KEGG   ENZYME: 3.1.1.52Help
Entry
EC 3.1.1.52                 Enzyme                                 

Name
phosphatidylinositol deacylase;
phosphatidylinositol phospholipase A2;
phospholipase A2
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
1-phosphatidyl-D-myo-inositol 2-acylhydrolase
Reaction(IUBMB)
1-phosphatidyl-D-myo-inositol + H2O = 1-acylglycerophosphoinositol + a carboxylate [RN:R03360]
Reaction(KEGG)
Substrate
1-phosphatidyl-D-myo-inositol [CPD:C01194];
H2O [CPD:C00001]
Product
1-acylglycerophosphoinositol [CPD:C03819];
carboxylate [CPD:C00060]
History
EC 3.1.1.52 created 1984
Pathway
ec00564  Glycerophospholipid metabolism
Reference
1  [PMID:7083039]
  Authors
Gray NC, Strickland KP.
  Title
The purification and characterization of a phospholipase A2 activity from the 106,000 X g pellet (microsomal fraction) of bovine brain acting on phosphatidylinositol.
  Journal
Can J Biochem 60:108-17 (1982)
Reference
2  [PMID:7087686]
  Authors
Gray NC, Strickland KP.
  Title
On the specificity of a phospholipase A2 purified from the 106,000 X g pellet of bovine brain.
  Journal
Lipids 17:91-6 (1982)
DOI:10.1007/BF02535181
Other DBs
ExplorEnz - The Enzyme Database: 3.1.1.52
IUBMB Enzyme Nomenclature: 3.1.1.52
ExPASy - ENZYME nomenclature database: 3.1.1.52
BRENDA, the Enzyme Database: 3.1.1.52
CAS: 81604-94-6

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