KEGG   ENZYME: 3.1.7.6Help
Entry
EC 3.1.7.6                  Enzyme                                 

Name
farnesyl diphosphatase;
FPP phosphatase
Class
Hydrolases;
Acting on ester bonds;
Diphosphoric-monoester hydrolases
BRITE hierarchy
Sysname
(2E,6E)-farnesyl-diphosphate diphosphohydrolase
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-farnesol + diphosphate [RN:R08697]
Reaction(KEGG)
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448];
H2O [CPD:C00001]
Product
(2E,6E)-farnesol [CPD:C01126];
diphosphate [CPD:C00013]
Comment
The enzyme is involved in the biosynthesis of acyclic sesquiterpenoids [1].
History
EC 3.1.7.6 created 2010
Pathway
ec00900  Terpenoid backbone biosynthesis
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K15793  acyclic sesquiterpene synthase
Genes
BDI: 100833760
SBI: 8072328
ZMA: 541974(tps1)
SITA: 101771563
Taxonomy
Reference
1  [PMID:16484724]
  Authors
Song L
  Title
A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol.
  Journal
Appl Biochem Biotechnol 128:149-58 (2006)
Reference
2  [PMID:4288361]
  Authors
Tsai SC, Gaylor JL.
  Title
Testicular sterols. V. Preparation and partial purification of a microsomal prenol pyrophosphate pyrophosphohydrolase.
  Journal
J Biol Chem 241:4043-50 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 3.1.7.6
IUBMB Enzyme Nomenclature: 3.1.7.6
ExPASy - ENZYME nomenclature database: 3.1.7.6
BRENDA, the Enzyme Database: 3.1.7.6

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