KEGG   ENZYME: 2.8.2.20Help
Entry
EC 2.8.2.20                 Enzyme                                 

Name
protein-tyrosine sulfotransferase;
tyrosylprotein sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate [RN:R02586]
Reaction(KEGG)
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
protein tyrosine [CPD:C00585]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
protein tyrosine-O-sulfate [CPD:C03721]
Comment
The tyrosine residues of some specific proteins of rat pheochromocytoma cells act as acceptors.
History
EC 2.8.2.20 created 1986
Orthology
K01021  protein-tyrosine sulfotransferase
K22218  protein-tyrosine sulfotransferase
Genes
HSA: 8459(TPST2) 8460(TPST1)
PTR: 458726(TPST2) 472398(TPST1)
PPS: 100981666(TPST2) 100995854(TPST1)
GGO: 101139944(TPST2) 101146881(TPST1)
PON: 100454434(TPST1) 100457197(TPST2)
NLE: 100602727(TPST1) 100606069(TPST2)
MCC: 696626(TPST1) 715338(TPST2)
MCF: 101865653(TPST2) 102139730(TPST1)
CSAB: 103223095(TPST2) 103246579(TPST1)
RRO: 104671939(TPST2) 104676249(TPST1)
RBB: 108515847(TPST2) 108543856(TPST1)
CJC: 100402781(TPST2) 100415662(TPST1)
SBQ: 101027659(TPST1) 101048210 101053684(TPST2)
MMU: 22021(Tpst1) 22022(Tpst2)
RNO: 288617(Tpst1) 288719(Tpst2)
CGE: 100757649(Tpst1) 100771893(Tpst2) 107977120
NGI: 103738944(Tpst1) 103746732(Tpst2)
HGL: 101711599(Tpst1) 101717396(Tpst2)
CCAN: 109688825(Tpst1) 109693032(Tpst2)
OCU: 100338693(TPST2) 100345464(TPST1)
TUP: 102478726(TPST2) 102479475(TPST1)
CFA: 486332(TPST2) 489788(TPST1)
AML: 100474327(TPST1) 100476408(TPST2)
UMR: 103659261(TPST2) 103670182(TPST1)
ORO: 101364016(TPST1) 101384192(TPST2)
FCA: 101091155(TPST2) 101101278(TPST1)
PTG: 102958179(TPST2) 102963176(TPST1)
AJU: 106972860(TPST1) 106978227(TPST2)
BTA: 513004(TPST1) 540183(TPST2)
BOM: 102276807(TPST1) 102284382(TPST2)
BIU: 109571371(TPST2) 109578736(TPST1)
PHD: 102325548(TPST2) 102337614(TPST1)
CHX: 102182899(TPST2) 102187284(TPST1)
OAS: 101104858(TPST2) 101110019(TPST1)
SSC: 100154448(TPST2) 100517581(TPST1)
CFR: 102503921(TPST2) 102509002(TPST1)
CDK: 105089699(TPST1) 105099484(TPST2)
BACU: 103003690(TPST2) 103015335(TPST1)
LVE: 103074713(TPST2) 103089525(TPST1)
OOR: 101269603(TPST2) 101272677(TPST1)
ECB: 100059398(TPST2) 100061873(TPST1)
EPZ: 103550028(TPST2) 103558028(TPST1)
EAI: 106831852(TPST1) 106841699(TPST2)
MYB: 102249043(TPST2) 102258440(TPST1) 102259926
MYD: 102762909(TPST2) 102771855(TPST1)
HAI: 109377435(TPST1) 109394122(TPST2)
RSS: 109438565(TPST1) 109460329(TPST2)
PALE: 102880813(TPST2) 102882492(TPST1)
LAV: 100665727(TPST2) 100670456(TPST1)
MDO: 100009937(TPST1) 100011282(TPST2)
SHR: 100915171(TPST1)
OAA: 100075156(TPST2) 100081244(TPST1)
GGA: 416910(TPST2) 417546(TPST1)
MGP: 100542914(TPST2) 104909262(TPST1)
CJO: 107321410(TPST2) 107322498(TPST1)
APLA: 101791156(TPST2) 101791667(TPST1)
ACYG: 106031072(TPST2) 106041454(TPST1)
TGU: 100224714(TPST2) 100227687 100231926(TPST1)
GFR: 102037542(TPST2) 102039260(TPST1)
FAB: 101808873(TPST1) 101812318(TPST2)
PHI: 102103318(TPST1) 102109477(TPST2)
PMAJ: 107211790(TPST2) 107212880(TPST1)
CCAE: 111936467(TPST2) 111946200(TPST1)
CCW: 104688646(TPST2) 104691080(TPST1)
FPG: 101912194(TPST2) 101919555(TPST1)
FCH: 102054159(TPST1) 102058320(TPST2)
