KEGG   ENZYME: 3.10.1.1Help
Entry
EC 3.10.1.1                 Enzyme                                 

Name
N-sulfoglucosamine sulfohydrolase;
sulfoglucosamine sulfamidase;
heparin sulfamidase;
2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate sulphohydrolase)
Class
Hydrolases;
Acting on sulfur-nitrogen bonds;
Acting on sulfur-nitrogen bonds (only sub-subclass identified to date)
BRITE hierarchy
Sysname
N-sulfo-D-glucosamine sulfohydrolase
Reaction(IUBMB)
N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate [RN:R01963]
Reaction(KEGG)
R01963;
(other) R07814(G)
Show
Substrate
N-sulfo-D-glucosamine [CPD:C01075];
H2O [CPD:C00001]
Product
D-glucosamine [CPD:C00329];
sulfate [CPD:C00059]
History
EC 3.10.1.1 created 1972, modified 1981, modified 1982
Pathway
ec00531  Glycosaminoglycan degradation
ec01100  Metabolic pathways
Orthology
K01565  N-sulfoglucosamine sulfohydrolase
Genes
HSA: 6448(SGSH)
PTR: 745502(SGSH)
PPS: 100985307(SGSH)
GGO: 101142618(SGSH)
PON: 100459478(SGSH)
NLE: 100588596(SGSH)
MCC: 717977(SGSH)
MCF: 102142565(SGSH)
CSAB: 103243692(SGSH)
RRO: 104675244(SGSH)
RBB: 108534150(SGSH)
CJC: 100411890(SGSH)
SBQ: 101040481(SGSH)
MMU: 27029(Sgsh)
RNO: 688293(Sgsh)
CGE: 100755391(Sgsh)
NGI: 103730575(Sgsh)
HGL: 101720611(Sgsh)
CCAN: 109689941(Sgsh)
TUP: 102473234(SGSH)
CFA: 403707(SGSH)
AML: 100477824(SGSH)
UMR: 103665802(SGSH)
ORO: 101385912(SGSH)
FCA: 101094715(SGSH)
PTG: 102957138(SGSH)
AJU: 106981876(SGSH)
BTA: 535442(SGSH)
BOM: 102274142(SGSH)
BIU: 109574273(SGSH)
PHD: 102320007(SGSH)
CHX: 102175240(SGSH)
OAS: 101121184(SGSH)
SSC: 100737146(SGSH)
CFR: 102511664(SGSH)
CDK: 105106252(SGSH)
BACU: 102997141(SGSH)
LVE: 103089895(SGSH)
OOR: 101289415(SGSH)
ECB: 100056499(SGSH)
EPZ: 103547325(SGSH)
EAI: 106845569(SGSH)
MYB: 102239046(SGSH)
MYD: 102753251(SGSH)
HAI: 109383662(SGSH)
RSS: 109449390(SGSH)
PALE: 102893583(SGSH)
LAV: 100658885(SGSH)
TMU: 101346127
MDO: 100030803(SGSH)
SHR: 100932279(SGSH)
OAA: 100079215(SGSH)
GGA: 422081(SGSH)
MGP: 100549132(SGSH)
CJO: 107322087(SGSH)
ACYG: 106046739(SGSH)
TGU: 100230664(SGSH)
GFR: 102037178(SGSH)
FAB: 101812983(SGSH)
PHI: 102110099(SGSH)
PMAJ: 107212385(SGSH)
CCW: 104698239(SGSH)
FPG: 101918825(SGSH)
FCH: 102050903(SGSH)
CLV: 102090183(SGSH)
EGZ: 104130619(SGSH)
AAM: 106484733 106485998(SGSH)
ASN: 102382451(SGSH)
AMJ: 102576386(SGSH)
PSS: 102460593(SGSH)
CMY: 102940151(SGSH)
CPIC: 101954045(SGSH)
ACS: 100561423(sgsh)
PVT: 110090123(SGSH)
PBI: 103064462(SGSH)
GJA: 107119861(SGSH)
XLA: 495504(sgsh.L)
XTR: 100145064(sgsh)
NPR: 108792969(SGSH)
DRE: 563849(sgsh)
SRX: 107756031
SGH: 107586947(sgsh) 107593085
CCAR: 109047860
IPU: 108259505(sgsh)
AMEX: 103028698(sgsh)
TRU: 101072409(sgsh)
LCO: 104930251(sgsh)
NCC: 104950013(sgsh)
MZE: 101463965(sgsh)
OLA: 101155495(sgsh)
XMA: 102222374(sgsh)
PRET: 103465890(sgsh)
NFU: 107392187(sgsh)
CSEM: 103383950(sgsh) 103383953
LCF: 108875653(sgsh)
HCQ: 109527474(sgsh)
BPEC: 110165214(sgsh) 110165216
SASA: 100195283(sphm) 106564344(SPHM)
ELS: 105012037(sgsh)
SFM: 108930233(sgsh)
LCM: 102349697(SGSH)
CMK: 103175583(sgsh)
DME: Dmel_CG14291(CG14291)
DSI: Dsimw501_GD20144(Dsim_GD20144)
MDE: 101887821
AAG: 5573339
AME: 550884
BIM: 100747363
BTER: 100645767
SOC: 105205194
AEC: 105152566
ACEP: 105621840
PBAR: 105426128
HST: 105188180
CFO: 105249090
LHU: 105667524
PGC: 109858431
NVI: 100119668
TCA: 659261
DPA: 109541348
NVL: 108561271
BMOR: 101737423
PMAC: 106721422
PRAP: 111002361
PXY: 105387712
ZNE: 110832827
MYI: 110448223
OBI: 106867433
EPA: 110255094
ADF: 107348323
AQU: 100638186
SSCK: SPSK_06264
ANG: ANI_1_1460064(An07g01010)
MMED: Mame_02677
MALG: MALG_04863
SSAN: NX02_06935
RBA: RB2135
PLS: VT03_05165(atsA_4)
IPA: Isop_2942
VBL: L21SP4_01486(atsA_23)
FLM: MY04_4254
ZGA: ZOBELLIA_2201(sgsA4)
 » show all
Taxonomy
Reference
1  [PMID:5775690]
  Authors
Dietrich CP.
  Title
Enzymic degradation of heparin. A sulphamidase and a sulphoesterase from Flavobacterium heparinum.
  Journal
Biochem J 111:91-5 (1969)
Reference
2  [PMID:6849981]
  Authors
Mahuran D, Clements P, Hopwood J.
  Title
A rapid four column purification of 2-deoxy-D-glucoside-2-sulphamate sulphohydrolase from human liver.
  Journal
Biochim Biophys Acta 757:359-65 (1983)
DOI:10.1016/0304-4165(83)90062-4
Other DBs
ExplorEnz - The Enzyme Database: 3.10.1.1
IUBMB Enzyme Nomenclature: 3.10.1.1
ExPASy - ENZYME nomenclature database: 3.10.1.1
BRENDA, the Enzyme Database: 3.10.1.1
CAS: 37289-41-1

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