KEGG   ENZYME: 3.2.1.96Help
Entry
EC 3.2.1.96                 Enzyme                                 

Name
mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase;
N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase;
endo-beta-N-acetylglucosaminidase;
mannosyl-glycoprotein endo-beta-N-acetylglucosamidase;
di-N-acetylchitobiosyl beta-N-acetylglucosaminidase;
endo-beta-acetylglucosaminidase;
endo-beta-(1->4)-N-acetylglucosaminidase;
mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase;
endoglycosidase S;
endo-N-acetyl-beta-D-glucosaminidase;
endo-N-acetyl-beta-glucosaminidase;
endo-beta-N-acetylglucosaminidase D;
endo-beta-N-acetylglucosaminidase F;
endo-beta-N-acetylglucosaminidase H;
endo-beta-N-acetylglucosaminidase L;
glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase;
endoglycosidase H
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase
Reaction(IUBMB)
Endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn- structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact
Comment
A group of related enzymes.
History
EC 3.2.1.96 created 1978
Pathway
ec00511  Other glycan degradation
Orthology
K01227  mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
K13714  bifunctional autolysin
Genes
HSA: 64772(ENGASE)
PTR: 741918(ENGASE)
PPS: 100973178(ENGASE)
GGO: 101150692(ENGASE)
PON: 100454020(ENGASE)
NLE: 100602480(ENGASE)
MCC: 716600(ENGASE)
MCF: 102133743(ENGASE)
CSAB: 103243673(ENGASE)
RRO: 104677034(ENGASE)
RBB: 108522612 108534163(ENGASE)
CJC: 100408278(ENGASE)
SBQ: 101028520(ENGASE)
MMU: 217364(Engase)
RNO: 303702(Engase)
CGE: 100754028(Engase)
NGI: 103747297(Engase)
HGL: 101711000(Engase)
CCAN: 109682706(Engase)
OCU: 100352061(ENGASE)
TUP: 102480939(ENGASE)
CFA: 483347(ENGASE)
AML: 100480585(ENGASE)
UMR: 103665970(ENGASE)
ORO: 101368695(ENGASE)
FCA: 101084586(ENGASE)
PTG: 102954302(ENGASE)
AJU: 106981886(ENGASE)
BTA: 100847654(ENGASE)
BOM: 102273299(ENGASE)
BIU: 109574193(ENGASE)
PHD: 102332440(ENGASE)
CHX: 102187164(ENGASE)
OAS: 101112239(ENGASE)
SSC: 100620304(ENGASE)
CFR: 102507867 102521905(ENGASE)
CDK: 105105799(ENGASE)
BACU: 103014781(ENGASE)
LVE: 103079880(ENGASE)
OOR: 101289334(ENGASE)
ECB: 100057280(ENGASE)
EPZ: 103551450(ENGASE)
EAI: 106845428(ENGASE)
MYB: 102251109(ENGASE)
MYD: 102768955(ENGASE)
HAI: 109383669(ENGASE)
RSS: 109449404(ENGASE)
PALE: 102895333(ENGASE)
LAV: 100661749(ENGASE)
TMU: 101346385
MDO: 100030963(ENGASE)
SHR: 100933583(ENGASE)
OAA: 103167700(ENGASE)
GGA: 430102(ENGASE)
MGP: 100548667(ENGASE)
CJO: 107322202(ENGASE)
APLA: 101797822(ENGASE)
ACYG: 106046786(ENGASE)
TGU: 100218273(ENGASE)
GFR: 102035651(ENGASE)
FAB: 101806132(ENGASE)
PHI: 102108468(ENGASE)
