KEGG   ENZYME: 3.1.1.41Help
Entry
EC 3.1.1.41                 Enzyme                                 

Name
cephalosporin-C deacetylase;
cephalosporin C acetyl-hydrolase;
cephalosporin C acetylase;
cephalosporin acetylesterase;
cephalosporin C acetylesterase;
cephalosporin C acetyl-esterase;
cephalosporin C deacetylase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
cephalosporin-C acetylhydrolase
Reaction(IUBMB)
cephalosporin C + H2O = deacetylcephalosporin C + acetate [RN:R03062]
Reaction(KEGG)
Substrate
cephalosporin C [CPD:C00916];
H2O [CPD:C00001]
Product
deacetylcephalosporin C [CPD:C03112];
acetate [CPD:C00033]
Comment
Hydrolyses the acetyl ester bond on the 10-position of the antibiotic cephalosporin C.
History
EC 3.1.1.41 created 1976
Pathway
ec00311  Penicillin and cephalosporin biosynthesis
ec01130  Biosynthesis of antibiotics
Orthology
K01060  cephalosporin-C deacetylase
Genes
CATE: C2869_07180
MMT: Metme_1885
MDN: JT25_021245
MDH: AYM39_10145
MKO: MKLM6_2137
MPSY: CEK71_05805
TVI: Thivi_2764
TEE: Tel_08835
TSY: THSYN_30695
MME: Marme_3943
MLO: mlr6993
ARA: Arad_9051
RLE: RL2908
RLG: Rleg_2440
MGM: Mmc1_2518
BSU: BSU03180(cah)
BSR: I33_0363
BSL: A7A1_1880
BSH: BSU6051_03180(cah)
BSUT: BSUB_00367(cah)
BSUL: BSUA_00367(cah)
BSUS: Q433_01915
BSS: BSUW23_01625(cah)
BST: GYO_0523
BSO: BSNT_06647(cah)
BSQ: B657_03180(cah)
BSX: C663_0308(cah)
BLI: BL01713(cah)
BLD: BLi00379(cah)
BLH: BaLi_c03950(cah)
BAY: RBAM_003420(cah)
BAQ: BACAU_0285(cah)
BYA: BANAU_0284(cah)
BAMP: B938_01465
BAML: BAM5036_0301(cah)
BAMA: RBAU_0315(cah)
BAMN: BASU_0300(cah)
BAMB: BAPNAU_0285(cah)
BAMT: AJ82_01875
BAMY: V529_03050(cah)
BMP: NG74_00324(cah)
BAO: BAMF_0291(cah)
BAZ: BAMTA208_01460(cah)
BQL: LL3_00299(cah)
BXH: BAXH7_00302(cah)
BQY: MUS_0300(cah)
BAMI: KSO_017950
BAMC: U471_03020
BAMF: U722_01760
BHA: BH3326
BCL: ABC1769(cah)
BPU: BPUM_0297
BPUM: BW16_01880
BPUS: UP12_01885
BJS: MY9_0327
BACW: QR42_01840
BACP: SB24_08095
BACB: OY17_04375
BACY: QF06_00545
BACL: BS34A_03730(cah)
BALM: BsLM_0331
BGY: BGLY_0386(cah)
BBEV: BBEV_0471(cah)
AXL: AXY_21800(axe) AXY_22340(axe)
BSE: Bsel_0980
PPM: PPSC2_18660(cah3) PPSC2_24180(cah5)
PPO: PPM_3754(cah3) PPM_4801(cah5)
PSWU: SY83_03310
LLK: LLKF_1447(axe)
LLX: NCDO2118_1409(axe)
LLR: llh_7440
LLI: uc509_1372(axe)
LLW: kw2_1343
LLJ: LG36_1029(axe)
SPN: SP_1695
SPD: SPD_1506
SPR: spr1538(axe1)
SPW: SPCG_1668(axe1)
SJJ: SPJ_1589
SPX: SPG_1602(axe1)
SPV: SPH_1800
SPP: SPP_1712
