KEGG   ENZYME: 3.2.1.17Help
Entry
EC 3.2.1.17                 Enzyme                                 

Name
lysozyme;
muramidase;
globulin G;
mucopeptide glucohydrolase;
globulin G1;
N,O-diacetylmuramidase;
lysozyme g;
L-7001;
1,4-N-acetylmuramidase;
mucopeptide N-acetylmuramoylhydrolase;
PR1-lysozyme
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
peptidoglycan N-acetylmuramoylhydrolase
Reaction(IUBMB)
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Comment
cf. also EC 3.2.1.14 chitinase.
History
EC 3.2.1.17 created 1961
Orthology
K01185  lysozyme
K11331  cation efflux system protein involved in nickel and cobalt tolerance
K13381  bifunctional chitinase/lysozyme
K13915  lysozyme C
K21509  peptidoglycan hydrolase
Genes
HSA: 119180(LYZL2) 389852(SPACA5) 4069(LYZ) 57151(LYZL6) 729201(SPACA5B) 84569(LYZL1)
PTR: 450190(LYZ) 450382 465613(SPACA5) 468388(LYZL6) 736064
PPS: 100970943(LYZ) 100976701(LYZL1) 100979617 100994594(SPACA5) 100995179(LYZL6)
GGO: 101129337 101130053(LYZL2) 101140406(SPACA5B) 101150696(LYZL6) 109028445
PON: 100436864(LYZL6) 100439578(SPACA5) 100450383(LYZL1) 100451264(LYZ)
NLE: 100580402 100596481(LYZ) 100599455(LYZL6) 100606007(SPACA5) 100607029(LYZD1)
MCC: 693706(LYZL1) 698176(LYZD1) 708435(SPACA5) 716662(LYZL6) 718361(LYZ)
MCF: 101926718(LYZL6) 102116763(SPACA5) 102124401(LYZL1) 102133357 102140636(LYZ)
CSAB: 103231905(SPACA5) 103238064 103238695(LYZ) 103242758(LYZL6) 103247457
RRO: 104657271 104658663(LYZ) 104676523(SPACA5) 104679572(LYZL6)
CJC: 100385827 100393686(LYZ) 100395207(SPACA5) 100410559(LYZL6) 100414530(LYZD1)
MMU: 17105(Lyz2) 17110(Lyz1) 278203(Spaca5) 67328(Lyzl1) 69444(Lyzl6)
RNO: 25211(Lyz2) 287751(Lyzl6) 314431(Spaca5) 364745(Lyzl1) 688047(Lyc2)
OCU: 100340903(LYZ) 100341160(LYZF1) 100342234(LYZE) 100342739(LYZL6) 100356058(LYZD1) 108175363(lysozyme)
CFA: 474442(LYZ) 480492 480901 487083 609038(LYZF2)
AML: 100478101 100480487(SPACA5) 100480842 100482516(LYZ) 105235307(LYZL6)
UMR: 103656494 103656876(LYZ) 103664020(SPACA5) 103665608(LYZL6) 103675441
PTG: 102958733(SPACA5) 102960581(LYZL1) 102965818(GOSR2) 102967785(LYZ) 102972398
BTA: 280849(LYZ2) 281287(LYZ1) 281289(LYZ3) 493637(LYSB) 512087(LYZL1) 517880(SPACA5) 540048(LYZL6) 617219 777776(LYZ) 781146 781349(LYZ1) 785803 787241
SSC: 100157211(LYZ) 100415934(SPACA5) 100517051 100738578(LYZL6)
CFR: 102503823(LYZL6) 102505229(SPACA5) 102506357 102518571(LYZL1) 102519275
BACU: 103000541(SPACA5) 103010320(LYZL1) 103015948 103016960(LYZ)
LVE: 103070714(LYZL1) 103080439(LYZL6) 103080876(LYZ) 103088530(SPACA5)
OOR: 101269824(LYZL1) 101280263 101281258(LYZL6) 101287011(LYZ)
MYB: 102245430(SPACA5) 102250583(LYZL6) 102257440(LYZ)
MYD: 102757557(SPACA5) 102766021 102775207(LYZL6)
SHR: 100920653(LYZ)
OAA: 100076093 100079369(LYZ) 100090093(LYZL6)
