KEGG ENZYME: 3.1.4.44

ENZYME: 3.1.4.44

Entry

EC 3.1.4.44                 Enzyme

Name

glycerophosphoinositol glycerophosphodiesterase;
sn-glycero(3)phosphoinositol glycerophosphohydrolase;
sn-glycero-3-phospho-1-inositol glycerophosphohydrolase

Class

Hydrolases;
Acting on ester bonds;
Phosphoric-diester hydrolases

Sysname

1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase

Reaction(IUBMB)

1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = myo-inositol + sn-glycerol 3-phosphate [RN:R01193]

Reaction(KEGG)

R01193

Substrate

1-(sn-glycero-3-phospho)-1D-myo-inositol [CPD:C01225];
H2O [CPD:C00001]

Product

myo-inositol [CPD:C00137];
sn-glycerol 3-phosphate [CPD:C00093]

History

EC 3.1.4.44 created 1984, modified 2002

Orthology

K19179

glycerophosphoinositol glycerophosphodiesterase

Genes

HSA:	51573(GDE1)

PTR:	453968(GDE1)

PPS:	100982724(GDE1)

GGO:	134757492(GDE1)

PON:	100449346(GDE1)

PPYG:

129015715(GDE1)

NLE:	100606291(GDE1)

HMH:	116471095(GDE1)

SSYN:

129493187(GDE1)

MCC:	694849(GDE1)

MCF:	102143508(GDE1)

MTHB:

126945066

MNI:	105484970(GDE1)

CSAB:

103229117(GDE1)

CATY:

105586721(GDE1)

PANU:

101011648(GDE1)

TGE:	112614063(GDE1)

MLEU:

105536658(GDE1)

RRO:	104682063(GDE1)

RBB:	108513802(GDE1)

TFN:	117087547(GDE1)

PTEH:

111551173(GDE1)

CANG:

105504428(GDE1)

CJC:	100412182(GDE1)

SBQ:	101044732(GDE1)

CIMI:

108308466(GDE1)

ANAN:

105725563(GDE1)

CSYR:

103264599(GDE1)

MMUR:

105855213(GDE1)

LCAT:

123632435(GDE1)

PCOQ:

105812988(GDE1)

OGA:	100955864(GDE1)

MMU:	56209(Gde1)

MCAL:

110297754(Gde1)

MPAH:

110324830(Gde1)

RNO:	60418(Gde1)

MCOC:

116102855(Gde1)

ANU:	117724751(Gde1)

MUN:	110555529(Gde1)

CGE:	100750723(Gde1)

MAUA:

101835599(Gde1)

PROB:

127228241(Gde1)

PLEU:

114692145(Gde1)

MORG:

121457593(Gde1)

MFOT:

126502339

AAMP:

119799979(Gde1)

NGI:	103742777(Gde1)

HGL:	101701542(Gde1)

CPOC:

100734943(Gde1)

CCAN:

109684166(Gde1)

DORD:

105982228(Gde1)

DSP:	122096279(Gde1)

PLOP:

125340901(Gde1)

NCAR:

124970708 124974078

MMMA:

107146533(Gde1)

OCU:

100353916

OPI:	101521804(GDE1)

TUP:	102491967(GDE1)

GVR:	103599883(GDE1)

CFA:	479827(GDE1) 482696

CLUD:

112640313(GDE1)

VVP:	112923366(GDE1)

VLG:	121486835(GDE1)

NPO:	129519527(GDE1)

AML:	100465615(GDE1)

UMR:	103668649(GDE1)

UAH:	113254586(GDE1)

UAR:	123775580(GDE1)

ELK:

111156120

LLV:

125090665

MPUF:

101694378(GDE1)

MNP:	132026862(GDE1)

MLK:	131820111(GDE1)

NVS:	122895435(GDE1)

ORO:	101373098(GDE1)

EJU:	114199674(GDE1)

ZCA:	113931816(GDE1)

MLX:	118021880(GDE1)

NSU:	110587844(GDE1)

LWW:	102750757(GDE1)

FCA:	101085681(GDE1)

PYU:	121019451(GDE1)

PCOO:

112853363(GDE1)

PBG:	122471610(GDE1)

PVIV:

125154526(GDE1)

LRUF:

