KEGG   ENZYME: 2.8.2.16Help
Entry
EC 2.8.2.16                 Enzyme                                 

Name
thiol sulfotransferase;
phosphoadenylylsulfate-thiol sulfotransferase;
PAPS sulfotransferase;
adenosine 3'-phosphate 5'-sulphatophosphate sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate:thiol S-sulfotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate [RN:R01236]
Reaction(KEGG)
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
thiol [CPD:C00145]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
S-alkyl thiosulfate [CPD:C02885]
Comment
Also acts on dithiols; substrates include glutathione, dithioerythritol and 2,3-mercaptopropanol.
History
EC 2.8.2.16 created 1984
Reference
1  [PMID:24424637]
  Authors
Schmidt A
  Title
The adenosine-5'-phosphosulfate sulfotransferase from spinach (Spinacea oleracea  L.). Stabilization, partial purification, and properties.
  Journal
Planta 130:257-63 (1976)
DOI:10.1007/BF00387830
Reference
2
  Authors
Schmidt, A. and Christen, U.
  Title
A PAPS-dependent sulfotransferase in Cyanophora paradoxa inhibited by 5'-AMP, 5'-ADP and APS.
  Journal
Z Naturforsch C: Biosci 34:222-228 (1979)
Reference
3
  Authors
Tsang, M.
  Title
L.-S. and Schiff, J.A. Studies of sulfate utilization by algae. 17. Reactions of the adenosine 5'-phosphosulfate (APS) sulfotransferase from Chlorella and studies of model reactions which explain the diversity of side products with thiols.
  Journal
Plant Cell Physiol 17:1209-1220 (1976)
Other DBs
ExplorEnz - The Enzyme Database: 2.8.2.16
IUBMB Enzyme Nomenclature: 2.8.2.16
ExPASy - ENZYME nomenclature database: 2.8.2.16
BRENDA, the Enzyme Database: 2.8.2.16
CAS: 70356-45-5

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