GGA: 396218(LYZ)
MGP: 100547044(LYZ)
CJO: 107310471(LYZ)
APLA: 101798606 101804721(LYZ)
ACYG: 106046114 106046934(LYZ)
TGU: 100190600
GFR: 102045253(LYZ)
FAB: 101821950(LYZ)
PHI: 102100687(LYZ)
PMAJ: 107214954(LYZ)
CCW: 104692444(LYZ)
FPG: 101916517(LYZL1) 106112774(LYZ)
FCH: 102051400(LYZ) 102058786(LYZL1)
CLV: 102087273(LYZ)
AAM: 106488400(LYZ) 106500259
XTR: 100492798(lyz) 100493330 448362 496769(spaca5)
DRE: 677744(lyz)
IPU: 100528519(lysc) 108262691
OLA: 100302449(lyz)
XMA: 102230251(lyz) 102235463
NFU: 107375351(lyz)
CSEM: 103389095(lyz)
SASA: 100136365(LYSC2) 106599999(lyz)
SFM: 108929886(lyz) 108939579
DME: Dmel_CG11159(CG11159) Dmel_CG1165(LysS) Dmel_CG1179(LysB) Dmel_CG1180(LysE) Dmel_CG16756(CG16756) Dmel_CG16799(CG16799) Dmel_CG30062(CG30062) Dmel_CG7798(CG7798) Dmel_CG8492(CG8492) Dmel_CG9116(LysP) Dmel_CG9118(LysD) Dmel_CG9120(LysX)
DSI: Dsimw501_GD13493(Dsim_GD13493) Dsimw501_GD13593(Dsim_GD13593) Dsimw501_GD13594(Dsim_GD13594) Dsimw501_GD25258(Dsim_GD25258) Dsimw501_GD25259(Dsim_GD25259) Dsimw501_GD25558(Dsim_GD25558) Dsimw501_GD27298(Dsim_GD27298) Dsimw501_GD27312(Dsim_GD27312) Dsimw501_GD29578(Dsim_GD29578)
AGA: AgaP_AGAP007343(LYSC2) AgaP_AGAP007344(LYSC8) AgaP_AGAP007347(LYSC1_ANOGA) AgaP_AGAP007385(LYSC4)
HST: 105191507
CFO: 105254967
TCA: 100142316 658610(Lyz)
BMOR: 105842620 693015(Lzm)
TUT: 107363126
MAJ: MAA_06197
PBL: PAAG_11876(PAAG_04465)
ABE: ARB_07390
ABP: AGABI1DRAFT24208(AGABI1DRAFT_24208)
ABV: AGABI2DRAFT59492(AGABI2DRAFT_59492)
DFA: DFA_02793
ECO: b0555(rrrD) b1554(rrrQ) b3338(chiA)
ECJ: JW0544(ybcS) JW1546(ydfQ) JW3300(chiA)
EBW: BWG_0427(arrD) BWG_1373(arrQ) BWG_3029(chiA)
ECC: c0957 c1436 c1562(ybcS) c3180 c4109(yheB)
ECY: ECSE_0589
ECR: ECIAI1_0777(ybcS) ECIAI1_1597(ydfQ)
ECQ: ECED1_0888(lys) ECED1_1028(ydfQ) ECED1_1124(ydfQ) ECED1_1430(ydfQ) ECED1_2107(ydfQ) ECED1_2527(ydfQ) ECED1_3082(R) ECED1_3998(chiA)
ECK: EC55989_0784(ybcS) EC55989_1054(ydfQ) EC55989_1384(ydfQ) EC55989_1715(ydfQ) EC55989_2620(ybcS)
EOC: CE10_0525(arrD1) CE10_1045(arrQ1) CE10_1463(arrQ2) CE10_1737 CE10_1819(arrQ3) CE10_2460(arrQ4) CE10_5146(arrD2)
EUM: ECUMN_0606(ybcS) ECUMN_1335(ydfQ) ECUMN_1411(ybcS) ECUMN_1841(ydfQ)
ECZ: ECS88_0562(ydfQ) ECS88_1185(ybcS) ECS88_2828(R) ECS88_3726(chiA) ECS88_5020(ydfQ)
EBR: ECB_00507(ybcS) ECB_00835 ECB_01337(ydfQ-1) ECB_01519(ydfQ-2) ECB_03189(chiA)
ELW: ECW_m0298(lys) ECW_m0929 ECW_m1710(arrQ)
ELC: i14_1313 i14_1397(ybcS) i14_3784(chiA)
ELD: i02_1313 i02_1397(ybcS) i02_3784(chiA)
ELP: P12B_c0752(ybcS) P12B_c1519(ydfQ) P12B_c1867(lycV) P12B_c2734(nucD) P12B_c3440(chiA)
EBL: ECD_00507(rrrD) ECD_00835 ECD_01337(rrrQ) ECD_03189(chiA)
EBE: B21_00513(ybcS) B21_01346(ydfQ) B21_03140(chiA)
ELF: LF82_0302(chiA) LF82_2835(ydfQ) LF82_2836(ydfQ) LF82_397