CLV: 102086711(TPST1) 102091967(TPST2)
EGZ: 104122582(TPST2) 104131922(TPST1)
AAM: 106492551(TPST2) 106495363(TPST1)
ASN: 102381170(TPST1) 102385474(TPST2)
AMJ: 102560068(TPST2) 102566332(TPST1)
PSS: 102453626(TPST1) 102460081(TPST2)
CMY: 102932566(TPST1) 102946687(TPST2)
CPIC: 101949330(TPST2) 101952533(TPST1)
PVT: 110083448(TPST2) 110084505(TPST1)
PBI: 103047966(TPST2) 103063767(TPST1)
GJA: 107112497(TPST1) 107118892(TPST2)
XLA: 108707091(tpst2.S) 108709642 444016(tpst1.L) 495291(tpst2.L)
XTR: 549785(tpst2) 595028(tpst1)
NPR: 108787293(TPST1) 108793978(TPST2)
DRE: 30677(tpst1) 393171(tpst1l)
IPU: 100304582(tpst2) 108277496 108279036(tpst1)
TRU: 101064708(tpst1) 101073940
LCO: 104928580(tpst1)
NCC: 104950625(tpst1) 104964488
MZE: 101477589 101482118(tpst1)
XMA: 102219783(tpst1) 102228781
PRET: 103474349(tpst1) 103475655
NFU: 107380745(tpst1) 107386765
KMR: 108238895(tpst1) 108248066
CSEM: 103377640 103395453(tpst1)
SDU: 111217243(tpst1) 111226285
HCQ: 109532038(tpst1)
BPEC: 110155918(tpst1) 110168239
MALB: 109957371(tpst1) 109960022
SFM: 108930048 108932415(tpst1)
LCM: 102364059(TPST2) 102364758(TPST1)
CMK: 103180643(tpst1) 103189950(tpst2)
CIN: 100181744
SPU: 579762
DME: Dmel_CG32632(Tango13)
DSI: Dsimw501_GD17135(Dsim_GD17135)
MDE: 101893374
AAG: 5572543
AME: 552278
BIM: 100745484
BTER: 100648160
SOC: 105207782
AEC: 105145889
PBAR: 105432715
HST: 105189261
DQU: 106752046
CFO: 105248709
LHU: 105673267
PGC: 109857848
PCF: 106785477
NVI: 100123184
MDL: 103568660
TCA: 656373
DPA: 109545455
NVL: 108569329
BMOR: 101739802
PMAC: 106713855
PRAP: 110995677
HAW: 110379498
PXY: 105394176
API: 100160328
DNX: 107167197
CLEC: 106664801
FCD: 110851292
TUT: 107367096
CEL: CELE_F42G9.8(tpst-2) CELE_Y111B2A.15(tpst-1)
BMY: Bm1_44780
TSP: Tsp_01013
OBI: 106875251
EGL: EGR_02151
EPA: 110254891
ADF: 107334545
AQU: 100631816
ATH: AT1G08030(TPST)
CRB: 17898466
CPAP: 110826114
CIT: 102622908
TCC: 18590889
GRA: 105788953
DZI: 111285672
EGR: 104432883
GMX: 100810026
VRA: 106754522
VAR: 108338836
CCAJ: 109799316
CAM: 101493115
LJA: Lj0g3v0141259.1(Lj0g3v0141259.1) Lj0g3v0141259.2(Lj0g3v0141259.2) Lj0g3v0141259.3(Lj0g3v0141259.3)
FVE: 101295888
PPER: 18772752
PMUM: 103343350
PAVI: 110772506
ZJU: 107411365
CSV: 101207379
CMO: 103500982
MCHA: 111020531
RCU: 8266268
JCU: 105628080
HBR: 110645003
POP: 7463302
VVI: 100255229
SLY: 101261094
SPEN: 107005098
SOT: 102585997
CANN: 107848027
NSY: 104242491
NTO: 104113366
BVG: 104903227
SOE: 110776614
NNU: 104594871
OSA: 9267276
DOSA: Os06t0158200-01(Os06g0158200)
OBR: 102703043
BDI: 100828854
ATS: 109765635(LOC109765635)
SITA: 101764318
PDA: 103718253
EGU: 105055663
PEQ: 110024958
AOF: 109823173
ATR: 18995795
PPP: 112293313
CRE: CHLREDRAFT_189798(CGL13)
APRO: F751_2022
 » show all
Taxonomy
Reference
1  [PMID:6577005]
  Authors
Lee RW, Huttner WB.
  Title
Tyrosine-O-sulfated proteins of PC12 pheochromocytoma cells and their sulfation by a tyrosylprotein sulfotransferase.
  Journal
J Biol Chem 258:11326-34 (1983)
Other DBs
ExplorEnz - The Enzyme Database: 2.8.2.20
IUBMB Enzyme Nomenclature: 2.8.2.20
ExPASy - ENZYME nomenclature database: 2.8.2.20
BRENDA, the Enzyme Database: 2.8.2.20
CAS: 87588-33-8

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