KEGG   ENZYME: 3.1.1.63Help
Entry
EC 3.1.1.63                 Enzyme                                 

Name
11-cis-retinyl-palmitate hydrolase;
11-cis-retinol palmitate esterase;
RPH
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
11-cis-retinyl-palmitate acylhydrolase
Reaction(IUBMB)
11-cis-retinyl palmitate + H2O = 11-cis-retinol + palmitate [RN:R03049]
Reaction(KEGG)
Substrate
11-cis-retinyl palmitate [CPD:C03455];
H2O [CPD:C00001]
Product
11-cis-retinol [CPD:C00899];
palmitate [CPD:C00249]
Comment
Activated by bile salts.
History
EC 3.1.1.63 created 1989
Pathway
ec00830  Retinol metabolism
Reference
1  [PMID:3793734]
  Authors
Blaner WS, Das SR, Gouras P, Flood MT.
  Title
Hydrolysis of 11-cis- and all-trans-retinyl palmitate by homogenates of human retinal epithelial cells.
  Journal
J Biol Chem 262:53-8 (1987)
Reference
2  [PMID:6743673]
  Authors
Blaner WS, Prystowsky JH, Smith JE, Goodman DS.
  Title
Rat liver retinyl palmitate hydrolase activity. Relationship to cholesteryl oleate and triolein hydrolase activities.
  Journal
Biochim Biophys Acta 794:419-27 (1984)
DOI:10.1016/0005-2760(84)90008-0
Other DBs
ExplorEnz - The Enzyme Database: 3.1.1.63
IUBMB Enzyme Nomenclature: 3.1.1.63
ExPASy - ENZYME nomenclature database: 3.1.1.63
BRENDA, the Enzyme Database: 3.1.1.63
CAS: 106389-23-5

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