KEGG   ENZYME: 3.1.2.21Help
Entry
EC 3.1.2.21                 Enzyme                                 

Name
dodecanoyl-[acyl-carrier-protein] hydrolase;
lauryl-acyl-carrier-protein hydrolase;
dodecanoyl-acyl-carrier-protein hydrolase;
dodecyl-acyl-carrier protein hydrolase;
dodecanoyl-[acyl-carrier protein] hydrolase;
dodecanoyl-[acyl-carrier-protein] hydrolase
Class
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
BRITE hierarchy
Sysname
dodecanoyl-[acyl-carrier protein] hydrolase
Reaction(IUBMB)
a dodecanoyl-[acyl-carrier protein] + H2O = an [acyl-carrier protein] + dodecanoate [RN:R04014]
Reaction(KEGG)
R04014;
(other) R08157 R08158
Show
Substrate
dodecanoyl-[acyl-carrier protein] [CPD:C05223];
H2O [CPD:C00001]
Product
[acyl-carrier protein] [CPD:C00229];
dodecanoate [CPD:C02679]
Comment
Acts on the acyl-carrier-protein thioester of C12 and, with a much lower activity, C14 fatty acids. The derivative of oleic acid is hydrolysed very slowly (cf. EC 3.1.2.14, oleoyl-[acyl-carrier-protein] hydrolase).
History
EC 3.1.2.21 created 1999
Pathway
ec00061  Fatty acid biosynthesis
ec01100  Metabolic pathways
Orthology
K01071  medium-chain acyl-[acyl-carrier-protein] hydrolase
K10781  fatty acyl-ACP thioesterase B
Genes
HSA: 55301(OLAH)
PTR: 450320(OLAH)
PPS: 100969629(OLAH)
PON: 100441345(OLAH)
NLE: 100601676(OLAH)
MCC: 697753(OLAH)
MCF: 102142933(OLAH)
CSAB: 103237931(OLAH)
RRO: 104664475(OLAH)
RBB: 108530852(OLAH)
CJC: 100402846(OLAH)
SBQ: 101043966(OLAH)
MMU: 99035(Olah)
RNO: 64669(Olah)
CGE: 100755723(Olah)
NGI: 103735189(Olah)
HGL: 101699165(Olah)
OCU: 100349940
TUP: 102488474(OLAH)
BTA: 617347(OLAH)
BOM: 102273387(OLAH)
BIU: 109567605(OLAH)
PHD: 102324441(OLAH)
CHX: 102180055(OLAH)
OAS: 101116669(OLAH)
SSC: 100627446(OLAH)
CFR: 102522778(OLAH)
CDK: 105104528(OLAH)
BACU: 103001653(OLAH)
ECB: 100068833(OLAH)
EPZ: 103556832(OLAH)
EAI: 106840468(OLAH)
MYB: 102239550(OLAH)
MYD: 102759672(OLAH)
HAI: 109393805(OLAH)
RSS: 109440679 109450692(OLAH)
LAV: 100675942(OLAH)
TMU: 101361105
MDO: 100027206(OLAH)
SHR: 100914322(OLAH)
OAA: 100077700(OLAH)
GGA: 420532(OLAH)
MGP: 100547884(OLAH)
CJO: 107309023(OLAH)
APLA: 101793583(OLAH)
ACYG: 106039692(OLAH)
TGU: 100224799(OLAH)
GFR: 102031766(OLAH)
FAB: 101815966(OLAH)
PHI: 102106226(OLAH)
PMAJ: 107198685(OLAH)
CCAE: 111924181(OLAH)
CCW: 104689201(OLAH)
FPG: 101922325(OLAH)
FCH: 102058635(OLAH)
CLV: 102084717(OLAH)