PMAJ: 107212278(ENGASE)
CCAE: 111946025(ENGASE)
CCW: 104698235(ENGASE)
FPG: 106112875(ENGASE)
FCH: 106630976(ENGASE)
CLV: 102091638(ENGASE)
ASN: 102387987(ENGASE)
AMJ: 102558652(ENGASE)
CMY: 102948233(ENGASE)
CPIC: 101932012(ENGASE)
ACS: 100563201(engase)
PVT: 110090256(ENGASE)
PBI: 103052676(ENGASE)
GJA: 107115310(ENGASE)
XLA: 108701020(engase.L)
XTR: 100496567(engase)
NPR: 108796392(ENGASE)
DRE: 561239(engase)
SANH: 107654484
IPU: 108255229(engase)
AMEX: 103023008(engase)
TRU: 101063945(engase)
LCO: 104935250(engase)
NCC: 104942170(engase) 104956773
MZE: 101481803(engase)
OLA: 101173709(engase)
XMA: 102222558(engase)
PRET: 103468191(engase)
NFU: 107391604(engase)
KMR: 108249446(engase)
CSEM: 103393592(engase)
LCF: 108894788 108898518(engase)
SDU: 111217800(engase)
HCQ: 109532533(engase)
BPEC: 110162491(engase)
MALB: 109964786(engase)
ELS: 105031324(engase)
SFM: 108936748(engase)
LCM: 102356083(ENGASE)
CMK: 103175711 103175727(engase)
CIN: 100187187
SPU: 589610
APLC: 110978556
DME: Dmel_CG5613(CG5613)
DER: 6550068
DSI: Dsimw501_GD15670(Dsim_GD15670)
DWI: 6641412
AAG: 5576074
AME: 725194
BIM: 100748091
BTER: 100647282
AEC: 105145018
ACEP: 105619374
PBAR: 105430240
HST: 105189893
DQU: 106742020
CFO: 105250964
LHU: 105669133
PGC: 109858342
PCF: 106791640
NVI: 100123355
TCA: 658146
DPA: 109544621
NVL: 108569756
BMOR: 101738110
PMAC: 106721420
PRAP: 111002373
HAW: 110381450
PXY: 105383219
API: 100168559
DNX: 107167214
ZNE: 110835745
FCD: 110848180
TUT: 107361598
CEL: CELE_F01F1.10(eng-1)
CBR: CBG09066(Cbr-eng-1)
BMY: Bm1_17595
MYI: 110443190
OBI: 106879857
LAK: 106168750
SHX: MS3_02680
EGL: EGR_02247
EPA: 110253881
ADF: 107347524
HMG: 100206857
AQU: 100640537
ATH: AT3G11040(ENGase85B) AT5G05460(ENGase85A)
THJ: 104816686
CPAP: 110819233
TCC: 18585799
EGR: 104421044
CAM: 101508143
LJA: Lj2g3v2827790.1(Lj2g3v2827790.1) Lj6g3v0466940.1(Lj6g3v0466940.1) Lj6g3v0467170.1(Lj6g3v0467170.1)
LANG: 109328030
FVE: 101305521
PPER: 18785095
PMUM: 103332830
PAVI: 110761807
ZJU: 107413911
MCHA: 111015965
JRE: 109004747
VVI: 100265715
SLY: 101261626(Endo-LE)
SOT: 102581655
CANN: 107873290
NSY: 104216517
NTO: 104099429
INI: 109186863
OEU: 111397532
HAN: 110920782
LSV: 111879872
CCAV: 112528917
DCR: 108214132
BVG: 104905964
SOE: 110795139
NNU: 104597282
OSA: 4338487
DOSA: Os05t0346500-01(Os05g0346500)
OBR: 102704525
BDI: 100830365
ATS: 109741928(LOC109741928)
SBI: 8083737
ZMA: 103635582
SITA: 101768644
PDA: 103717481
EGU: 105045078
DCT: 110094090
PEQ: 110028321
ATR: 18437159
PPP: 112281157
MNG: MNEG_1484
PTE: PTT_19838
ABP: AGABI1DRAFT109029(AGABI1DRAFT_109029)
ABV: AGABI2DRAFT181728(AGABI2DRAFT_181728)
MGL: MGL_3822
DFA: DFA_07625
SPAR: SPRG_14941
