KEGG   ENZYME: 2.8.3.13Help
Entry
EC 2.8.3.13                 Enzyme                                 

Name
succinate---hydroxymethylglutarate CoA-transferase;
hydroxymethylglutarate coenzyme A-transferase;
dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase
Class
Transferases;
Transferring sulfur-containing groups;
CoA-transferases
BRITE hierarchy
Sysname
succinyl-CoA:3-hydroxy-3-methylglutarate CoA-transferase
Reaction(IUBMB)
succinyl-CoA + 3-hydroxy-3-methylglutarate = succinate + (S)-3-hydroxy-3-methylglutaryl-CoA [RN:R02084]
Reaction(KEGG)
Substrate
succinyl-CoA [CPD:C00091];
3-hydroxy-3-methylglutarate [CPD:C03761]
Product
succinate [CPD:C00042];
(S)-3-hydroxy-3-methylglutaryl-CoA [CPD:C00356]
Comment
Malonyl-CoA can also act as donor, but more slowly.
History
EC 2.8.3.13 created 1984
Orthology
K18703  succinate---hydroxymethylglutarate CoA-transferase
Genes
HSA: 79783(SUGCT)
PTR: 463372(SUGCT)
PPS: 100986046(SUGCT)
GGO: 101151689(SUGCT)
PON: 100439966(SUGCT)
NLE: 100604796(SUGCT)
MCC: 702855(SUGCT)
MCF: 102117690(SUGCT)
CSAB: 103226178(SUGCT)
RRO: 104663124(SUGCT)
RBB: 108526580(SUGCT)
CJC: 100399458(SUGCT)
SBQ: 101045888(SUGCT)
MMU: 192136(Sugct)
MCAL: 110308310(Sugct)
MPAH: 110333816(Sugct)
RNO: 361253(Sugct)
MUN: 110545457(Sugct)
CGE: 100770206(Sugct)
NGI: 103736749(Sugct)
HGL: 101704628(Sugct)
CCAN: 109699563(Sugct)
OCU: 100344733(SUGCT)
TUP: 102500635(SUGCT)
CFA: 483247(SUGCT)
VVP: 112925810(SUGCT)
AML: 100466463(SUGCT)
UMR: 103674695(SUGCT)
UAH: 113258116(SUGCT)
ORO: 101370482(SUGCT) 101380249
ELK: 111157075
FCA: 101090248(SUGCT)
PTG: 102969712(SUGCT)
PPAD: 109268012(SUGCT)
AJU: 106974432(SUGCT)
BTA: 100125578(SUGCT)
BOM: 102277643(SUGCT)
BIU: 109557920(SUGCT)
BBUB: 102403448(SUGCT)
CHX: 102189185(SUGCT)
OAS: 101121005(SUGCT)
SSC: 102168155(SUGCT)
CFR: 102518036(SUGCT)
CDK: 105088268(SUGCT)
BACU: 103011770(SUGCT)
LVE: 103073879(SUGCT)
OOR: 101274229(SUGCT)
DLE: 111184492(SUGCT)
PCAD: 102978044(SUGCT)
ECB: 100063665(SUGCT)
EPZ: 103548468(SUGCT)
EAI: 106841054(SUGCT)
MYB: 102255717(SUGCT)
MYD: 102755997(SUGCT)
MNA: 107532777(SUGCT)
HAI: 109388809(SUGCT)
DRO: 112302737(SUGCT)
RAY: 107512712(SUGCT)
MJV: 108391317 108407960(SUGCT)
LAV: 100662735(SUGCT)
TMU: 101358340
MDO: 100017716(SUGCT)
SHR: 100917495 100923323(SUGCT)
PCW: 110192937(SUGCT)
OAA: 100076800(SUGCT)
GGA: 420768(SUGCT)
MGP: 100541558(SUGCT)
CJO: 107309842(SUGCT)
NMEL: 110393207(SUGCT)
APLA: 101795646(SUGCT)
ACYG: 106042881(SUGCT)
TGU: 100220077(SUGCT)
LSR: 110471392(SUGCT)
SCAN: 103819414(SUGCT)
GFR: 102042813(SUGCT)
FAB: 101815381(SUGCT)
PHI: 102102839(SUGCT)
PMAJ: 107199809(SUGCT)
CCAE: 111923670(SUGCT)
CCW: 104688907(SUGCT)
ETL: 114068676(SUGCT) 114070793
FPG: 101914214(SUGCT)
FCH: 102058344(SUGCT)
CLV: 102092162(SUGCT)
EGZ: 104124844(SUGCT)
NNI: 104012418(SUGCT)
ACUN: 113477581(SUGCT)
PADL: 103914775(SUGCT)
AAM: 106495271(SUGCT)
ASN: 102380883(SUGCT)
AMJ: 102565653(SUGCT)
