KEGG   ENZYME: 3.2.1.40Help
Entry
EC 3.2.1.40                 Enzyme                                 

Name
alpha-L-rhamnosidase;
alpha-L-rhamnosidase T;
alpha-L-rhamnosidase N
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
alpha-L-rhamnoside rhamnohydrolase
Reaction(IUBMB)
Hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides
Comment
The enzyme, found in animal tissues, plants, yeasts, fungi and bacteria, utilizes an inverting mechanism of hydrolysis, releasing beta-L-rhamnose. Substrates include naringin, rutin, quercitrin, hesperidin, dioscin, terpenyl glycosides and many other natural glycosides containing terminal alpha-L-rhamnose.
History
EC 3.2.1.40 created 1972
Orthology
K05989  alpha-L-rhamnosidase
Genes
CLU: CLUG_02923
CLUS: A9F13_18g00374
MGR: MGG_02192
TMN: UCRPA7_8651
SSCK: SPSK_01446 SPSK_03958
FGR: FGSG_07974 FGSG_09073 FGSG_10686
FPU: FPSE_05713 FPSE_06106 FPSE_07358
FVR: FVEG_03189 FVEG_03332 FVEG_07769 FVEG_11748 FVEG_12337
FOX: FOXG_04665 FOXG_04792 FOXG_04947 FOXG_10845 FOXG_11916 FOXG_13192 FOXG_15252 FOXG_15491 FOXG_15493 FOXG_17228
NHE: NECHADRAFT_45470 NECHADRAFT_71326 NECHADRAFT_84396 NECHADRAFT_85306 NECHADRAFT_85493 NECHADRAFT_87874
MBE: MBM_00922
ANG: ANI_1_1354184(An04g09070)
CNE: CNG00310
CNB: CNBG4460
KPU: KP1_2883
KPP: A79E_2408
KPJ: N559_2468
RAA: Q7S_10540
DDQ: DDI_3072
CARE: LT85_2532
ARA: Arad_4468
RLE: pRL100260
RLG: Rleg_6531
CCR: CC_0978
CSE: Cseg_1766
SSAN: NX02_08680
SPKC: KC8_02390
BCZ: BCE33L2019(ramA)
BCQ: BCQ_2173(ramA)
BCX: BCA_2320
BAL: BACI_c21920(ramA)
BNC: BCN_2162
BCF: bcf_11215
BCER: BCK_23645
BTK: BT9727_2019(ramA)
BTL: BALH_1999
BGY: BGLY_3078
PPM: PPSC2_17850(ramA)
PPO: PPM_3594(ramA)
PPOL: X809_33935
PPOY: RE92_19345
PSWU: SY83_08860
SCF: Spaf_1778
LPL: lp_3471(ram1) lp_3473(ram2)
LAC: LBA1473
LAD: LA14_1467
LAF: SD55_1450
LRH: LGG_02433
LRG: LRHM_2345
LRA: LRHK_2446
ECAS: ECBG_00295
MPS: MPTP_1902
MPX: MPD5_1695
CSR: Cspa_c29060(ramA1) Cspa_c29140 Cspa_c32220(ramA2)
CSS: Cst_c10630(ramA)
CSD: Clst_1016
FPA: FPR_25430
BPB: bpr_I1686(rha78A)
ABRA: BN85301020
NFA: NFA_34020
GOR: KTR9_2812
SCO: SCO0369(SCF41.28c) SCO0488(SCF34.07)
SGB: WQO_32070
SFA: Sfla_5912
STRP: F750_0658
SFI: SFUL_6813
SPRI: SPRI_6486
SLE: sle_61760(sle_61760)
CMI: CMM_0105(ramA)
BCV: Bcav_3620
CFI: Celf_2980
MPH: MLP_09660(ramA) MLP_52110(ramA)
AMI: Amir_2047
ASE: ACPL_2732
ACTS: ACWT_2814
CAI: Caci_3741
SNA: Snas_2877
BDE: BDP_0161
BDN: BBDE_0149
BBRC: B7019_1625
BSCA: BBSC_2412
CWO: Cwoe_0243
RCA: Rcas_1874
CAU: Caur_0361
CAG: Cagg_0532
CAP: CLDAP_39130(ramA)
DGE: Dgeo_2783
TTR: Tter_2708
OTE: Oter_3063
RBA: RB700(ramA)
TTF: THTE_2101
ABAS: ACPOL_1527
SUS: Acid_5559
GBA: J421_5647
BVU: BVU_2645
TFO: BFO_0711
RMR: Rmar_0689
LBY: Lbys_1755
FAE: FAES_1723(ramA) FAES_4682
FJO: Fjoh_4080
ZPR: ZPR_1542
ZGA: ZOBELLIA_3522(rhaA)
MARF: CJ739_946
TPT: Tpet_1682
HUT: Huta_0156
HTU: Htur_3899
SID: M164_2337
SII: LD85_2626
SIH: SiH_2270
SIR: SiRe_2217
SIC: SiL_2179
CMA: Cmaq_0172
 » show all
Taxonomy
Reference
1  [PMID:5855461]
  Authors
Rosenfeld EL, Wiederschein GY.
  Title
The metabolism of L-rhamnose in animal tissues.
  Journal
Bull Soc Chim Biol (Paris) 47:1433-40 (1965)
Reference
2  [PMID:4632197]
  Authors
Kurosawa Y, Ikeda K, Egami F
  Title
-L-rhamnosidases of the liver of Turbo cornutus and Aspergillus niger.
  Journal
J Biochem 73:31-7 (1973)
Reference
3  [PMID:10632887]
  Authors
Zverlov VV, Hertel C, Bronnenmeier K, Hroch A, Kellermann J, Schwarz WH
  Title
The thermostable alpha-L-rhamnosidase RamA of Clostridium stercorarium: biochemical characterization and primary structure of a bacterial alpha-L-rhamnoside hydrolase, a new type of inverting glycoside hydrolase.
  Journal
Mol Microbiol 35:173-9 (2000)
DOI:10.1046/j.1365-2958.2000.01691.x
  Sequence
Reference
4  [PMID:11129592]
  Authors
Yanai T, Sato M
  Title
Purification and characterization of an alpha-L-rhamnosidase from Pichia angusta  X349.
  Journal
Biosci Biotechnol Biochem 64:2179-85 (2000)
DOI:10.1271/bbb.64.2179
Reference
5  [PMID:17936784]
  Authors
Cui Z, Maruyama Y, Mikami B, Hashimoto W, Murata K
  Title
Crystal structure of glycoside hydrolase family 78 alpha-L-Rhamnosidase from Bacillus sp. GL1.
  Journal
J Mol Biol 374:384-98 (2007)
DOI:10.1016/j.jmb.2007.09.003
Reference
6  [PMID:24815685]
  Authors
Rabausch U, Ilmberger N, Streit WR
  Title
The metagenome-derived enzyme RhaB opens a new subclass of bacterial B type alpha-L-rhamnosidases.
  Journal
J Biotechnol 191:38-45 (2014)
DOI:10.1016/j.jbiotec.2014.04.024
Other DBs
ExplorEnz - The Enzyme Database: 3.2.1.40
IUBMB Enzyme Nomenclature: 3.2.1.40
ExPASy - ENZYME nomenclature database: 3.2.1.40
BRENDA, the Enzyme Database: 3.2.1.40
CAS: 37288-35-0

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