KEGG   ENZYME: 2.8.2.18Help
Entry
EC 2.8.2.18                 Enzyme                                 

Name
cortisol sulfotransferase;
glucocorticosteroid sulfotransferase;
glucocorticoid sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate:cortisol 21-sulfotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + cortisol = adenosine 3',5'-bisphosphate + cortisol 21-sulfate [RN:R02839]
Reaction(KEGG)
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
cortisol [CPD:C00735]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
cortisol 21-sulfate [CPD:C02822]
History
EC 2.8.2.18 created 1986
Reference
1  [PMID:6957246]
  Authors
Singer SS, Brill B.
  Title
Enzymatic sulfation of steroids. XVII. The properties of the glucocorticoid sulfotransferase activity of guinea pig liver cytosol.
  Journal
Biochim Biophys Acta 712:590-6 (1982)
DOI:10.1016/0005-2760(82)90287-9
Reference
2  [PMID:1278101]
  Authors
Singer SS, Giera D, Johnson J, Sylvester S.
  Title
Enzymatic sulfation of steroids: I. The enzymatic basis for the sex difference in cortisol sulfation by rat liver preparations.
  Journal
Endocrinology 98:963-74 (1976)
DOI:10.1210/endo-98-4-963
Other DBs
ExplorEnz - The Enzyme Database: 2.8.2.18
IUBMB Enzyme Nomenclature: 2.8.2.18
ExPASy - ENZYME nomenclature database: 2.8.2.18
BRENDA, the Enzyme Database: 2.8.2.18
CAS: 59782-20-6

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