PSS: 102457624(SUGCT)
CMY: 102938246(SUGCT)
CPIC: 101932936(SUGCT)
ACS: 100560657(sugct)
PVT: 110076201(SUGCT) 110086670
PBI: 103051719(SUGCT) 112541744
PMUR: 107284934(SUGCT)
TSR: 106552975(SUGCT)
PMUA: 114607372(SUGCT)
GJA: 107125736(SUGCT)
XLA: 734617(sugct.L)
XTR: 100490876(sugct)
NPR: 108789606(SUGCT)
DRE: 619244(sugct)
SGH: 107588103
IPU: 108272202(sugct)
PHYP: 113545418(sugct)
AMEX: 103046221(sugct)
EEE: 113579379(sugct)
TRU: 101079570(sugct)
LCO: 104934798(sugct)
NCC: 104958094
ONL: 100690336(sugct)
OLA: 101160363(sugct)
XMA: 102217127(sugct)
XCO: 114136606(sugct)
PRET: 103460142(sugct)
CVG: 107103354(sugct)
NFU: 107396590(sugct)
ALIM: 106527658(sugct)
CSEM: 103377338(sugct)
POV: 109643934(sugct) 109645926
LCF: 108894671(sugct)
SDU: 111237409(sugct)
HCQ: 109530300(sugct)
BPEC: 110162694(sugct)
MALB: 109974978(sugct)
OTW: 112228026(sugct)
SALP: 111953576(sugct)
ELS: 105019401(sugct)
SFM: 108942414(sugct)
PKI: 111837840(sugct)
CMK: 103181542(sugct)
CIN: 100182301
SPU: 585781
APLC: 110973554
SKO: 100367923
DME: Dmel_CG10877(CG10877)
DER: 6553691
DSI: Dsimw501_GD20057(Dsim_GD20057)
DSR: 110188221
DPE: 6595072
DMN: 108155165
DWI: 6649635
DAZ: 108615476
DNV: 108653570
MDE: 101898519
LCQ: 111679068
AAG: 5579340
AALB: 109622879
AME: 102653793
BIM: 100749167
BTER: 100642253
CCAL: 108628205
OBB: 114878337
SOC: 105203633
MPHA: 105835014
AEC: 105143279
ACEP: 105623357
PBAR: 105424931
VEM: 105569340
HST: 105184591
DQU: 106744777
CFO: 105256083
LHU: 105678836
PGC: 109856317
OBO: 105278275
PCF: 106793590
NVI: 100115846
MDL: 103577513
TCA: 660876
DPA: 109537429
ATD: 109600725
NVL: 108565438
BMOR: 692874
BMAN: 114239438
PMAC: 106712775
PRAP: 110991305
HAW: 110380602
TNL: 113501138
PXY: 105381801
API: 100168975
DNX: 107162995
AGS: 114124321
RMD: 113556875
BTAB: 109030047
CLEC: 106670613
FCD: 110846887
PVM: 113814628
TUT: 107361994
PCAN: 112565218
CRG: 105328315
MYI: 110464562
OBI: 106869531
EPA: 110254819
ADF: 107331705
AMIL: 114965027
PDAM: 113670225
SPIS: 111327396
HMG: 100199476
NCR: NCU07298
NTE: NEUTE1DRAFT61271(NEUTE1DRAFT_61271)
MGR: MGG_13032
MAW: MAC_03060
CMT: CCM_03858
MBE: MBM_09509
ANI: AN4230.2
ANG: ANI_1_676164(An18g05120)
ABE: ARB_05424
TVE: TRV_03845
PNO: SNOG_02523(SNOG_02522) SNOG_04148
CNE: CNB03190
CNB: CNBB2500
ABP: AGABI1DRAFT113921(AGABI1DRAFT_113921)
ABV: AGABI2DRAFT193757(AGABI2DRAFT_193757)
 » show all
Taxonomy
Reference
1  [PMID:6946836]
  Authors
Deana R, Rigoni F, Deana AD, Galzigna L.
  Title
Submitochondrial localization and partial purification of the succinylCoA: 3-hydroxy-3-methylglutarate coenzyme A transferase from rat liver.
  Journal
Biochim Biophys Acta 662:119-24 (1981)
DOI:10.1016/0005-2744(81)90231-X
Other DBs
ExplorEnz - The Enzyme Database: 2.8.3.13
IUBMB Enzyme Nomenclature: 2.8.3.13
ExPASy - ENZYME nomenclature database: 2.8.3.13
BRENDA, the Enzyme Database: 2.8.3.13
CAS: 80237-90-7

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