KEGG   ENZYME: 3.1.30.2Help
Entry
EC 3.1.30.2                 Enzyme                                 

Name
Serratia marcescens nuclease;
endonuclease (Serratia marcescens);
barley nuclease;
plant nuclease I;
nucleate endonuclease
Class
Hydrolases;
Acting on ester bonds;
Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters
BRITE hierarchy
Reaction(IUBMB)
Endonucleolytic cleavage to 5'-phosphomononucleotide and 5'-phosphooligonucleotide end-products
Comment
Hydrolyses double- or single-stranded substrate.
History
EC 3.1.30.2 created 1965 as EC 3.1.4.9, transferred 1978 to EC 3.1.30.2, modified 1981
Reference
1  [PMID:4319109]
  Authors
Mikulski AJ, Laskowski M Sr.
  Title
Mung bean nuclease I. 3. Purification procedure and (3') omega monophosphatase activity.
  Journal
J Biol Chem 245:5026-31 (1970)
Reference
2
  Authors
Stevens, A. and Hilmoe, R.J.
  Title
Studies on a nuclease from Azotobacter agilis. I. Isolation and mode of action.
  Journal
J Biol Chem 235:3016-3022 (1960)
Reference
3
  Authors
Stevens, A. and Hilmoe, R.J.
  Title
Studies on a nuclease from Azotobacter agilis. II. Hydrolysis of ribonucleic and deoxyribonucleic acids.
  Journal
J Biol Chem 235:3023-3027 (1960)
Reference
4  [PMID:4296679]
  Authors
Wechter WJ, Mikulski AJ, Laskowski M Sr.
  Title
Gradation of specificity with regard to sugar among nucleases.
  Journal
Biochem Biophys Res Commun 30:318-22 (1968)
DOI:10.1016/0006-291X(68)90453-1
Other DBs
ExplorEnz - The Enzyme Database: 3.1.30.2
IUBMB Enzyme Nomenclature: 3.1.30.2
ExPASy - ENZYME nomenclature database: 3.1.30.2
BRENDA, the Enzyme Database: 3.1.30.2
CAS: 9025-65-4

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