KEGG   ENZYME: 3.1.6.1Help
Entry
EC 3.1.6.1                  Enzyme                                 

Name
arylsulfatase;
sulfatase;
nitrocatechol sulfatase;
phenolsulfatase;
phenylsulfatase;
p-nitrophenyl sulfatase;
arylsulfohydrolase;
4-methylumbelliferyl sulfatase;
estrogen sulfatase
Class
Hydrolases;
Acting on ester bonds;
Sulfuric-ester hydrolases
BRITE hierarchy
Sysname
aryl-sulfate sulfohydrolase
Reaction(IUBMB)
a phenol sulfate + H2O = a phenol + sulfate [RN:R01243]
Reaction(KEGG)
R01243 > R03980;
(other) R04856 R06280(G)
Show
Substrate
phenol sulfate [CPD:C00850];
H2O [CPD:C00001]
Product
phenol [CPD:C15584];
sulfate [CPD:C00059]
Comment
A group of enzymes with rather similar specificities.
History
EC 3.1.6.1 created 1961, modified 2011
Pathway
ec00140  Steroid hormone biosynthesis
ec00600  Sphingolipid metabolism
Orthology
K01130  arylsulfatase
Genes
KLA: KLLA0F03146g
KMX: KLMA_60006 KLMA_80180
LTH: KLTH0E16610g
ZRO: ZYRO0G03476g
DHA: DEHA2F16412g
PIC: PICST_37138(ARS1)
PGU: PGUG_01192
SPAA: SPAPADRAFT_154340
LEL: LELG_02036
CAL: CAALFM_C302360CA(CaO19.1608)
CAUR: QG37_05114
MGR: MGG_10308
ANI: AN6847.2
ANG: ANI_1_2238074(An08g08530) ANI_1_860014(An01g06640)
PBN: PADG_11756(PADG_04380)
ABE: ARB_00994
TVE: TRV_03742
MRR: Moror_848
ECO: b3801(aslA)
ECJ: JW3773(aslA)
ECD: ECDH10B_3991(aslA)
EBW: BWG_3480(aslA)
ECOK: ECMDS42_3240(aslA)
ECE: Z5314(aslA)
ECS: ECs4731
ECF: ECH74115_5237(aslA)
ETW: ECSP_4852(aslA)
ECG: E2348C_4099(aslA)
EOK: G2583_4596(aslA)
ECC: c4719(aslA)
ECP: ECP_3993
ECI: UTI89_C4359(aslA)
ECV: APECO1_2677(aslA)
ECM: EcSMS35_4166(aslA)
ECQ: ECED1_4484(aslA)
ECT: ECIAI39_2989(aslA)
EOC: CE10_4445(aslA)
EUM: ECUMN_4324(aslA)
ECZ: ECS88_4222(aslA)
ELO: EC042_4175(aslA)
ESE: ECSF_3638
EBR: ECB_03676(aslA)
EBD: ECBD_4241
EDJ: ECDH1ME8569_3680(aslA)
EIH: ECOK1_4248(aslA)
ENA: ECNA114_3936(aslA)
ELC: i14_4312(aslA)
ELD: i02_4312(aslA)
EBL: ECD_03676(aslA)
EBE: B21_03625(aslA)
ELF: LF82_0162(aslA)
ECOI: ECOPMV1_04135(atsA_2)
ECOJ: P423_21035
ECOO: ECRM13514_4863(aslA)
ECOH: ECRM13516_4647(aslA)
ECOS: EC958_4260(aslA)
EFE: EFER_3705(aslA)
STM: STM3122
SENI: CY43_16275
SEI: SPC_3189
SEC: SCH_3062(ars)
SHB: SU5_03620
SED: SeD_A3466
SEG: SG3016
SEL: SPUL_3125
SET: SEN2965
SENA: AU38_15070
SENO: AU37_15080
SENV: AU39_15075
SENQ: AU40_16990
SENL: IY59_15680
SEEP: I137_14935
SENE: IA1_15070
SDY: SDY_3945(aslA)
KPN: KPN_00527
KPU: KP1_1453
KPP: A79E_3723
KPT: VK055_2016(atsA)
KPR: KPR_4030(atsA)
KPJ: N559_3813
KPX: PMK1_02857(atsA)
KPNU: LI86_19545
KPNK: BN49_1574(atsA)
EBF: D782_4351
SMAF: D781_0561
SMAR: SM39_4950(atsA)
SMAC: SMDB11_4693(atsA)
SERF: L085_01235
PSI: S70_17830
PSX: DR96_2521(atsA)
