KEGG   ENZYME: 3.1.31.1Help
Entry
EC 3.1.31.1                 Enzyme                                 

Name
micrococcal nuclease;
spleen endonuclease;
thermonuclease;
nuclease T;
micrococcal endonuclease;
nuclease T';
staphylococcal nuclease;
spleen phosphodiesterase;
Staphylococcus aureus nuclease;
Staphylococcus aureus nuclease B;
ribonucleate (deoxynucleate) 3'-nucleotidohydrolase
Class
Hydrolases;
Acting on ester bonds;
Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters
BRITE hierarchy
Reaction(IUBMB)
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products
Comment
Hydrolyses double- or single-stranded substrate.
History
EC 3.1.31.1 created 1961 as EC 3.1.4.7, transferred 1978 to EC 3.1.31.1, modified 1981
Orthology
K01174  micrococcal nuclease
Genes
DHA: DEHA2D04950g
PIC: PICST_29232
PGU: PGUG_04999
KPY: KPNIH31_26665
KQV: B8P98_28620
EBI: EbC_32160
MDN: JT25_004580
TAO: THIAE_06255
NOC: Noc_1218 Noc_1464
TBN: TBH_C2685
HAR: HEAR3042
HCP: HCN_1935
CJE: Cj0979c
CJU: C8J_0918
CJI: CJSA_0922
CJS: CJS3_1029
CJEJ: N564_00946
CJEU: N565_00993
CJEN: N755_00985
CJEI: N135_01016
CJER: H730_05780
CJY: QZ67_01053(nucH)
CJQ: UC78_0937(nucH)
CJR: CJE1061
CLA: Cla_0563
CCQ: N149_0916
CCF: YSQ_04125
CCY: YSS_05310
CCOI: YSU_04160
CCOF: VC76_04750(nucH)
CCOO: ATE51_01664(nucH)
CIS: CINS_0485
CVO: CVOL_0500
CPEL: CPEL_0518
CGRA: CGRAC_1875
CCUN: CCUN_0740
CAVI: CAV_0451
SULJ: SJPD1_1195
PCA: Pcar_2433
DEU: DBW_3159
DAS: Daes_0648
DPI: BN4_12369
PPRF: DPRO_2172
DRT: Dret_1889
MXA: MXAN_0570
SCL: sce7025
BBA: Bd1934
BBAT: Bdt_1907
BBAC: EP01_05720
BSU: BSU21610(yokF)
BSR: I33_1967
BSL: A7A1_3318
BSH: BSU6051_17620(yncB) BSU6051_21610(yokF)
BSUT: BSUB_01894(yncB) BSUB_02325(yokF)
BSUL: BSUA_01894(yncB) BSUA_02325(yokF)
BSUS: Q433_10390
BSS: BSUW23_09040(yncB)
BST: GYO_2117
BSO: BSNT_08334(yncB)
BSQ: B657_17620(yncB) B657_21610(yokF)
BSX: C663_1818(yncB)
BAQ: BACAU_1985(nucB3)
BYA: BANAU_1709(yokF)
BAMP: B938_10245
BAML: BAM5036_1910(yokF)
BAMA: RBAU_1946(yokF) RBAU_2164
BAMB: BAPNAU_1563(nuc) BAPNAU_1750(yokF)
BAMT: AJ82_11250
BAMY: V529_21730
BMP: NG74_02073(yokF)
BAO: BAMF_1818(nuc)
BQL: LL3_02390(nuc)
BQY: MUS_1922(yokF)
BATR: TD68_06010
BAI: BAA_A0216
BANT: A16_60530
BANR: A16R_61550
BANV: DJ46_5623
BCA: BCE_A0141
BCQ: BCQ_PI098
BCX: BCA_A0204
BNC: BCN_P258
BCER: BCK_27193
BMQ: BMQ_2840
BMD: BMD_2874
BMEG: BG04_5380(yncB)
BCK: BCO26_2125(yokF)
BAG: Bcoa_2359