124517836

PTG:	102967328(GDE1)

PPAD:

109278404(GDE1)

PUC:

125927932

AJU:

106970466

HHV:	120247836(GDE1)

BTA:	539978(GDE1)

BOM:	102277876(GDE1)

BIU:	109578708(GDE1)

BBUB:

102389197(GDE1)

BBIS:

104986527(GDE1)

CHX:	102177211(GDE1)

OAS:	101117209(GDE1)

BTAX:

128068022(GDE1)

CSUM:

138076477(GDE1)

ODA:	120875325(GDE1)

CCAD:

122433365(GDE1)

MREE:

136160569(GDE1)

MBEZ:

129545417(GDE1)

SSC:	100624000(GDE1)

CFR:	102522959(GDE1)

CBAI:

105073719(GDE1)

CDK:	105091141(GDE1)

VPC:	102532711(GDE1)

BACU:

103004264(GDE1)

BMUS:

118881340(GDE1)

LVE:	103090181(GDE1)

OOR:	101289947(GDE1)

DLE:	111163523(GDE1)

PCAD:

102992535(GDE1)

PSIU:

116740354(GDE1)

NASI:

112399433(GDE1)

ECB:	100050012(GDE1)

EPZ:	103563941(GDE1)

EAI:	106839019(GDE1)

MYB:	102251727(GDE1)

MYD:	102759065(GDE1)

MMYO:

118656059(GDE1)

MLF:	102420854(GDE1)

MDT:	132233136(GDE1)

PKL:	118702899(GDE1)

EFUS:

103286075(GDE1)

MNA:	107524368(GDE1)

DRO:	112314853(GDE1)

SHON:

119001992(GDE1)

AJM:	119055026(GDE1)

PDIC:

114494513(GDE1)

PHAS:

123806321(GDE1)

MMF:	118642199(GDE1)

PPAM:

129083725(GDE1)

HAI:	109395683(GDE1)

RFQ:	117019705(GDE1)

PALE:

102887417(GDE1)

PGIG:

120620458(GDE1)

PVP:	105303735(GDE1)

RAY:	107516855(GDE1)

MJV:	108393708(GDE1)

TOD:	119241877(GDE1)

SARA:

101557137(GDE1)

SETR:

126030920(GDE1)

LAV:	100666577(GDE1)

TMU:

101346039

ETF:	101640178(GDE1)

DNM:	101436920(GDE1)

MDO:	100018844(GDE1)

GAS:	123234504(GDE1)

SHR:	100926896(GDE1)

AFZ:

127564903

PCW:	110193451(GDE1)

TVP:	118834105 118834400(GDE1)

PBRV:

138167334(GDE1)

OAA:	100078062(GDE1)

GGA:	416612(GDE1)

PCOC:

116237408(GDE1)

MGP:	100545694(GDE1)

CJO:	107320851(GDE1)

TPAI:

128078898(GDE1)

LMUT:

125700548(GDE1)

NMEL:

110406015(GDE1)

APLA:

101789588(GDE1)

ACYG:

106033467(GDE1)

CATA:

118249193(GDE1)

AFUL:

116495100(GDE1)

TGU:	100218434(GDE1)

LSR:	110475553(GDE1)

SCAN:

103817696(GDE1)

PMOA:

120512878(GDE1)

OTC:	121334504(GDE1)

PRUF:

121350810(GDE1)

GFR:	102037817(GDE1)

FAB:	101806703(GDE1)

OMA:	130259329(GDE1)

PHI:	102105484(GDE1)

PMAJ:

107211053(GDE1)

CCAE:

111935991(GDE1)

CCW:	104685065(GDE1)

CBRC:

103615629(GDE1)

ACOE:

138118536(GDE1)

ETL:	114058245(GDE1)

ZAB:	102069766(GDE1)

ZLE:	135454323(GDE1)

ACHL:

103808241(GDE1)

SVG:	106848787(GDE1)

MMEA:

130584270(GDE1)

HRT:	120759704(GDE1)

SATI:

136367828(GDE1)

FPG:	101924240(GDE1)

FCH:	102046551(GDE1)

CCRI:

104155490(GDE1)

SHAB:

115606546(GDE1)

ACUN:

113485673(GDE1)

TALA:

104366132(GDE1)

