KEGG   ENZYME: 3.1.3.26Help
Entry
EC 3.1.3.26                 Enzyme                                 

Name
4-phytase;
6-phytase (name based on 1L-numbering system and not 1D-numbering);
phytase;
phytate 6-phosphatase;
myo-inositol-hexakisphosphate 6-phosphohydrolase (name based on 1L-numbering system and not 1D-numbering)
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
myo-inositol-hexakisphosphate 4-phosphohydrolase
Reaction(IUBMB)
myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,3,5,6-pentakisphosphate + phosphate [RN:R03372]
Reaction(KEGG)
Substrate
myo-inositol hexakisphosphate [CPD:C01204];
H2O [CPD:C00001]
Product
1D-myo-inositol 1,2,3,5,6-pentakisphosphate [CPD:C04579];
phosphate [CPD:C00009]
History
EC 3.1.3.26 created 1972, modified 1976, modified 2002
Pathway
ec00562  Inositol phosphate metabolism
Orthology
K01093  4-phytase / acid phosphatase
Genes
ECO: b0980(appA)
ECJ: JW0963(appA)
ECD: ECDH10B_1050(appA)
EBW: BWG_0832(appA)
ECOK: ECMDS42_0832(appA)
ECE: Z1397(appA)
ECS: ECs1136
ECF: ECH74115_1216(appA)
ETW: ECSP_1149(appA)
ELX: CDCO157_1101
EOJ: ECO26_1535(appA)
EOI: ECO111_1091(appA)
EOH: ECO103_1025(appA)
ECOO: ECRM13514_1157(appA)
ECOH: ECRM13516_1086(appA)
ECG: E2348C_0965(appA)
EOK: G2583_1215(appA)
ESO: O3O_08855
ESM: O3M_16415
ESL: O3K_16440
ECW: EcE24377A_1096(appA)
ELH: ETEC_1049
ECC: c1121(appA)
ECP: ECP_0985
ECI: UTI89_C1049(appA)
ECV: APECO1_84(appA)
ECX: EcHS_A1089(appA)
ECM: EcSMS35_2136(appA)
ECY: ECSE_1042
ECR: ECIAI1_1021(appA)
ECQ: ECED1_1064(appA)
ECK: EC55989_1088(appA)
ECT: ECIAI39_2166(appA)
EOC: CE10_1008(appA)
EUM: ECUMN_1170(appA)
ECZ: ECS88_1002(appA)
ELO: EC042_1065(appA)
ESE: ECSF_0894
EBR: ECB_00983(appA)
EBD: ECBD_2614
EKF: KO11_17825(appA)
EAB: ECABU_c10140(appA)
EDJ: ECDH1ME8569_0932(appA)
EIH: ECOK1_1042(appA)
ENA: ECNA114_1060(appA)
ELW: ECW_m1091(appA)
ELL: WFL_05315(appA)
ELC: i14_1025(appA)
ELD: i02_1025(appA)
ELP: P12B_c0967(appA)
EBL: ECD_00983(appA)
EBE: B21_00990(appA)
ELF: LF82_0100(appA)
ECOI: ECOPMV1_01011(appA_1)
ECOJ: P423_05380
ECOS: EC958_1185(appA)
EFE: EFER_3043
EAL: EAKF1_ch0429c(appA)
SFL: SF0982(appA)
SFX: S1048(appA)
SFV: SFV_0989(appA)
SFE: SFxv_1064(appA)
SFN: SFy_1341
SFS: SFyv_1383
SFT: NCTC1_01020(appA_1)
SSN: SSON_0987(appA)
SBO: SBO_2250(appA)
SBC: SbBS512_E2335(appA)
SDY: SDY_0956(appA)
ESA: ESA_02095
CSK: ES15_2251(appA)
CTU: CTU_18700(appA)
KPN: KPN_00628
KPU: KP1_1578
KPP: A79E_3612
KPT: VK055_1906(phyK)
KPE: KPK_3948
KPR: KPR_3951
KPJ: N559_3698
KPX: PMK1_02960(agp_1)
KPNU: LI86_18965
KPNK: BN49_1685 BN49_4737(appA)
KVA: Kvar_3740
KOX: KOX_14030
KOE: A225_1624
EAE: EAE_02525
EAR: CCG33480
HDE: HDEF_2244(appA)
YPE: YPO1648
YPK: y1810(appA)
YPA: YPA_1875
YPN: YPN_1982
YPM: YP_1778(appA)
YPG: YpAngola_A2841(appA)
YPZ: YPZ3_2046
YPD: YPD4_2087
YPX: YPD8_2084