EFE: EFER_2052(ybcS) EFER_2701(ybcS) EFER_4440(ydfQ)
STY: STY2044 STY3682(nucD) STY4620(nucD2)
STT: t3424(nucD) t4314(nucD)
SPT: SPA2397(gp19) SPA2575(nucD)
SEC: SCH_0986(lycV) SCH_2614(lycV)
SENS: Q786_13170
SEG: SG1208
SEL: SPUL_1731
SET: SEN1145
SENA: AU38_05910
SENO: AU37_05900
SENV: AU39_05900
SENQ: AU40_06635
SENB: BN855_9760 BN855_p30(SBOV47461)
SENE: IA1_05040
SFL: SF0691
SFX: S0733 S0944
SFE: SFxv_0762
SFN: SFy_0942
SFS: SFyv_0980
SDY: SDY_1394
ECLO: ENC_24150
EEC: EcWSU1_02267(arrD) EcWSU1_02428(arrD) EcWSU1_03876(arrD)
ECLZ: LI64_05750
CSK: ES15_0882
CTU: CTU_05120(15) CTU_32330 CTU_34260(arrD)
KVA: Kvar_1790
KOE: A225_5531
CKO: CKO_01876
CAMA: F384_21385
EBF: D782_0219
YPE: YPO2098
YPK: y2216
YPH: YPC_2214
YPN: YPN_1570
YPZ: YPZ3_1736
YPD: YPD4_1848
YPX: YPD8_1703
YPW: CH59_4026(a17)
YPJ: CH55_638(locus17)
YPV: BZ15_1440(a17)
YPL: CH46_3013(a17)
YPQ: DJ40_3626
YPR: BZ20_3309
YFR: AW19_1979
YKR: CH54_3806
SPLY: Q5A_003855(rrrD_1) Q5A_015600(rrrD_2) Q5A_022195(rrrD_3)
SMAF: D781_0833
SERF: L085_00055
PATO: GZ59_43840
ETA: ETA_05770
EPY: EpC_05960
EPR: EPYR_00623(nucD)
PAM: PANA_3151(nucD2) PANA_3414(nucD2)
PAJ: PAJ_0230 PAJ_2653(nucD3)
PVA: Pvag_0285 Pvag_0952(E) Pvag_1702(lycV) Pvag_2694(nucD)
PLU: plu3414
PAY: PAU_03122(gene0068) PAU_03330 PAU_03581(gene0097)
XNE: XNC1_2340
XNM: XNC2_2258
XDO: XDD1_2554
XPO: XPG1_1017
PRG: RB151_029380(rrrD)
ETE: ETEE_2845
HIT: NTHI1880
HIU: HIB_03640
HIK: HifGL_001370(lys)
HSO: HS_1388
MHAT: B824_20680
APL: APL_0505
BTRH: F543_2140
BTRA: F544_21080
XFT: PD_0996(lycV) PD_1113
XAC: XAC1063(p13)
XCI: XCAW_01104(p13)
VAG: N646_1205
VAU: VANGNB10_cI1613c(arrD)
VTA: A0994
PCQ: PcP3B5_03200(rrrD)
PPUT: L483_08410
PMON: X969_11540
PMOT: X970_11195
PFB: VO64_3371
PSEM: TO66_28640
PAR: Psyc_1032
PSYC: DABAL43B_1320(15)
PSYA: AOT82_1071
ABN: AB57_2671
ABAZ: P795_18335
SON: SO_0659
SDN: Sden_3256
PAT: Patl_1492
CBU: CBU_1031
CBD: CBUD_1015
CBG: CbuG_0979
CBC: CbuK_0811
MCA: MCA2680
NHL: Nhal_0995
CSA: Csal_1392
AHA: AHA_2050
AMED: B224_1721
ASR: WL1483_4007(chiA)
CVI: CV_0727 CV_2611(slt)
RPI: Rpic_2043
REH: H16_B1313(h16_B1313)
BPSE: BDL_3279
BPSM: BBQ_2001
BPSU: BBN_2127
BPSD: BBX_1680
BPK: BBK_4319
BPSH: DR55_2311
BPSA: BBU_5665
BUT: X994_231
BTE: BTH_I1920
BCJ: BCAM1918
BCEO: I35_1531
BAM: Bamb_4258
BCED: DM42_3396
BUB: BW23_3321
BLAT: WK25_06190
BPSL: WS57_09190
BMEC: WJ16_07845
BSTG: WT74_29530
PPNO: DA70_08260
BPT: Bpet1003
BAV: BAV1338
TAS: TASI_0464
PUT: PT7_P033
AMIM: MIM_c11010
ODI: ODI_R3024
AAV: Aave_1729
AAA: Acav_3500
DAC: Daci_4670
RTA: Rta_33100
CBAB: SMCB_0671
HAR: HEAR2266
OFO: BRW83_1328(rrrD_1) BRW83_1509(rrrD_2) BRW83_1921(rrrD_3)
THI: THI_1974
RGE: RGE_21600
BBAG: E1O_17010
NEU: NE2534
DSU: Dsui_1505
HPY: HP0339
HPZ: HPKB_0346
HPD: KHP_0331
HPYU: K751_05755
HEB: U063_1309
