ98_CH02131(pcs)
RPHA: AMC79_CH02203(pcs)
RHT: NT26_1825(pcs)
RHX: AMK02_CH02141(pcs)
RHK: Kim5_CH02191(pcs)
LAA: WSI_03545
LSO: CKC_04930
LAR: lam_551(pssA)
SHZ: shn_09545
BME: BMEII0695
BMEL: DK63_2546(pcs)
BMEE: DK62_2861(pcs)
BMF: BAB2_0668
BMB: BruAb2_0652(pcs)
BABO: DK55_2636(pcs)
BABR: DO74_3054(pcs)
BABT: DK49_2601(pcs)
BABB: DK48_3161(pcs)
BABU: DK53_2641(pcs)
BABS: DK51_2123(pcs)
BABC: DO78_2416(pcs)
BMS: BRA0572(pcs)
BSI: BS1330_II0567(pcs)
BSF: BSS2_II0544(pcs)
BSZ: DK67_2566(pcs)
BSV: BSVBI22_B0566(pcs)
BOV: BOV_A0538
BOL: BCOUA_II0572(pcs)
BCAR: DK60_2283(pcs)
BCAS: DA85_13225
BMR: BMI_II566(pcs)
BPP: BPI_II624(pcs)
BPV: DK65_3058(pcs)
BVL: BF3285c2_0104(pcs)
OAN: Oant_3634
OAH: DR92_2849(pcs)
OCH: CES85_3969(pcs)
BJA: bll4585(pcs)
BRA: BRADO3781
BBT: BBta_4148
BRS: S23_35260(pcs)
AOL: S58_38290
BRAD: BF49_6912
RPA: RPA2672
RPB: RPB_2842
RPC: RPC_2618
RPD: RPD_2630
RPE: RPE_2798
RPT: Rpal_2947
NWI: Nwi_1506
NHA: Nham_2046
OCA: OCAR_6201
VGO: GJW-30_1_03178(pcs)
BHE: BH08530(pcsA)
BHN: PRJBM_00839(pcsA)
BHS: BM1374165_00938(pcsA)
BQU: BQ06040(pcsA)
BQR: RM11_0578
BBK: BARBAKC583_0817(pcs)
BTR: BT_1173
BTX: BM1374166_01107(pcsA)
BGR: Bgr_10750(pcsA)
BCD: BARCL_0765(pcsA)
BAUS: BAnh1_06510(pcs)
BVN: BVwin_07600(pcs)
BANC: PU02_0969
SNO: Snov_1703
RVA: Rvan_1366
BVR: BVIR_1798
MSC: BN69_0578
MMED: Mame_03140(pcs)
THD: BHV28_08120(pcs)
HDI: HDIA_2460(pcs)
SIL: SPO3131(pcs)
RSP: RSP_0565
RCP: RCAP_rcc03206(pcs)
JAN: Jann_1029
RDE: RD1_2077(pcs)
PDE: Pden_0811
PSF: PSE_3186(pcs)
PGA: PGA1_c05740(pcs)
PGL: PGA2_c05300(pcs)
PGD: Gal_02932
PHP: PhaeoP97_02782(pcs)
PPIC: PhaeoP14_00496(pcs)
OTM: OSB_06900(pcs)
PTP: RCA23_c09120(pcs)
MALG: MALG_02844
SPSE: SULPSESMR1_02217(pcs)
RMM: ROSMUCSMR3_00993(pcs)
AHT: ANTHELSMS3_01509(pcs)
RCE: RC1_1051(pcs)
AZL: AZL_005000(pcs)
COA: DR71_943
KFL: Kfla_2262
GOB: Gobs_4045
MMAR: MODMU_2418
AHE: Arch_0709
TPYO: X956_00955
RXY: Rxyl_0272
TRA: Trad_0527
RBA: RB4506
PLH: VT85_04340(pcs)
IPA: Isop_1798
SACI: Sinac_5705
PBOR: BSF38_02387(pcs)
BBU: BB_0249
BBUR: L144_01225
BGA: BG0251
BGB: KK9_0253
BGN: BgCN_0252
BAFT: P612_01245
BAFE: BAFK78_244
BCHI: OY14_01225
BTU: BT0249
BHR: BH0249
BDU: BDU_250
BRE: BRE_249
BCW: Q7M_252
BMIY: RJ61_01205
BPAK: X966_01245
BANE: N187_01185
ABAC: LuPra_05619(pcs)
SRU: SRU_0340
SRM: SRM_00419(pssA)
MOX: DAMO_0834
 » show all
Taxonomy
Reference
1  [PMID:10391951]
  Authors
de Rudder KE, Sohlenkamp C, Geiger O.
  Title
Plant-exuded choline is used for rhizobial membrane lipid biosynthesis by phosphatidylcholine synthase.
  Journal
J Biol Chem 274:20011-6 (1999)
DOI:10.1074/jbc.274.28.20011
  Sequence
[sme:SMc00247]
Reference
2  [PMID:10858449]
  Authors
Sohlenkamp C, de Rudder KE, Rohrs V, Lopez-Lara IM, Geiger O.
  Title
Cloning and characterization of the gene for phosphatidylcholine synthase.
  Journal
J Biol Chem 275:18919-25 (2000)
DOI:10.1074/jbc.M000844200
  Sequence
[sme:SMc00247]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.8.24
IUBMB Enzyme Nomenclature: 2.7.8.24
ExPASy - ENZYME nomenclature database: 2.7.8.24
BRENDA, the Enzyme Database: 2.7.8.24
CAS: 243666-86-6

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