KEGG   ENZYME: 3.1.3.49Help
Entry
EC 3.1.3.49                 Enzyme                                 

Name
[pyruvate kinase]-phosphatase;
pyruvate kinase phosphatase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
[ATP:pyruvate 2-O-phosphotransferase]-phosphate phosphohydrolase
Reaction(IUBMB)
[pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate [RN:R03993]
Reaction(KEGG)
Substrate
[pyruvate kinase] phosphate [CPD:C03808];
H2O [CPD:C00001]
Product
[pyruvate kinase] [CPD:C02601];
phosphate [CPD:C00009]
Comment
Simultaneously dephosphorylates and activates EC 2.7.1.40 pyruvate kinase, that has been inactivated by protein kinase.
History
EC 3.1.3.49 created 1984
Reference
1  [PMID:6271587]
  Authors
Jett MF, Hue L, Hers HG.
  Title
Pyruvate kinase phosphatase.
  Journal
FEBS Lett 132:183-6 (1981)
DOI:10.1016/0014-5793(81)81156-8
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.49
IUBMB Enzyme Nomenclature: 3.1.3.49
ExPASy - ENZYME nomenclature database: 3.1.3.49
BRENDA, the Enzyme Database: 3.1.3.49
CAS: 79986-25-7

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