HEZ: U064_1314
ABU: Abu_1520
ABT: ABED_1418
DDE: Dde_3421
DPI: BN4_11261
PPRF: DPRO_3705
RCO: RC1298
RFE: RF_0924
RRA: RPO_07180
RRC: RPL_07175
RRH: RPM_07150
RRB: RPN_07275
RRN: RPJ_07140
RMI: RMB_06945
RSV: Rsl_1481
RSW: MC3_07205
RAU: MC5_01310
RMO: MCI_03770
RPP: MC1_07165
RRE: MCC_00085
RAM: MCE_00070
AMIH: CO731_04846(rrrD)
SMD: Smed_6523
RLE: RL3920
RPT: Rpal_3077
OCA: OCAR_6584
VGO: GJW-30_1_03773(rrrD)
AZC: AZC_2137
SNO: Snov_2810
MEX: Mext_1416
MET: M446_5979
HDN: Hden_3113
PHL: KKY_731
BVR: BVIR_2344
MSC: BN69_1665
HDI: HDIA_0747(rrrD_1) HDIA_2006(rrrD_2)
CCR: CC_2173
CCS: CCNA_02255(spmX)
CSE: Cseg_2824
PZU: PHZ_c1283
SIT: TM1040_1305(ybcS)
JAN: Jann_2321
KVU: EIO_1251
KVL: KVU_0752
PHP: PhaeoP97_01896(rrrD)
MALG: MALG_02464
HNE: HNE_1271
SSY: SLG_06720
SPMI: K663_11540
AAY: WYH_00121 WYH_01375(rrrD)
ANH: A6F65_01360(rrrD_1) A6F65_02291(rrrD_2)
ADO: A6F68_01470(rrrD)
ACR: Acry_0875
GDJ: Gdia_0567
ASZ: ASN_1442(p13) ASN_1815(p13) ASN_1984(p13)
MAGX: XM1_2594
PPM: PPSC2_03280(murA1)
PPO: PPM_0599(murA1)
LGR: LCGT_0295
LGV: LCGL_0295
SPH: MGAS10270_Spy0722(mur1-1) MGAS10270_Spy0723(mur1-2)
SPJ: MGAS2096_Spy0734(mur1-1) MGAS2096_Spy0735(mur1-2)
LPL: lp_1138(acm1) lp_2645(acm2)
LPJ: JDM1_2121(acm2)
LPT: zj316_2544(acm2)
LPS: LPST_C2173(acm2)
LPZ: Lp16_2086
LSA: LCA_1788
LSI: HN6_00249
LFE: LAF_1820
OOE: OEOE_1199
CML: BN424_1486(mur1) BN424_1487(mur1)
CAC: CA_C0554(lyc)
CBK: CLL_A2241
CCEL: CCDG5_1482
BPRL: CL2_00120
OVA: OBV_20240
BPRS: CK3_26260
SFZ: SFLOR_v1c03000(chiA)
SYN: slr0795
SYY: SYNGTS_2738(slr0795)
SYT: SYNGTI_2737(slr0795)
SYS: SYNPCCN_2736(slr0795)
SYQ: SYNPCCP_2736(slr0795)
SYC: syc0777_c
HHG: XM38_051520(cwlL)
MAR: MAE_60270
CYT: cce_0006
ANA: alr1167
AVA: Ava_4421
CALH: IJ00_01035
TPED: TPE_1728
GBA: J421_2735
TFO: BFO_1263
PRU: PRU_1883
CPI: Cpin_5913
MUC: MuYL_1240
MGOT: MgSA37_01129(rrrD)
CHZ: CHSO_1118
CCH: Cag_0702
PPH: Ppha_0875
IAL: IALB_0081
 » show all
Taxonomy
Reference
1  [PMID:4382801]
  Authors
Blake CC, Johnson LN, Mair GA, North AC, Phillips DC, Sarma VR.
  Title
Crystallographic studies of the activity of hen egg-white lysozyme.
  Journal
Proc R Soc Lond B Biol Sci 167:378-88 (1967)
Reference
2  [PMID:4382800]
  Authors
Blake CC, Mair GA, North AC, Phillips DC, Sarma VR.
  Title
On the conformation of the hen egg-white lysozyme molecule.
  Journal
Proc R Soc Lond B Biol Sci 167:365-77 (1967)
Reference
3
  Authors
Jolles, P.
  Title
Lysozyme.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 4, Academic Press, New York, 1960, p. 431-445.
Other DBs
ExplorEnz - The Enzyme Database: 3.2.1.17
IUBMB Enzyme Nomenclature: 3.2.1.17
ExPASy - ENZYME nomenclature database: 3.2.1.17
BRENDA, the Enzyme Database: 3.2.1.17
CAS: 9001-63-2

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