| Entry |
|
|---|
| Name |
glutamyl aminopeptidase;
aminopeptidase A;
aspartate aminopeptidase;
angiotensinase A;
glutamyl peptidase;
Ca2+-activated glutamate aminopeptidase;
membrane aminopeptidase II;
antigen BP-1/6C3 of mouse B lymphocytes;
L-aspartate aminopeptidase;
angiotensinase A2
|
|---|
| Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Aminopeptidases
 |
|---|
| Reaction(IUBMB) |
Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide
|
|---|
| Comment |
Ca2+-activated and generally membrane-bound. A zinc-metallopeptidase in family M1 (membrane alanyl aminopeptidase family)
|
|---|
| History |
EC 3.4.11.7 created 1972
|
|---|
| Orthology |
| K01261 | glutamyl aminopeptidase |
| K11141 | glutamyl aminopeptidase |
|
|---|
| Genes |
» show all
 |
|---|
| Reference |
|
|---|
| Authors |
GLENNER GG, McMILLAN PJ, FOLK JE. |
|---|
| Title |
A mammalian peptidase specific for the hydrolysis of N-terminal alpha-L-glutamyl and aspartyl residues. |
|---|
| Journal |
Nature 194:867 (1962) |
|---|
| Reference |
|
|---|
| Authors |
Chulkova TM, Orekhovich VN. |
|---|
| Title |
[Molecular structure of aminopeptidase A from bovine kidney] |
|---|
| Journal |
Biokhimiia 44:1539-41 (1979) |
|---|
| Reference |
|
|---|
| Authors |
Danielsen EM, Noren O, Sjostrom H, Ingram J, Kenny AJ. |
|---|
| Title |
Proteins of the kidney microvillar membrane. Aspartate aminopeptidase: purification by immunoadsorbent chromatography and properties of the detergent- and proteinase-solubilized forms. |
|---|
| Journal |
Biochem J 189:591-603 (1980) |
|---|
| Reference |
|
|---|
| Authors |
Tobe H, Kojima F, Aoyagi T, Umezawa H. |
|---|
| Title |
Purification by affinity chromatography using amastatin and properties of aminopeptidase A from pig kidney. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Wu Q, Lahti JM, Air GM, Burrows PD, Cooper MD. |
|---|
| Title |
Molecular cloning of the murine BP-1/6C3 antigen: a member of the zinc-dependent metallopeptidase family. |
|---|
| Journal |
|
|---|
| Sequence |
|
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.4.11.7 |
| ExPASy - ENZYME nomenclature database: | 3.4.11.7 |
|
|---|