PRG: RB151_036750(atsA_1) RB151_041280(atsA_2)
ETE: ETEE_0993(aslA)
SACZ: AOT14_07700(atsA)
VSC: VSVS12_03950(aslA)
VTA: B0163
PAE: PA0183(atsA)
PAEV: N297_188(atsA)
PAEI: N296_188(atsA)
PAU: PA14_02310(atsA)
PAG: PLES_01841(atsA)
PAF: PAM18_0183(atsA)
PNC: NCGM2_0191(atsA)
PAEB: NCGM1900_0176(atsA)
PAEP: PA1S_00955
PAEM: U769_00940
PAEL: T223_00925
PAEU: BN889_00236(atsA)
PAEG: AI22_02970
PAEC: M802_187(atsA)
PAEO: M801_188(atsA)
PCQ: PcP3B5_17400(atsA_1) PcP3B5_23580(atsA_2) PcP3B5_33010(atsA_3)
PPU: PP_3352(atsA)
PPF: Pput_2406
PPX: T1E_5507(atsA)
PFL: PFL_0205(atsA) PFL_2842
PPRC: PFLCHA0_c02060(atsA)
PPRO: PPC_0213(atsA)
PFS: PFLU_0198(atsA)
PMAN: OU5_1064 OU5_5920(arsA)
PSTT: CH92_04300
PSOS: POS17_0211(atsA)
ACB: A1S_0977
ABM: ABSDF2424(atsA)
ABY: ABAYE2815(atsA)
ABN: AB57_1056
ABX: ABK1_0964
ABH: M3Q_1276
ABAD: ABD1_09310(atsA)
ABAA: IX88_06905
ACC: BDGL_000257(atsA) BDGL_000399(atsA) BDGL_001196(atsA)
ACI: ACIAD1598(atsA)
SSE: Ssed_3990
SPL: Spea_1735
SHL: Shal_1886
PSPO: PSPO_b0409(aslA) PSPO_b1470(aslA)
AMAD: I636_19365
AMAI: I635_20205
AMAG: I533_19100
GPS: C427_5016
FBL: Fbal_0804
MICC: AUP74_00205(atsA_1) AUP74_01034(atsA_2) AUP74_02154(atsA_3) AUP74_02743(betC) AUP74_02746(atsA_4) AUP74_02747(atsA_5)
FTU: FTT_0783(ars)
FTF: FTF0783(ars)
TIG: THII_2781
ADI: B5T_01497(atsA)
AVR: B565_2058
REH: H16_A1602(h16_A1602) H16_B0315(h16_B0315) H16_B0483(h16_B0483)
RME: Rmet_5416(aslA) Rmet_5423(atsA)
BCJ: BCAM0569
BCEN: DM39_4592(atsA)
BCEW: DM40_3633(atsA)
BCEO: I35_4464
BAM: Bamb_5276
BMU: Bmul_5130
BMK: DM80_4308(atsA)
BMUL: NP80_3587
BCED: DM42_4521(atsA)
BDL: AK34_4843
BCON: NL30_22950
BUB: BW23_4289
BLAT: WK25_20755
BTEI: WS51_01445
BSEM: WJ12_22845
BPSL: WS57_11020
BMEC: WJ16_21860
BSTG: WT74_21870
BGP: BGL_2c14430(atsA)
BGO: BM43_5191(atsA)
BXE: Bxe_A2132
BXB: DR64_4287
BPH: Bphy_5555
BPE: BP1635
BPC: BPTD_1615
BPER: BN118_1608
BPET: B1917_1577
BPEU: Q425_18300
BPA: BPP2750
BPAR: BN117_3763
BBR: BB2736
AXX: ERS451415_03680(atsA)
PUT: PT7_1854
AFQ: AFA_05705
VEI: Veis_1030
DAC: Daci_3115
LIM: L103DPR2_02521(atsA_2)
LIH: L63ED372_01166(atsA_1)
MPT: Mpe_A2680
MMS: mma_2412(aslA1) mma_2424(aslA2) mma_2430(aslA3)
CFU: CFU_0042(atsA)
CPRA: CPter91_0041(atsA)
TIN: Tint_1572
RGE: RGE_25260
AZA: AZKH_1948
DBA: Dbac_1085
CCX: COCOR_01295(atsA) COCOR_02875(atsA1) COCOR_06442(aslA) COCOR_06451(aslA1)
SCL: sce7731(atsA)
BBAT: Bdt_1434
BBAC: EP01_03500
MLO: mll5471
PLA: Plav_2014
EAD: OV14_a0303(betC) OV14_b0389(betC)
ARA: Arad_7826
AOL: S58_30160
RPD: RPD_1640
NHA: Nham_2976
MNO: Mnod_8070
MOR: MOC_3700
MSL: Msil_3123
HDN: Hden_2940
RVA: Rvan_3560
RBM: TEF_15265
PZU: PHZ_c0420(atsA)
SIL: SPO3286(atsA)
DSH: Dshi_0936 Dshi_3111(aslA)
PGA: PGA1_c21300(atsA)