BCOA: BF29_1224(yokF) BF29_2488(yokF) BF29_2564(yokF)
BJS: MY9_1920
BACP: SB24_18790
BACO: OXB_3577
BACL: BS34A_19500(yncB) BS34A_23830(yokF)
BALM: BsLM_1865
BGY: BGLY_3147
BKW: BkAM31D_16040(yncB)
ANM: GFC28_493
AAMY: GFC30_1816(yokF)
LSP: Bsph_1248
SAU: SA0746 SA1160(nuc)
SAV: SAV0815(nuc) SAV1324(nuc)
SAW: SAHV_0811(nuc) SAHV_1313(nuc)
SAM: MW0769 MW1211(nuc)
SAR: SAR0847(nuc) SAR1334(nucI)
SAC: SACOL0860(nuc) SACOL1357
SAE: NWMN_0760 NWMN_1236(nuc)
SAD: SAAV_0761(nuc) SAAV_1303
SUE: SAOV_0832(nuc) SAOV_1337(nucI)
SUZ: MS7_0843(nuc) MS7_1283(nucH)
SAUS: SA40_0730(nuc) SA40_1203(nucI)
SAUU: SA957_0745(nuc) SA957_1218(nucI)
SAUG: SA268_0744(nuc) SA268_1223(nucI)
SAB: SAB0748(nuc) SAB1182(nucI)
SAUB: C248_0884(nuc) C248_1358(nucI)
SAUC: CA347_1263(nucH) CA347_810(nuc)
SAUI: AZ30_06440
SEP: SE1004
SER: SERP0891
SEPP: SEB_01029
SEPS: DP17_2330(nucH)
SHA: SH1583(nuc) SH1688
SSP: SSP1444
SCA: SCA_0025(nuc) SCA_0963(nuc)
SLN: SLUG_15760(nucI)
SDT: SPSE_1449(nucA) SPSE_1452(nucB) SPSE_2407(nucC)
SPAS: STP1_2353
SXO: SXYL_01562(nuc)
SHU: SHYC_07780(nuc)
SCAP: AYP1020_0535(nuc) AYP1020_0632(nucH)
SSCZ: RN70_07580
MCL: MCCL_1810
MCAK: MCCS_18890(nuc_1) MCCS_23490(nuc_2)
ESI: Exig_0209
EAN: Eab7_0198
GMO: NCTC11323_00754(yncB)
PMW: B2K_27260
PSWU: SY83_15545
ASOC: CB4_02102(nucH_1) CB4_02227(nucH_2) CB4_03174(yokF_2)
AAC: Aaci_0018
BTS: Btus_1737
SIV: SSIL_3210
EFA: EF0511(nuc-1) EF_B0045(nuc-2)
EFL: EF62_pB0046(pcfT) EF62_pC0033(pcfT)
EFQ: DR75_3002(yncB)
CRN: CAR_c07670(yokF)
CARC: NY10_59
CBL: CLK_A0066
CBB: CLD_A0131
CBI: CLJ_0002
CPAT: CLPA_c04520(nucH)
CPAE: CPAST_c04520(nucH)
CSQ: CSCA_0087
CTYK: CTK_C11500
ASF: SFBM_0242
BPB: bpr_II283
BFI: CIY_18770
EAC: EAL2_808p06360(nucH)
FAA: HMPREF0389_00861(nucH)
STH: STH2345
DAU: Daud_0794
TMR: Tmar_1711
CTHM: CFE_1921
CHY: CHY_1644(nucH1) CHY_1699(nucH2)
ADG: Adeg_1341
FMA: FMG_P0127
PED: ING2D1G_0444(nucH)
ERH: ERH_1180
MPU: MYPU_1390(MYPU_1390)
MMO: MMOB1270(nuc)
MHJ: MHJ_0262
MSY: MS53_0110
MAA: MAG0790
MAL: MAGa0850
MHO: MHO_0660
MCD: MCRO_0604
MHR: MHR_0255
MHH: MYM_0330
MHM: SRH_00660
MHS: MOS_286
MHV: Q453_0360
MFR: MFE_01650
MFP: MBIO_0232
MBH: MMB_0081
MBI: Mbov_0087(nuc)
MCY: MCYN_0708(MCYN0708)
MCAN: MCAN360_0524(snc)
MARG: MARG145_0665(snc)
MBJ: KQ51_00354(nucH)
ASD: AS9A_1464
CGL: NCgl1779(Cgl1853)
CGU: WA5_1779
CGV: CGLAU_07765(nucH)
RHU: A3Q40_03369(nucH)
GBR: Gbro_4927
GOR: KTR9_5325
ARM: ART_3810
DCO: SAMEA4475696_0605(nucH)
