KEGG   ENZYME: 3.1.21.4
Entry
EC 3.1.21.4                 Enzyme                                 

Name
type II site-specific deoxyribonuclease;
type II restriction enzyme
Class
Hydrolases;
Acting on ester bonds;
Endodeoxyribonucleases producing 5'-phosphomonoesters
Reaction(IUBMB)
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates
Comment
This is a large group of enzymes which, together with those now listed as EC 3.1.21.3 (type 1 site-specific deoxyribonuclease) and EC 3.1.21.5.
History
EC 3.1.21.4 created 1984 from EC 3.1.23 and EC 3.1.24
Orthology
K01155  type II restriction enzyme
K21512  terminase, large subunit
Genes
ECD: ECDH10B_1347(2)
ECE: Z1883
ECS: ECs1630
ECF: ECH74115_1620 ECH74115_1783
ETW: ECSP_1536 ECSP_1681 ECSP_2602
ELX: CDCO157_1071 CDCO157_1562 CDCO157_2020 CDCO157_2523
EOI: ECO111_2576
EOJ: ECO26_0602 ECO26_0869 ECO26_1140 ECO26_1954 ECO26_2243 ECO26_2635
EOH: ECO103_0538 ECO103_0779 ECO103_2085 ECO103_2250 ECO103_2392
ECOO: ECRM13514_0554 ECRM13514_0829 ECRM13514_1121 ECRM13514_1822 ECRM13514_2553
ECP: ECP_1167
EBL: ECD_10036(A)
EBE: B21_00731(A)
EBD: ECBD_2873
ESE: ECSF_1069
ELW: ECW_m1703
ELL: WFL_08355
ELF: LF82_161
SENI: CY43_13905
SEC: SCH_1215(terL)
SENB: BN855_9800
SENE: IA1_05065
SFX: S0737
SFV: SFV_2716
SFE: SFxv_0766
SFN: SFy_0950
SFS: SFyv_0989
SSN: SSON_2430
EAR: CCG30840
SPE: Spro_2042
PSTW: DSJ_26575
HIN: HI_0512
PAEM: U769_21795
PAEL: T223_06675
PKC: PKB_5029
POJ: PtoMrB4_23370(A)
PAR: Psyc_0143(dpnC)
PALI: A3K91_0184
PSYC: DABAL43B_0175(dpnC)
PSYA: AOT82_1635
AGU: AS4_28080
MCT: MCR_0519
SDN: Sden_3252
SFR: Sfri_1675
SBL: Sbal_3601
SPSW: Sps_05133
GPS: C427_2420
AMED: B224_1725
ACAV: VI35_08990
NME: NMB0726 NMB1032(nlaIVR) NMB1289 NMB1896(dpnC)
NMA: NMA1499
NMN: NMCC_0324(drg)
NCI: NCTC10296_01548(drg)
RPI: Rpic_1724
RME: Rmet_6120(copL)
BCEO: I35_1510
TAT: KUM_0834
RFR: Rfer_4209
PNA: Pnap_4564
AJS: Ajs_2679
DAC: Daci_4687
DSU: Dsui_1063
TCL: Tchl_2834
HPD: KHP_0260
HPYR: K747_09995
HPYI: K750_02880
HAC: Hac_0519(mjaVIP)
HCE: HCW_04935
HCP: HCN_0370
COJ: CORN_0104
ACLO: ACLO_0529
ACAA: ACAN_0934
ARC: ABLL_1425
SDL: Sdel_1531
GEO: Geob_2517
DFL: DFE_1742
DPS: DP1576
DOL: Dole_3089
XAU: Xaut_4599
MDI: METDI1340
MCH: Mchl_1009
MPO: Mpop_2541
CAK: Caul_2312
SAL: Sala_2432
GOH: B932_3248
GXY: GLX_30330
GXL: H845_3472
SEPS: DP17_55
GHA: NCTC10459_00255(mboIR)
PSAB: PSAB_12850
SPN: SP_1221 SP_1222 SP_1850(dpnC)
SPR: spr1665(dpnC)
SPW: SPCG_1824(dpnC)
SJJ: SPJ_1755
SPX: SPG_1733(dpnB)
SNT: SPT_1767
SND: MYY_1745
SPNN: T308_08385
SPV: SPH_1964
SPP: SPP_1848
SNP: SPAP_1844
SNU: SPNA45_00401(dpnC)
SMU: SMU_506
SMUA: SMUFR_0436
SDS: SDEG_0953
SDA: GGS_0921
SMB: smi_0526
SANC: SANR_0703
SANS: DK43_06655
SRQ: SR187_8185(dpnII)
CSR: Cspa_c40500(dpnB)
AOE: Clos_1062
CTH: Cthe_1512
ESU: EUS_22060
ROB: CK5_08200
ERT: EUR_02470
PHX: KGNDJEFE_00423(dpnB)
THX: Thet_0507
TIT: Thit_0486
TKI: TKV_c04880(mjaIIIR)
CHY: CHY_2211
MED: MELS_0976
MAL: MAGa2710
MCD: MCRO_0752
MFR: MFE_01240(dpnII)
MFM: MfeM64YM_0146(dpnII)
MFP: MBIO_0191
MSS: MSU_0849(dpnII)
MCOU: NCTC10179_00204(dpnB)
PAL: PA0777(rsrIR)
NZS: SLY_1011
ACL: ACL_1082(dpnII)
APAL: BN85400320(dpnII)
MAR: MAE_08660
ANA: all3631(avaIR)
ATM: ANT_07640
DGE: Dgeo_2577
BRM: Bmur_0842
TLI: Tlie_0307
BFR: BF2023
BVU: BVU_3992
PGN: PGN_1425
PDI: BDI_3253
FPS: FP2273(hpaIIR)
FJO: Fjoh_3075
ZPR: ZPR_4244
RAT: M949_0441
IAL: IALB_2630
HTH: HTH_0222
FNO: Fnod_0526
MJA: MJ_0600
MEB: Abm4_1017
METH: MBMB1_0501
 » show all
Reference
1  [PMID:2159140]
  Authors
Roberts RJ.
  Title
Restriction enzymes and their isoschizomers.
  Journal
Nucleic Acids Res 18 Suppl:2331-65 (1990)
DOI:10.1093/nar/18.suppl.2331
Other DBs
ExplorEnz - The Enzyme Database: 3.1.21.4
IUBMB Enzyme Nomenclature: 3.1.21.4
ExPASy - ENZYME nomenclature database: 3.1.21.4
BRENDA, the Enzyme Database: 3.1.21.4
CAS: 9075-08-5

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