PGL: PGA2_c01650(atsA)
MALG: MALG_01285
HNE: HNE_2211
SAL: Sala_0299
SGI: SGRAN_0977(atsA) SGRAN_1166(atsA2)
STAX: MC45_15920
SSY: SLG_10610
SPHR: BSY17_3614
SINB: SIDU_15105
ADO: A6F68_00846(atsA_3)
BMYC: DJ92_3892
PMW: B2K_22760
PSWU: SY83_12440
MTU: Rv0663(atsD) Rv0711(atsA) Rv3299c(atsB)
MTC: MT0692 MT0738(atsA) MT3398
MRA: MRA_0673(atsD) MRA_0719(atsA) MRA_3340(atsB)
MTUR: CFBS_0695(atsD) CFBS_0747(atsA) CFBS_3490(atsB)
MTO: MTCTRI2_0679(atsD) MTCTRI2_0727(atsA)
MTD: UDA_0663(atsD) UDA_0711(atsA) UDA_3299c(atsB)
MTN: ERDMAN_0733(atsD) ERDMAN_0783(atsA) ERDMAN_3615(atsB)
MTUT: HKBT1_0695(atsD) HKBT1_0747(atsA) HKBT1_3477(atsB)
MTUU: HKBT2_0696(atsD) HKBT2_0748(atsA) HKBT2_3484(atsB)
MTQ: HKBS1_0695(atsD) HKBS1_0747(atsA) HKBS1_3487(atsB)
MBB: BCG_0712(atsD) BCG_0761(atsA) BCG_3328c(atsB) BCG_3364c(atsB_2)
MBT: JTY_0682(atsD) JTY_0731(atsA) JTY_3324(atsB_1)
MBM: BCGMEX_0683(atsD) BCGMEX_0732(atsA) BCGMEX_3326c(atsB_1) BCGMEX_3361c(atsB_2)
MAF: MAF_06720(atsD) MAF_33100(atsB)
MCE: MCAN_06621(atsD) MCAN_07161(atsA) MCAN_33221(atsB)
MCQ: BN44_10727(atsD) BN44_10787(atsA) BN44_70090(atsB)
MCV: BN43_20090(atsD) BN43_20149(atsA) BN43_60315(atsB)
MCX: BN42_20413(atsD) BN42_20468(atsA) BN42_41357(atsB)
MCZ: BN45_10758(atsD) BN45_10815(atsA) BN45_60337(atsB)
MPA: MAP_4171(atsA)
MAO: MAP4_4296
MAVI: RC58_21340
MAVU: RE97_21390
MUL: MUL_0227(aslA) MUL_0454(atsD) MUL_2500(atsD_1) MUL_2658(atsB)
MMI: MMAR_1041(atsA) MMAR_1232(atsB) MMAR_1375(atsD_1) MMAR_4410(aslA) MMAR_4950(atsD)
MMAE: MMARE11_08860(atsA_1) MMARE11_12000(atsB) MMARE11_13420(atsD_1) MMARE11_27600(atsD_2) MMARE11_42350(aslA) MMARE11_47600(atsD)
MLI: MULP_01051(atsA_1) MULP_01173(atsA) MULP_01390(atsB) MULP_05196(atsD)
MPHL: MPHLCCUG_01318(atsA)
MAB: MAB_4307
MABB: MASS_4348
MABO: NF82_21575
MSTE: MSTE_01761(atsA) MSTE_04493
MJD: JDM601_3324(atsA)
MTER: 4434518_03313(atsA)
CGL: NCgl2422(Cgl2508)
CEF: CE1568
CTER: A606_00115
CGY: CGLY_01735(astA)
GOR: KTR9_4079
TPR: Tpau_2981
SBH: SBI_00597
SFI: SFUL_1339
SRW: TUE45_pSRc_0159(atsA)
SFK: KY5_0922c
KSK: KSE_70840
XCE: Xcel_0426
IDO: I598_2332(atsA)
MPH: MLP_26780(atsA) MLP_36410
NDK: I601_2956(atsA)
SEN: SACE_3101(atsD)
PDX: Psed_0727
SESP: BN6_58460
SAQ: Sare_3132
MIL: ML5_3230
SNA: Snas_3261
AYM: YM304_31400(atsA) YM304_37550(atsA)
PMT: PMT_1515
MAR: MAE_60180
MPK: VL20_3667
AVA: Ava_0111
CALH: IJ00_08850
PUV: PUV_21540(Arsa)
OBG: Verru16b_00676(atsA_2)
AMU: Amuc_0565
AGL: PYTT_1429
RBA: RB11116(aslA) RB1477(atsA) RB1610(aslA) RB1736 RB2367 RB2377(atsA) RB3876(arsA) RB3877(aslA) RB607 RB684 RB686 RB7772(atsA) RB9498(arsA) RB9530(aslA)
PIR: VN12_02395(atsA_5) VN12_09245(atsA_10) VN12_09960(atsA_12) VN12_10140(atsA_13)