EGZ: 104128444(OLAH)
AAM: 106483605(OLAH)
ASN: 102386110(OLAH)
AMJ: 102557880(OLAH)
PSS: 102454966(OLAH)
CMY: 102930778(OLAH)
CPIC: 101937274(OLAH)
XLA: 108718823(olah.L)
XTR: 407865(olah)
NPR: 108795592(OLAH)
DRE: 568096(olah)
CCAR: 109111875
IPU: 100528864(olah)
AMEX: 103035172(olah)
TRU: 101061874(olah)
LCO: 104928057(olah)
MZE: 101474377(olah)
OLA: 101160493(olah)
XMA: 102216960(olah)
PRET: 103473026(olah)
NFU: 107394887(olah)
KMR: 108228836(olah)
CSEM: 103393954(olah)
LCF: 108899375(olah)
SDU: 111230514(olah)
HCQ: 109513606(olah)
BPEC: 110168928(olah)
MALB: 109958738(olah)
SASA: 100196232(olah)
OTW: 112264938(olah)
ELS: 105009858(olah)
SFM: 108933393(olah)
LCM: 102354603(OLAH)
CMK: 103181559(olah)
SPU: 582714
CRG: 105339010
MYI: 110445787
EPA: 110234691
ATH: AT1G08510(FATB)
ALY: ARALYDRAFT_888084(FATB)
CRB: 17897852
CPAP: 110823017
LJA: Lj0g3v0119999.1(Lj0g3v0119999.1) Lj1g3v1498440.1(Lj1g3v1498440.1) Lj1g3v1498440.2(Lj1g3v1498440.2)
JCU: 105634942(FAT-L2) 105634943(FAT-L3) 105639285
NNU: 104592290
DOSA: Os02t0644700-01(Os02g0644700) Os06t0143400-01(Os06g0143400) Os06t0596300-01(Os06g0596300) Os11t0659500-01(Os11g0659500)
ATS: 109747972(LOC109747972) 109761208(LOC109761208)
PEN: PSEEN2139
SDE: Sde_3728
BAM: Bamb_6482
DDE: Dde_1605
XAU: Xaut_1005
MET: M446_0169
PRI: PRIO_0771
LLK: LLKF_1167(ylfFG)
LLT: CVCAS_1113(ylfFG)
LLS: lilo_1043
LLC: LACR_1253
LLM: llmg_1415
LLR: llh_6315
LLW: kw2_1088
LLJ: LG36_1240(ylfFG)
LGR: LCGT_0882
LGV: LCGL_0903
SPY: SPy_1042
SPYA: A20_0807(ylfFG)
SPS: SPs1179
SPF: SpyM50993
STG: MGAS15252_0793(fatA)
STX: MGAS1882_0789(fatA)
SPYH: L897_03990
SPN: SP_1408
SPD: SPD_1239
SPR: spr1265
SPW: SPCG_1396
SJJ: SPJ_1307
SPX: SPG_1349
SNT: SPT_0866
SND: MYY_0882
SPNN: T308_03990
SPV: SPH_1539
SPP: SPP_1427
SNP: SPAP_1439
SAG: SAG0891
SAN: gbs0908
SAK: SAK_1014
SGC: A964_0896
SAGM: BSA_9790
SAGI: MSA_10390
SAGR: SAIL_10350
SAGP: V193_04240
SAGC: DN94_04240
SAGE: EN72_05190
SAGG: EN73_04895
SAGN: W903_0982
SMU: SMU_1417c
SMUA: SMUFR_1230
STC: str1235
STL: stu1235
STE: STER_1215
STN: STND_1187
STW: Y1U_C1152
STHE: T303_07115
SSA: SSA_1076
SSI: SSU1263
SUP: YYK_06055
SSUY: YB51_6435
SSUT: TL13_1251
SSUI: T15_1458
SGO: SGO_1328
SEZ: Sez_1208
SEQ: SZO_07520
SEQU: Q426_03070
SEU: SEQ_1394
SUB: SUB1087
SDS: SDEG_1235
SDA: GGS_1119
SDC: SDSE_1211
SGT: SGGB_1446
SMB: smi_0721
SOR: SOR_0721
STK: STP_0942
STB: SGPB_1351
SCF: Spaf_1242