ACHC:

115335567(GDE1)

HALD:

104322629(GDE1)

HLE:	104833688(GDE1)

AGEN:

126034249

HHAR:

128134566(GDE1)

GCL:

127022199

CSTI:

104551342(GDE1)

LDI:	104349219(GDE1)

MNB:	103774547(GDE1)

DPUB:

104299499(GDE1)

PPUS:

135180963(GDE1)

AVIT:

104267236(GDE1)

BRHI:

104502362(GDE1)

EGZ:	104135874(GDE1)

NNI:	104015035(GDE1)

PCRI:

104024894(GDE1)

PCAO:

104052953(GDE1)

PADL:

103917641(GDE1)

AFOR:

103900900(GDE1)

FGA:	104070253(GDE1)

GSTE:

104255788(GDE1)

CLV:	102086236(GDE1)

MUI:	104543385(GDE1)

PGUU:

104464071(GDE1)

PLET:

104625912(GDE1)

EHS:	104516759(GDE1)

CMAC:

104486876(GDE1)

CUCA:

104063812(GDE1)

TEO:	104370348(GDE1)

OHA:	104333697(GDE1)

ACAR:

104528151(GDE1)

CPEA:

104393782(GDE1)

CVF:	104287868(GDE1)

RTD:	128913632(GDE1)

AAM:	106491347(GDE1)

AROW:

112974242(GDE1)

NPD:	112959974(GDE1)

TGT:	104568567(GDE1)

DNE:	112990404(GDE1)

SCAM:

104149753(GDE1)

ASN:	102385931(GDE1)

AMJ:	102566034(GDE1)

CPOO:

109314561(GDE1)

GGN:	109294463(GDE1)

PSS:	102451429(GDE1)

CMY:	102942535(GDE1)

CCAY:

125644373(GDE1)

DCC:	119862073(GDE1)

CPIC:

101930875(GDE1)

TST:	117883912(GDE1)

CABI:

116836530(GDE1)

MRV:	120373135(GDE1)

ACS:	100561993(gde1)

ASAO:

132781824(GDE1)

PVT:	110083995(GDE1)

SUND:

121914499(GDE1)

PBI:	103060652(GDE1)

PMUR:

107296936(GDE1)

CTIG:

120315712(GDE1)

TSR:	106553263(GDE1)

PGUT:

117670802(GDE1)

APRI:

131185190(GDE1)

PTEX:

113452433 113452436

NSS:	113429132(GDE1)

VKO:	123025057(GDE1)

PMUA:

114584189(GDE1)

PRAF:

128401447(GDE1)

ZVI:	118093145(GDE1)

HCG:	128336437(GDE1)

GJA:	107114591(GDE1)

EMC:	129338437(GDE1)

XLA:	495935(gde1.L)

XTR:	549927(gde1)

NPR:	108788650(GDE1)

RTEM:

120943530(GDE1)

BBUF:

121008575(GDE1)

BGAR:

122945844(GDE1)

MUO:	115476737(GDE1)

GSH:	117369083(GDE1)

DRE:	393213(gde1)

SRX:	107742094 107755351

SANH:

107655362 107659316

SGH:	107566046 107566664

CCAR:

109088889 109088902

CAUA:

113039960 113065058

CGIB:

127943082 127988306

PTET:

122327681(gde1)

LROH:

127153469(gde1)

OMC:	131531154(gde1)

PPRM:

120495389(gde1)

RKG:	130103534(gde1)

MAMB:

125263714(gde1)

CIDE:

127520679

CERY:

137027826(gde1)

MASI:

127438530 127438954

TROS:

130549015(gde1)

TDW:	130430595(gde1)

MANU:

129453692(gde1)

IPU:

108259438

IFU:	128603021(gde1)

PHYP:

113547591(gde1)

SMEO:

124380039(gde1)

TFD:	113657056(gde1)

TVC:	132838934(gde1)

TRN:	134304160(gde1)

AMEX:

103041835(gde1)

CMAO:

118804584(gde1)

EEE:	113580701(gde1)

CHAR:

105896885(gde1)

TRU:	101068713 101077926

TFS:	130515480 130527767(gde1)

TNG:	GSTEN00026230G001

LCO:	104922018 109138266

NCC:	104960149(gde1) 104965604

TBEN:

117474597(gde1) 117493242

CGOB:

115010669 115011778

PGEO:

117451552 117466537(gde1)

GACU:

117548528 117561609(gde1)

EMAC:

134864902(gde1) 134878559

ELY:	117254554(gde1) 117268052

EFO:	125879372 125886073(gde1)

PLEP:

121942179(gde1) 121957067

SLUC:

116042986(gde1) 116059297

ECRA:

117934792(gde1) 117957867

ESP:	116697941 116702730

PFLV:

114547034(gde1) 114570074

GAT:	120825139(gde1) 120827744

PPUG:

119218411(gde1) 119220517

AFB:	129096306(gde1) 129098975

CLUM:

117735340 117736430(gde1)

PSWI:

130189638(gde1)

CANA:

137786786 137795261(gde1)

CVE:	137878648 137885282(gde1)

MSAM:

119881829 119899426(gde1)

SCHU:

122868814 122874116(gde1)

CUD:	121503837 121509035(gde1)

ALAT:

119014117 119021469(gde1)

ASTR:

137600134(gde1) 137610032

MZE:	101468031 101475968

ONL:	100697703 100700294

OAU:	116310605(gde1) 116321413

OLA:	101157842(gde1)

OML:	112137438(gde1)

CSAI:

133444092(gde1)

XMA:	102217533(gde1)

XCO:	114144846(gde1)

XHE:	116720146(gde1)

PRET:

103464417(gde1)

PFOR:

103131037(gde1)

PLAI:

106945960(gde1)

PMEI:

106933948(gde1)

GAF:	122829732(gde1)

PPRL:

129366946(gde1)

CVG:

107083412

CTUL:

119787519(gde1)

GMU:	124868488(gde1)

NFU:	107390598(gde1)

KMR:	108241433(gde1)

ALIM:

106532040(gde1)

NWH:	119422761(gde1)

AOCE:

111569917(gde1) 111587536

EJA:	138198016 138208810(gde1)

MCEP:

124997451 125001352(gde1)

CSEM:

103384083 103392994(gde1)

POV:	109627710 109643717

SSEN:

122770604(gde1) 122782713 122784752

HHIP:

117761490(gde1) 117765885

HSP:	118098011(gde1) 118123078

PPLT:

128437181(gde1) 128458883

SMAU:

118289465 118312155(gde1)

LCF:	108885401(gde1) 108886163

SDU:	111227166 111229231

SLAL:

111665537 111667494

XGL:	120784998 120799981(gde1)

HCQ:	109527513(gde1)

SSCV:

125969252(gde1)

SBIA:

133506419(gde1)

PEE:	133403545(gde1)

PTAO:

133476282(gde1)

BPEC:

110166208(gde1) 110169834

MALB:

109972281 109972905

BSPL:

114851866(gde1) 114860927

SJO:	128378390 128379361(gde1)

SASA:

106564457 106589785 106590471 106606508 106606516

STRU:

115147395 115171771 115177853 115206416

OTW:	112226267 112238363(gde1)

OMY:	110485529 110485530 110487014 110487023

OGO:	124000077 124015552(gde1)

ONE:	115115810 115116024

OKI:

109876506

OKE:	118371733 118376386(gde1)

SALP:

112077286

SNH:	120017610(gde1) 120044678

CCLU:

121550499 121553831(gde1) 121565814

ELS:	105012113 105021649

SFM:	108928836(gde1)

PKI:	111843206 111860580

AANG:

118217027 118219866

LOC:	102696337(gde1)

PSPA:

121300810(gde1)

ARUT:

117431346(gde1)

PSEX:

120542234(gde1)

LCM:	102349184(GDE1)

CMK:	103178805(gde1)

RTP:	109919805(gde1)

CPLA:

122560912(gde1)

HOC:	132825105(gde1)

LERI:

129706607(gde1)

PMRN:

116946227(GDE1)

LRJ:	133353680(GDE1)

BFO:

118429149

BBEL:

109463335

SPU:	575640 753330

LPIC:

129269376

APLC:

110990301

ARUN:

117293084

SKO:	100366891 102804795

AME:

726389

ACER:

107999538

ALAB:

122712014

ADR:

102677129

AFLR:

100865444

BIM:

100746135

BBIF:

117209570

BVK:

117234489

BVAN:

117158498

BHUN:

126866375

BTER:

100644729

BAFF:

126928689

BPYO:

122571975

BPAS:

132908575

FVI:

122528191

CCAL:

108622996

OBB:

114874560

OLG:

117606891

MGEN:

117219929

NMEA:

116433693

CGIG:

122403342

SOC:

105200203

MPHA:

105830346

AEC:

105153356

ACEP:

105621481

PBAR:

105425290

VEM:

105564243

HST:

105191665

DQU:

106751040

CFO:

105255796

FEX:

115243333

LHU:

105671855

PGC:

109862315

OBO:

105287732

PCF:

106789510

PFUC:

122525021

VPS:

122628141

VCRB:

124423182

VVE:

124948209

NVI:

100678544

CSOL:

105367501

TPRE:

106659586

LHT:

122509116

LBD:

127278405

MDL:

103573164

CGLO:

123266513

FAS:

105270618

DAM:

107040701

AGIF:

122853699

VCAN:

122409551

CCIN:

107275088

DSM:

124406670

NPT:

124214832

NFB:

124178443

NLO:

107227423

NVG:

124300786

AROA:

105688375

TCA:

661873

AGRG:

126736534

ATD:

109603356

CSET:

123318676 123318744

AGB:

108915195

LDC:

111518164

DVV:

114331670

NVL:

108558883

APLN:

108743140

PPYR:

116164425

OTU:

111416267

CCRN:

123297900

BTAB:

109035748

CLEC:

106671126

HHAL:

106686891

NLU:	111059508 120348907 120354117

HVI:

124353863

MQU:

129002113

PHU:	Phum_PHUM020220

FOC:

113217461

TPAL:

117642292

ZNE:

110834478

CSEC:

111874079

BROR:

134534041

IEL:

124165610

FCD:

110849238

EAF:

111704468

LSM:

121114735

TCF:

131882211

PPOI:

119095477 119095481

DSV:	119441049 119449538 119462272 119463697 119463698 119465349

RSAN:

119385314 119385501 119385579 119400465 119401219 119402492

RMP:	119163889 119173740 119177922

VDE:

111246442

VJA:

111260899

CSCU:

111625277

CVS:

136976941

PTEP:

107449558

ABRU:

129975704

UDV:

129228016

SDM:

118201007

LPOL:

106476654 106477621

CEL:	CELE_T12B3.3(T12B3.3) CELE_T22G5.1(T22G5.1) CELE_Y40C5A.4(Y40C5A.4) CELE_ZC155.4(ZC155.4)

CBR:	CBG_05849 CBG_23426 CBG_23963

CRQ:	GCK72_008505 GCK72_013945 GCK72_018241

NAI:	NECAME_14204

BMY:	BM_BM5739(Bm5739)

LOA:	LOAG_12305

HRO:	HELRODRAFT_123455

LGI:	LOTGIDRAFT_228958

PVUL:

126811003

PCAN:

112571396

BGT:

106052557

GAE:

121379263

HRF:

124141155

HASI:

137283744

OBI:

106878131

OSN:

115209731

LJP:

135469539

NVE:

5520233

EPA:

110238708

ATEN:

116298015

ADF:	107346891 107346920

AMIL:

114958246 114958247

MCAZ:

138058960 138058962

PDAM:

113684347 113684349

SPIS:

111334012 111334018

DGT:

114519301

XEN:

124448045

HMG:	100215468 105849368

HSY:

130614268

RES:

135691858

TAD:	TRIADDRAFT_52925

AQU:	100636249 100638012

» show all

Reference

1 [PMID:40550]

Authors

Dawson RM, Hemington N, Richards DE, Irvine RF.

Title

sn-Glycero(3)phosphoinositol glycerophosphohydrolase. A new phosphodiesterase in rat tissues.

Journal

Biochem J 182:39-49 (1979)
DOI:10.1042/bj1820039

Other DBs

ExplorEnz - The Enzyme Database:

3.1.4.44

IUBMB Enzyme Nomenclature:

3.1.4.44

ExPASy - ENZYME nomenclature database:

3.1.4.44

BRENDA, the Enzyme Database:

3.1.4.44

CAS:	72414-13-2

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