YPW: CH59_189(appA)
YPJ: CH55_223(appA)
YPV: BZ15_1903(appA)
YPL: CH46_3477(appA)
YPS: YPTB2421
YPO: BZ17_30(appA)
YPI: YpsIP31758_1622(appA)
YPY: YPK_1730
YPB: YPTS_2503
YPQ: DJ40_4145(appA)
YPU: BZ21_1712(appA)
YPR: BZ20_3780(appA)
YPC: BZ23_1998(appA)
YPF: BZ19_1789(appA)
YEN: YE2600
YEY: Y11_14891
YEW: CH47_1942(appA)
YET: CH48_3266(appA)
YAL: AT01_51(appA)
YFR: AW19_831(appA)
YIN: CH53_3517(appA)
YKR: CH54_831
YRO: CH64_183(appA)
SMAF: D781_3671
ECA: ECA4198
PATR: EV46_20920
PATO: GZ59_42580
PCT: PC1_3998
PEC: W5S_4347
DDQ: DDI_4181
EBI: EbC_09720(appa)
PAM: PANA_0959(agp)
PLF: PANA5342_3343(phyK)
PAJ: PAJ_0285(agp)
PVA: Pvag_0342(phyK)
PSTW: DSJ_05650
TPTY: NCTC11468_02898(appA)
ETR: ETAE_1316
ETD: ETAF_1224
ETE: ETEE_3291(appA)
PSHI: SAMEA2665130_1541(appA_4)
XCC: XCC0760(appA)
XCB: XC_3473
XCP: XCR_0938
XCV: XCV0590(appA) XCV0864(appA) XCV4225
XAC: XAC0557(appA) XAC0812(appA) XAC4132(appA)
XCI: XCAW_00167(appA) XCAW_03768(appA)
XOO: XOO3792(appA)
XOM: XOO3574(XOO3574)
XOP: PXO_04687
XOR: XOC_0877
XAL: XALC_2788
XPH: XppCFBP6546_07375(XppCFBP6546P_07375) XppCFBP6546_08950(XppCFBP6546P_08950) XppCFBP6546_13775(XppCFBP6546P_13775)
PSB: Psyr_4500
LHK: LHK_03226
PPNO: DA70_12870
PPNM: LV28_17830
PSPU: NA29_08045
PAPI: SG18_25920
OFO: BRW83_1278(appA_1) BRW83_1307(appA_2)
GUR: Gura_1189
LIP: LI0438
LIR: LAW_00452
AVI: Avi_0609
AZC: AZC_4319
CCR: CC_0542
CCS: CCNA_00576(oppA)
ZMO: ZMO0061
ZMN: Za10_1128
ZMM: Zmob_0756
ZMB: ZZ6_1138
ZMI: ZCP4_1165
ZMC: A265_01156(appA)
ZMR: A254_01155(appA)
SMAZ: LH19_12560
GOX: GOX1076
GOH: B932_1054
GOY: GLS_c11450(appA)
KEU: S101446_02698(appA)
APK: APA386B_1808(appA)
ASZ: ASN_1924(appA)
MHAD: B586_02085
ACA: ACP_1579
ABAS: ACPOL_3731
 » show all
Taxonomy
Reference
1  [PMID:4310376]
  Authors
Johnson LF, Tate ME.
  Title
The structure of myo-inositol pentaphosphates.
  Journal
Ann N Y Acad Sci 165:526-32 (1969)
DOI:10.1111/j.1749-6632.1970.tb56420.x
Reference
2  [PMID:13921788]
  Authors
TOMLINSON RV, BALLOU CE.
  Title
Myoinositol polyphosphate intermediates in the dephosphorylation of phytic acid by phytase.
  Journal
Biochemistry 1:166-71 (1962)
Reference
3  [PMID:4349266]
  Authors
Lim PE, Tate ME.
  Title
The phytases. II. Properties of phytase fractions F 1  and F 2  from wheat bran and the myoinositol phosphates produced by fraction F 2 .
  Journal
Biochim Biophys Acta 302:316-28 (1973)
DOI:10.1016/0005-2744(73)90160-5
Reference
4
  Authors
Cosgrove, D.J.
  Title
Inositol Phosphates: Their Chemistry, Biochemistry, and Physiology, Elsevier, Amsterdam, 1980.
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.26
IUBMB Enzyme Nomenclature: 3.1.3.26
ExPASy - ENZYME nomenclature database: 3.1.3.26
BRENDA, the Enzyme Database: 3.1.3.26
CAS: 9001-89-2

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