STJ: SALIVA_0834(fat)
SMN: SMA_1450
SIF: Sinf_1259
SIE: SCIM_0723
SIB: SIR_0879
SIU: SII_0896
SANG: SAIN_0781
SANC: SANR_0885
SANS: DK43_06180
SCG: SCI_1032
SCON: SCRE_0973
SCOS: SCR2_0973
SIK: K710_0795
SLU: KE3_1341
STRN: SNAG_0682
LPL: lp_0708
LPJ: JDM1_0584(fat)
LPS: LPST_C0539(fat)
LPZ: Lp16_0558
LJO: LJ_0432
LJH: LJP_0412
LAC: LBA0386
LAD: LA14_0382
LAF: SD55_0383
LSA: LCA_0345
LSL: LSL_1220
LSI: HN6_01008
LSJ: LSJ_1200c
LDB: Ldb1626
LBU: LBUL_1506
LDL: LBU_1387
LBR: LVIS_0609
LCA: LSEI_2254
LPAP: LBPC_2185
LCB: LCABL_24360(fat)
LCS: LCBD_2433
LCE: LC2W_2415
LGA: LGAS_0377
LRE: Lreu_0335
LRF: LAR_0324
LRT: LRI_1603
LHE: lhv_0409
LHL: LBHH_0363
LHV: lhe_1698
LHH: LBH_0330
LHD: HUO_02930
LFE: LAF_0292
LFR: LC40_0208
LFF: LBFF_0311
LRH: LGG_02257(fat)
LRG: LRHM_2169
LRL: LC705_02244(fat)
LRA: LRHK_2253
LAM: LA2_02005
LBH: Lbuc_1367
LKE: WANG_0083
LRM: LRC_05930
LSN: LSA_04860
LAE: LBAT_0447
PPE: PEPE_1476
PPEN: T256_07290
PCE: PECL_504(fat)
EFA: EF0365
EFL: EF62_0698
EFS: EFS1_0250
EFQ: DR75_2357
EFU: HMPREF0351_12195(fat)
EFM: M7W_2204
EHR: EHR_07655
ECAS: ECBG_00012
EMU: EMQU_0686(fat)
EDU: LIU_11930
MPS: MPTP_1782
MPX: MPD5_0284
THL: TEH_09530
OOE: OEOE_1403
LME: LEUM_0283
LMM: MI1_01165
LMK: LMES_0227
LCI: LCK_01510(fat)
LKI: LKI_06955
WKO: WKK_04350
WCE: WS08_1104
WCT: WS74_1172
CML: BN424_499(fat)
CARC: NY10_1348
CTC: CTC_00119
CKL: CKL_0088
ESR: ES1_26570
ESU: EUS_25740
FPR: FP2_08050
FPA: FPR_28760
HAU: Haur_3974
AGL: PYTT_2377
AFD: Alfi_2758
ASH: AL1_28690
MPW: MPR_2035
 » show all
Taxonomy
Reference
1  [PMID:1989513]
  Authors
Pollard MR, Anderson L, Fan C, Hawkins DJ, Davies HM.
  Title
A specific acyl-ACP thioesterase implicated in medium-chain fatty acid production in immature cotyledons of Umbellularia californica.
  Journal
Arch Biochem Biophys 284:306-12 (1991)
DOI:10.1016/0003-9861(91)90300-8
Reference
2  [PMID:1898097]
  Authors
Davies HM, Anderson L, Fan C, Hawkins DJ.
  Title
Developmental induction, purification, and further characterization of 12:0-ACP thioesterase from immature cotyledons of Umbellularia californica.
  Journal
Arch Biochem Biophys 290:37-45 (1991)
DOI:10.1016/0003-9861(91)90588-A
Other DBs
ExplorEnz - The Enzyme Database: 3.1.2.21
IUBMB Enzyme Nomenclature: 3.1.2.21
ExPASy - ENZYME nomenclature database: 3.1.2.21
BRENDA, the Enzyme Database: 3.1.2.21
CAS: 137903-37-8

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