KEGG   ENZYME: 3.1.3.84Help
Entry
EC 3.1.3.84                 Enzyme                                 

Name
ADP-ribose 1''-phosphate phosphatase;
POA1;
Appr1p phosphatase;
Poa1p;
ADP-ribose 1''-phosphate phosphohydrolase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
ADP-D-ribose 1''-phosphate phosphohydrolase
Reaction(IUBMB)
ADP-D-ribose 1''-phosphate + H2O = ADP-D-ribose + phosphate
Substrate
ADP-D-ribose 1''-phosphate;
H2O [CPD:C00001]
Product
ADP-D-ribose [CPD:C00301];
phosphate [CPD:C00009]
Comment
The enzyme is highly specific for ADP-D-ribose 1''-phosphate. Involved together with EC 3.1.4.37, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, in the breakdown of adenosine diphosphate ribose 1'',2''-cyclic phosphate (Appr>p), a by-product of tRNA splicing.
History
EC 3.1.3.84 created 2011
Orthology
K15529  ADP-ribose 1''-phosphate phosphatase
Genes
SCE: YBR022W(POA1)
LTH: KLTH0A01892g
VPO: Kpol_1037p48
ZRO: ZYRO0A04070g
CGR: CAGL0B04411g
NCS: NCAS_0A10220(NCAS0A10220)
NDI: NDAI_0A07250(NDAI0A07250)
TPF: TPHA_0A04210(TPHA0A04210)
TBL: TBLA_0I01770(TBLA0I01770)
KAF: KAFR_0F02400(KAFR0F02400)
CAL: CAALFM_C501200WA(CaO19.1950)
CAUR: QG37_08047
MGR: MGG_10088
CMT: CCM_02762
PTE: PTT_15013
 » show all
Taxonomy
Reference
1  [PMID:15684411]
  Authors
Shull NP, Spinelli SL, Phizicky EM
  Title
A highly specific phosphatase that acts on ADP-ribose 1''-phosphate, a metabolite of tRNA splicing in Saccharomyces cerevisiae.
  Journal
Nucleic Acids Res 33:650-60 (2005)
DOI:10.1093/nar/gki211
  Sequence
[sce:YBR022W]
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.84
IUBMB Enzyme Nomenclature: 3.1.3.84
ExPASy - ENZYME nomenclature database: 3.1.3.84
BRENDA, the Enzyme Database: 3.1.3.84

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