SNP: SPAP_1703
SAG: SAG0041
SAN: gbs0040
SAK: SAK_0074
SGC: A964_0040
SAGM: BSA_740
SAGR: SAIL_770
SAGE: EN72_00375
SAGG: EN73_00375
SAGN: W903_0076(axe1)
SSA: SSA_0070(axe1)
SEZ: Sez_0253
SEQ: SZO_17040
SEQU: Q426_07955
SUB: SUB1651
SGT: SGGB_0215(axe1)
SMB: smi_0600
SOR: SOR_0547
STB: SGPB_0158(axe1)
SCF: Spaf_1050
SMN: SMA_192(cah)
STRN: SNAG_0541(axeA)
EFA: EF1236
EFL: EF62_1680
EFS: EFS1_1059
EFQ: DR75_300
ENE: ENT_06680
CPE: CPE1596
CPF: CPF_1848(axe1)
CBV: U729_2266(axe1)
CTH: Cthe_3063
HSC: HVS_10845(cah)
CCE: Ccel_0210
CSS: Cst_c14440(cah)
CSD: Clst_1394
CCEL: CCDG5_2025
DSY: DSY0351
DHD: Dhaf_0284
SGY: Sgly_0270
TIT: Thit_0191
CSC: Csac_2436
ATE: Athe_0152
TTM: Tthe_0984
SCO: SCO7057(SC4G1.23c)
SALB: XNR_3892
SMA: SAVERM_1302(axe1) SAVERM_1457(axe2)
SGB: WQO_23395
SHY: SHJG_2291
SVE: SVEN_6682
SALS: SLNWT_7151
SFI: SFUL_4907
SALU: DC74_6913
SALL: SAZ_35900
SLV: SLIV_03965(axeA)
SGU: SGLAU_03235(axeA)
STRE: GZL_01842
SLD: T261_1053
SAMB: SAM23877_1034(axeA)
SRW: TUE45_01052(axeA)
SLE: sle_63340(sle_63340)
SRN: A4G23_05285(axeA)
SNR: SNOUR_08235(axeA)
SMAL: SMALA_1210
KSK: KSE_04670(axe1) KSE_10120(axe2)
CMS: CMS0795
CMC: CMN_00165
ART: Arth_3303
ARR: ARUE_c34390(cah)
ARM: ART_3104
AAU: AAur_3303
ACH: Achl_3101
JDE: Jden_1761
XCE: Xcel_2723
IDO: I598_3177(axeA)
CFL: Cfla_0926
PACC: PAC1_01355
PACH: PAGK_0284
CACN: RN83_01750
ACIJ: JS278_00650(axeA)
KFL: Kfla_0274
SRO: Sros_2720
AMI: Amir_1984
SESP: BN6_23910
AHG: AHOG_17940(axeA)
SAQ: Sare_3004
ASE: ACPL_5484(axe1)
ACTN: L083_3285(axe1)
ACTS: ACWT_5353
SNA: Snas_3115
TBI: Tbis_1965
APV: Apar_0931
OLS: Olsu_1284
RCA: Rcas_1231
HAU: Haur_0886
ATM: ANT_24920
PBF: CFX0092_B0571(axeA)
TTR: Tter_0201
PBAS: SMSP2_02919(axeA)
LIE: LIF_A1498
LIS: LIL_12147
LBF: LBF_1671
LST: LSS_18918
BRM: Bmur_1237
BPW: WESB_0039
BIP: Bint_2614
BXY: BXY_25990
FLN: FLA_1626
MUC: MuYL_4073
TMW: THMA_0073
TMQ: THMB_0073
TMX: THMC_0073
TPT: Tpet_0847
TRQ: TRQ2_0870
TNA: CTN_0615
TNP: Tnap_0707
TLE: Tlet_0356
DTU: Dtur_0265
 » show all
Taxonomy
Reference
1  [PMID:4519146]
  Authors
Fujisawa Y, Shirafugi H, Kida M, Nara K, Yoneda M, Kanzaki T.
  Title
New findings on cephalosporin C biosynthesis.
  Journal
Nat New Biol 246:154-5 (1973)
Other DBs
ExplorEnz - The Enzyme Database: 3.1.1.41
IUBMB Enzyme Nomenclature: 3.1.1.41
ExPASy - ENZYME nomenclature database: 3.1.1.41
BRENDA, the Enzyme Database: 3.1.1.41
CAS: 52227-71-1

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