| Entry |
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| Name |
nucleotidase;
nucleotide phosphatase;
nucleotide-specific phosphatase;
NSP I;
NSP II;
deoxyribonucleoside-activated nucleotidase (DAN);
deoxyinosine-activated nucleotidase (DIAN);
acid nucleotidase
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| Class |
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
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| Sysname |
nucleotide phosphohydrolase
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| Reaction(IUBMB) |
a nucleotide + H2O = a nucleoside + phosphate [RN: R01572]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
A wide specificity for 2', 3'- and 5'- nucleotides; also hydrolyses glycerol phosphate and 4-nitrophenyl phosphate.
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| History |
EC 3.1.3.31 created 1972 (EC 3.1.3.30 created 1972, incorporated 1992)
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| Reference |
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| Authors |
Arsenis C, Touster O. |
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| Title |
Purification and properties of an acid nucleotidase from rat liver lysosomes. |
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| Journal |
J Biol Chem 243:5702-8 (1968) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.1.3.31 |
| ExPASy - ENZYME nomenclature database: | 3.1.3.31 |
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