KEGG   ENZYME: 3.1.2.1Help
Entry
EC 3.1.2.1                  Enzyme                                 

Name
acetyl-CoA hydrolase;
acetyl-CoA deacylase;
acetyl-CoA acylase;
acetyl coenzyme A hydrolase;
acetyl coenzyme A deacylase;
acetyl coenzyme A acylase;
acetyl-CoA thiol esterase
Class
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
BRITE hierarchy
Sysname
acetyl-CoA hydrolase
Reaction(IUBMB)
acetyl-CoA + H2O = CoA + acetate [RN:R00227]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
H2O [CPD:C00001]
Product
CoA [CPD:C00010];
acetate [CPD:C00033]
History
EC 3.1.2.1 created 1961
Pathway
ec00620  Pyruvate metabolism
ec01100  Metabolic pathways
Orthology
K01067  acetyl-CoA hydrolase
Genes
HSA: 134526(ACOT12)
PTR: 461769(ACOT12)
PPS: 100970341(ACOT12)
GGO: 101152146(ACOT12)
PON: 100438971(ACOT12)
NLE: 100598208(ACOT12)
MCC: 711665(ACOT12)
MCF: 102142119(ACOT12)
CSAB: 103223934(ACOT12)
RRO: 104680192(ACOT12)
RBB: 108528919(ACOT12)
CJC: 100391176(ACOT12)
SBQ: 101041377(ACOT12)
MMU: 74156(Acot12)
MCAL: 110307632(Acot12)
MPAH: 110328781(Acot12)
RNO: 170570(Acot12)
MUN: 110566047(Acot12)
CGE: 100752768(Acot12)
NGI: 103750264(Acot12)
HGL: 101703913(Acot12)
CCAN: 109682295(Acot12)
OCU: 100338318(ACOT12)
TUP: 102476138(ACOT12)
CFA: 488925(ACOT12)
VVP: 112915585(ACOT12)
AML: 100476121(ACOT12)
UMR: 103681503(ACOT12)
UAH: 113254979(ACOT12)
ORO: 101382166(ACOT12)
FCA: 101091423(ACOT12)
PTG: 102960516(ACOT12)
PPAD: 109274913(ACOT12)
AJU: 106967948(ACOT12)
BTA: 525155(ACOT12)
BOM: 102273943(ACOT12)
BIU: 109562293(ACOT12)
BBUB: 102390801(ACOT12)
CHX: 102172148(ACOT12)
OAS: 101118188(ACOT12)
SSC: 100738062(ACOT12)
CFR: 102509429(ACOT12)
CDK: 105084844(ACOT12)
BACU: 102999602(ACOT12)
LVE: 103069255(ACOT12)
OOR: 101285482(ACOT12)
DLE: 111184738(ACOT12)
PCAD: 102986121(ACOT12)
ECB: 100073251(ACOT12)
EPZ: 103549612(ACOT12)
EAI: 106841156(ACOT12)
MYB: 102255432(ACOT12)
MYD: 102756728(ACOT12)
MNA: 107535082(ACOT12)
HAI: 109388132(ACOT12)
DRO: 112307478(ACOT12)
PALE: 102888499(ACOT12)
MJV: 108407043(ACOT12)
TMU: 101357788
MDO: 100015770(ACOT12)
SHR: 100919572(ACOT12)
PCW: 110222640(ACOT12)
OAA: 100081254(ACOT12)
GGA: 431627(ACOT12)
MGP: 104915280(ACOT12)
CJO: 107306526(ACOT12)
NMEL: 110389622(ACOT12)
APLA: 101791825(ACOT12)
ACYG: 106042718(ACOT12)
TGU: 100219385(ACOT12)
LSR: 110482520(ACOT12)
SCAN: 103823057(ACOT12)
GFR: 102035411(ACOT12)
FAB: 101810335(ACOT12)
PHI: 102112382(ACOT12)
PMAJ: 107216375(ACOT12)
CCAE: 111941640(ACOT12)
CCW: 104695825(ACOT12)
ETL: 114056129(ACOT12)
FPG: 101924947(ACOT12)
FCH: 102059422(ACOT12)
CLV: 102092439(ACOT12)
EGZ: 104128353(ACOT12)
NNI: 104022999(ACOT12)
ACUN: 113490327(ACOT12)
PADL: 103923438(ACOT12)
ASN: 102379080(ACOT12)
AMJ: 102570778(ACOT12)
PSS: 102459479(ACOT12)
CMY: 102944174(ACOT12)
CPIC: 101931735(ACOT12)
ACS: 100554997(acot12)
PVT: 110077334(ACOT12)
PBI: 103061492(ACOT12)
PMUR: 107286315(ACOT12)
PMUA: 114606537(ACOT12)
GJA: 107120563(ACOT12)
XLA: 444535(acot12.L)
XTR: 100170471(acot12)
NPR: 108787611(ACOT12)
DRE: 100536873(acot12)
SRX: 107758641(acot12)
SANH: 107658612(acot12)
SGH: 107588978
CCAR: 109071741(acot12)
SASA: 106568307
OTW: 112220242(acot12)
SALP: 111961784(acot12)
PKI: 111859863(acot12)
LCM: 102361204(ACOT12)
PXY: 105396710
SCE: YBL015W(ACH1)
ERC: Ecym_6197
KMX: KLMA_20042(ACH1)
NCS: NCAS_0B05550(NCAS0B05550)
NDI: NDAI_0B02890(NDAI0B02890)
TPF: TPHA_0C02890(TPHA0C02890)
TBL: TBLA_0E03560(TBLA0E03560)
TDL: TDEL_0B04500(TDEL0B04500)
KAF: KAFR_0C02850(KAFR0C02850)
PIC: PICST_78208(ACH1)
CAL: CAALFM_C502000CA(ACH1)
SLB: AWJ20_2963(ACH1)
NCR: NCU09770(acu-8)
NTE: NEUTE1DRAFT64379(NEUTE1DRAFT_64379)
MGR: MGG_06609
BFU: BCIN_04g01780(Bcach1)
MBE: MBM_05077
ANI: AN1547.2
ANG: ANI_1_938144(An16g07110)
PTE: PTT_11541
DFA: DFA_08685
REH: H16_B1368(h16_B1368)
AJS: Ajs_0123
GEO: Geob_0742(ato-1) Geob_2594(ato-2)
PPD: Ppro_0286
DAT: HRM2_15970(ach1)
MXA: MXAN_2285
SFU: Sfum_0389
BBA: Bd1620
RLE: pRL90030
BID: Bind_0767
LBF: LBF_0820
DFE: Dfer_2213
LBY: Lbys_1257
CCH: Cag_0060
MSE: Msed_1217
 » show all
Taxonomy
Reference
1  [PMID:12999747]
  Authors
GERGELY J, HELE P, RAMAKRISHNAN CV.
  Title
Succinyl and acetyl coenzyme a deacylases.
  Journal
J Biol Chem 198:324-34 (1952)
Other DBs
ExplorEnz - The Enzyme Database: 3.1.2.1
IUBMB Enzyme Nomenclature: 3.1.2.1
ExPASy - ENZYME nomenclature database: 3.1.2.1
BRENDA, the Enzyme Database: 3.1.2.1
CAS: 9027-54-7

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