NDK: I601_0037(nucH) I601_1605(nuc)
MMAR: MODMU_4087
TBI: Tbis_0133
RXY: Rxyl_2044
CWO: Cwoe_5232
GPA: GPA_22130
CYA: CYA_1940
CYB: CYB_0109(nucH)
CYL: AA637_01785(nuc)
GEN: GM3709_54
TER: Tery_0755
ANA: all2918
NAZ: Aazo_0889
CALH: IJ00_00690
CTHE: Chro_0331
RCA: Rcas_0199
CAU: Caur_0552
TRA: Trad_2390
TTR: Tter_2736
PSL: Psta_2998
PLS: VT03_05060(nucH)
PLH: VT85_11270(nuc)
FMR: Fuma_01279(nucH)
TTF: THTE_3660
GES: VT84_06390(nucH)
PBOR: BSF38_02094(nuc_1) BSF38_05072(nuc_2)
KST: KSMBR1_0031(nucI)
LBA: Lebu_1478
TLI: Tlie_1879
SBR: SY1_02080
DORI: FH5T_14940
LBY: Lbys_2496
FBA: FIC_01092
BPI: BPLAN_500(lpxP)
BMM: MADAR_477(lpxP)
CACI: CLOAM1654
AAE: aq_710(nucI)
HTH: HTH_0636(nuc)
TAL: Thal_1226
TLE: Tlet_1208
THER: Y592_03670
FNO: Fnod_0753
DTN: DTL3_0506
KOL: Kole_0136
MOX: DAMO_1702
SRG: XF24_00953(nucH)
MJA: MJ_1439
MMP: MMP1201
MMD: GYY_06835
MAE: Maeo_0569
MVO: Mvol_0962
METC: MTCT_0425
METE: tca_00458(nuc)
MEYE: TL18_06955
METH: MBMB1_0301
MFC: BRM9_1971
MCUB: MCBB_0554(nucI)
GAH: GAH_01015
PHO: PH1212(PH1212)
PAB: PAB0704
PFU: PF1298
PFI: PFC_05705
PYN: PNA2_1734
PYS: Py04_0910
TGA: TGAM_1824(nuc)
THE: GQS_01590
THA: TAM4_275
TEU: TEU_05670
MMET: MCMEM_0129
MMH: Mmah_1858
MCJ: MCON_2244
HHB: Hhub_2325
HALH: HTSR_1259
HHSR: HSR6_1332
HMA: rrnAC3140(nuc)
HHI: HAH_0406(nuc)
HUT: Huta_1665
HTI: HTIA_1390
HMU: Hmuk_1261
HWA: HQ_3375A
HWC: Hqrw_3898
HME: HFX_1541(nuc)
NMR: Nmar_1467
TAA: NMY3_00683(nuc)
NBV: T478_0082
 » show all
Taxonomy
Reference
1  [PMID:13860347]
  Authors
ALEXANDER M, HEPPEL LA, HURWITZ J.
  Title
The purification and properties of micrococcal nuclease.
  Journal
J Biol Chem 236:3014-9 (1961)
Reference
2
  Authors
Anfinsen, C.B., Cuatrecasas, P. and Taniuchi, H.
  Title
Staphylococcal nuclease, chemical properties and catalysis.
  Journal
In: Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 4, Academic Press, New York, 1971, p. 177-204.
Reference
3
  Authors
Reddi, K.K.
  Title
Micrococcal nuclease.
  Journal
Methods Enzymol 12A:257-262 (1967)
Reference
4  [PMID:5922962]
  Authors
Sulkowski E, Laskowski M Sr.
  Title
Phosphatase-free crystalline micrococcal nuclease.
  Journal
J Biol Chem 241:4386-8 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 3.1.31.1
IUBMB Enzyme Nomenclature: 3.1.31.1
ExPASy - ENZYME nomenclature database: 3.1.31.1
BRENDA, the Enzyme Database: 3.1.31.1
CAS: 9013-53-0

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