TCR: 511577.50
BSU: BSU35780(lytD)
BSR: I33_3707(lytD)
BSL: A7A1_1139
BSH: BSU6051_35780(lytD)
BSUT: BSUB_03811(lytD)
BSUL: BSUA_03811(lytD)
BSUS: Q433_19615
BSS: BSUW23_17585(lytD)
BST: GYO_3937(lytD)
BSO: BSNT_10221(lytD)
BSQ: B657_35780(lytD)
BSX: C663_3472(lytD)
BLI: BL02465(lytD)
BLD: BLi03821(lytD)
BLH: BaLi_c38330(lytD)
BAY: RBAM_032900(lytD)
BAQ: BACAU_3320(lytD)
BYA: BANAU_3479(lytD)
BAMP: B938_16895
BAML: BAM5036_3214(lytD)
BAMA: RBAU_3430(lytD)
BAMN: BASU_3208(lytD)
BAMB: BAPNAU_3487(lytD)
BAMT: AJ82_18575
BAMY: V529_35580(lytD)
BMP: NG74_03466(lytD)
BAO: BAMF_3416(lytD)
BAZ: BAMTA208_18100(lytD)
BQL: LL3_03711(lytD)
BXH: BAXH7_03700(lytD)
BQY: MUS_3918(lytD)
BAMI: KSO_002620
BAMC: U471_34170
BAMF: U722_17640
BCL: ABC3097
BPU: BPUM_3233
BPUM: BW16_17255
BPUS: UP12_16745
BAG: Bcoa_0850
BCOA: BF29_2876(lytD)
BJS: MY9_3634
BACW: QR42_16250
BACP: SB24_12245
BACB: OY17_00130
BACY: QF06_16310
BACL: BS34A_38910(lytD)
BALM: BsLM_3594
BGY: BGLY_4218
BKW: BkAM31D_21410(lytD)
OIH: OB2911
GEA: GARCT_03212(lytD)
ANM: GFC28_2982(lytD)
ANL: GFC29_2453(lytD)
AXL: AXY_20270
VPN: A21D_00873(lytD)
SAU: SA0905(atl)
SAV: SAV1052(truncated-atl)
SAW: SAHV_1045
SAM: MW0936(atl)
SAS: SAS0988
SAR: SAR1026(atl)
SAC: SACOL1062(atl)
SAA: SAUSA300_0955(atl)
SAE: NWMN_0922(atl)
SAD: SAAV_1017(atl)
SUJ: SAA6159_00909(atl)
SUK: SAA6008_01007(atl)
SUC: ECTR2_908
SUZ: MS7_1010(atl)
SUX: SAEMRSA15_08840(atl)
SUW: SATW20_10490(atl)
SUG: SAPIG1050
SUF: SARLGA251_09670(atl)
SAUA: SAAG_02164
SAUE: RSAU_000940(atl)
SAUS: SA40_0923(atl)
SAUU: SA957_0938(atl)
SAUG: SA268_0941(atl)
SAUZ: SAZ172_0993(atl)
SAUT: SAI1T1_2007440(atl)
SAUJ: SAI2T2_1007460(atl)
SAUK: SAI3T3_1007450(atl)
SAUQ: SAI4T8_1007440(atl)
SAUV: SAI7S6_1007450(atl)
SAUW: SAI5S5_1007410(atl)
SAUX: SAI6T6_1007420(atl)
SAUY: SAI8T7_1007450(atl)
SAUF: X998_1052
SAB: SAB0919c(atl)
SUY: SA2981_1007(atl)
SAUB: C248_1078(atl)
SAUM: BN843_9590
SAUC: CA347_969(atl)
SAUR: SABB_01019(atl)
SAUI: AZ30_05025
SAUD: CH52_00620
SAMS: NI36_05040
SEP: SE0750
SER: SERP0636(atlE)
SEPP: SEB_00726
SEPS: DP17_2083(atl)
SHA: SH1911(atl)
SHH: ShL2_01775(atl)
SSP: SSP1741
SCA: SCA_0659(bph)
SLN: SLUG_18190(atl)
SDT: SPSE_1762(spsC)
SPAS: STP1_2110
SCAP: AYP1020_0374(atl_3)
SSCH: LH95_08525
SSCZ: RN70_09005
SAGQ: EP23_01315
MCAK: MCCS_08730(atl_1)
LIV: LIV_1022
ESI: Exig_2547
EAN: Eab7_2390
GMO: NCTC11323_00094(lytB_2) NCTC11323_00096(lytB_3)
PPOY: RE92_13305
JEO: JMA_43170
LLK: LLKF_1605(ypcCD)
LLM: llmg_1087(acmC) llmg_2165(acmB)
SPZ: M5005_Spy1540(endoS)
SPYM: M1GAS476_1618(endoS)
SPYA: A20_1589c(endoS)
SPH: MGAS10270_Spy1607(endoS)
SPI: MGAS10750_Spy1599(endoS)
SPJ: MGAS2096_Spy1565(endoS)
SPK: MGAS9429_Spy1544(endoS)