PLS: VT03_07615(atsA_7) VT03_14665(atsA_12) VT03_23645(atsA_17) VT03_31545(atsA_23)
PLH: VT85_01435(atsA_4) VT85_11950(atsA_9) VT85_23310(atsA_14) VT85_25985(atsA_16) VT85_26500(atsA_17) VT85_26505(atsA_18)
FMR: Fuma_00057(atsA_1) Fuma_01184(atsA_8) Fuma_03524(atsA_19) Fuma_04191(atsA_29) Fuma_05745(atsA_41) Fuma_05847(atsA_43) Fuma_06240(atsA_45) Fuma_06317(atsA_47) Fuma_06320 Fuma_06527(atsA_49)
GES: VT84_34800(atsA_4) VT84_34805(atsA_5)
PBOR: BSF38_02950(atsA_4) BSF38_03154(atsA_5) BSF38_03674(atsA_8) BSF38_04054(atsA_9) BSF38_05270(atsA_11)
PBU: L21SP3_00174(atsA_2) L21SP3_00313(atsA_6) L21SP3_00911(atsA_12) L21SP3_00941(atsA_13) L21SP3_01571(atsA_20) L21SP3_01737(atsA_23) L21SP3_02132(atsA_30) L21SP3_02161(atsA_31)
PBAS: SMSP2_01915(atsA_27) SMSP2_01958(atsA_29)
PBP: STSP1_00013(atsA_1) STSP1_00472(atsA_4) STSP1_00789(atsA_15) STSP1_01016(atsA_18) STSP1_01177(atsA_22) STSP1_01418(atsA_27) STSP1_01857(atsA_40) STSP1_01946(atsA_41)
VBL: L21SP4_00137(atsA_2) L21SP4_00773(atsA_11) L21SP4_00907(atsA_14) L21SP4_02062(atsA_26) L21SP4_02251(atsA_29) L21SP4_02378(atsA_30)
ABAC: LuPra_01391(atsA_5)
BFR: BF0017
BVU: BVU_0394
BXY: BXY_22120
BOA: Bovatus_03187(atsA_4) Bovatus_03601(atsA_7) Bovatus_03634(atsA_10) Bovatus_03636(atsA_11)
FLN: FLA_3285
GFL: GRFL_0295
FJG: BB050_00434(atsA_1) BB050_01459(atsA_2) BB050_02936(atsA_3) BB050_02942(atsA_5) BB050_03442(atsA_6)
ZPR: ZPR_1980
MARM: YQ22_04895
MAC: MA_2645(atsA) MA_2648(atsA) MA_2650(atsA)
MMA: MM_1892
MMAC: MSMAC_1636
MTHE: MSTHC_0313
MTHR: MSTHT_0408
MHOR: MSHOH_1668
MCJ: MCON_2731
MPD: MCP_2347(atsA) MCP_2349
RCI: RCIX63(atsA)
NPH: NP_0946A
HWC: Hqrw_2718
LOKI: Lokiarch_18380(atsA_1) Lokiarch_23360(atsA_2)
 » show all
Taxonomy
Reference
1  [PMID:13363831]
  Authors
DODGSON KS, SPENCER B, WILLIAMS K.
  Title
Studies on sulphatases.  13.  The hydrolysis of substituted phenyl sulphates by the arylsulphatase of Alcaligenes metalcaligenes.
  Journal
Biochem J 64:216-21 (1956)
Reference
2  [PMID:13744184]
  Authors
ROY AB.
  Title
The synthesis and hydrolysis of sulfate esters.
  Journal
Adv Enzymol Relat Subj Biochem 22:205-35 (1960)
Reference
3  [PMID:13772]
  Authors
Roy AB.
  Title
Sulphatases, lysosomes and disease.
  Journal
Aust J Exp Biol Med Sci 54:111-35 (1976)
Reference
4  [PMID:13843260]
  Authors
WEBB EC, MORROW PF.
  Title
The activation of an arysulphatase from ox liver by chloride and other anions.
  Journal
Biochem J 73:7-15 (1959)
Other DBs
ExplorEnz - The Enzyme Database: 3.1.6.1
IUBMB Enzyme Nomenclature: 3.1.6.1
ExPASy - ENZYME nomenclature database: 3.1.6.1
BRENDA, the Enzyme Database: 3.1.6.1
CAS: 9016-17-5

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