SPF: SpyM50309
SPB: M28_Spy1527(endoS)
STG: MGAS15252_1383(endoS)
STX: MGAS1882_1444(endoS)
STZ: SPYALAB49_001531(endoS)
SPYH: L897_07405
SPN: SP_0965(lytB)
SPD: SPD_0853(lytB) SPD_1403(lytC)
SPR: spr0867(lytB)
SPW: SPCG_0941(lytB)
SJJ: SPJ_0906
SNV: SPNINV200_08860(lytB)
SPX: SPG_0889(lytB)
SNT: SPT_1238
SND: MYY_1239
SPNN: T308_05795
SNE: SPN23F08900(lytB)
SPV: SPH_1067
SPP: SPP_0971
SNI: INV104_08260(lytB)
SNP: SPAP_0997
SNX: SPNOXC08670(lytB)
SNU: SPNA45_01263(lytB)
SPNE: SPN034156_19090(lytB)
SPNU: SPN034183_08650(lytB)
SPNM: SPN994038_08540(lytB)
SPNO: SPN994039_08550(lytB)
SEZ: Sez_0364(endOF2)
SEQ: SZO_16140(ndoS)
SEQU: Q426_07470
SEU: SEQ_0432
SMB: smi_0966(lytB)
SOR: SOR_1204(lytB)
SIK: K710_1887
STRN: SNAG_1216(lytB_4)
LPL: lp_0182
LBR: LVIS_1883
LRT: LRI_0628
LBH: Lbuc_0198
OOE: OEOE_0144
HSC: HVS_03505(atl1) HVS_03550(atl2)
COO: CCU_17970
BPRL: CL2_28250
BPRS: CK3_19040
PAC: PPA0990
SRO: Sros_4999
CHU: CHU_1472(flgJ)
 » show all
Taxonomy
Reference
1
  Authors
Chien, S., Weinburg, R., Li, S. and Li, Y.
  Title
Endo-beta-N-acetylglucosaminidase from fig latex.
  Journal
Biochem Biophys Res Commun 76:317-323 (1977)
Reference
2  [PMID:4152561]
  Authors
Koide N, Muramatsu T.
  Title
Endo-beta-N-acetylglucosaminidase acting on carbohydrate moieties of glycoproteins. Purification and properties of the enzyme from Diplococcus pneumoniae.
  Journal
J Biol Chem 249:4897-904 (1974)
Reference
3  [PMID:486141]
  Authors
Pierce RJ, Spik G, Montreuil J.
  Title
Cytosolic location of an endo-N-acetyl-beta-D-glucosaminidase activity in rat liver and kidney.
  Journal
Biochem J 180:673-76 (1979)
Reference
4  [PMID:7378051]
  Authors
Pierce RJ, Spik G, Montreuil J.
  Title
Demonstration and cytosolic location of an endo-N-acetyl-beta-D-glucosaminidase activity towards an asialo-N-acetyl-lactosaminic-type substrate in rat liver.
  Journal
Biochem J 185:261-4 (1980)
Reference
5  [PMID:389]
  Authors
Tai T, Yamashita K, Ogata-Arakawa M, Koide N, Muramatsu T, Iwashita S, Inoue Y, Kobata A.
  Title
Structural studies of two ovalbumin glycopeptides in relation to the endo-beta-N-acetylglucosaminidase specificity.
  Journal
J Biol Chem 250:8569-75 (1975)
Reference
6  [PMID:4204553]
  Authors
Tarentino AL, Plummer TH Jr, Maley F.
  Title
The release of intact oligosaccharides from specific glycoproteins by endo-beta-N-acetylglucosaminidase H.
  Journal
J Biol Chem 249:818-24 (1974)
Other DBs
ExplorEnz - The Enzyme Database: 3.2.1.96
IUBMB Enzyme Nomenclature: 3.2.1.96
ExPASy - ENZYME nomenclature database: 3.2.1.96
BRENDA, the Enzyme Database: 3.2.1.96
CAS: 37278-88-9

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