Entry |
|
Name |
tripeptidyl-peptidase II;
tripeptidyl aminopeptidase;
tripeptidyl peptidase;
tripeptidyl aminopeptidase II;
tripeptidyl peptidase II;
TPP
|
Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Dipeptidyl-peptidases and tripeptidyl-peptidases
 |
Reaction(IUBMB) |
Release of an N-terminal tripeptide from a polypeptide
|
Comment |
A cytosolic enzyme in peptidase family S8 (subtilisin family). Active at neutral pH. Inhibited by diisopropyl fluorophosphate. Formerly included in EC 3.4.14.8
|
History |
EC 3.4.14.10 created 1992 (part of EC 3.4.14.8 created 1989, incorporated 1992)
|
Orthology |
K01280 | tripeptidyl-peptidase II |
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Genes |
» show all
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Reference |
|
Authors |
Balow RM, Ragnarsson U, Zetterqvist O. |
Title |
Tripeptidyl aminopeptidase in the extralysosomal fraction of rat liver. |
Journal |
J Biol Chem 258:11622-8 (1983) |
Reference |
|
Authors |
Balow RM, Tomkinson B, Ragnarsson U, Zetterqvist O. |
Title |
Purification, substrate specificity, and classification of tripeptidyl peptidase II. |
Journal |
J Biol Chem 261:2409-17 (1986) |
Reference |
|
Authors |
Tomkinson B, Zetterqvist O. |
Title |
Immunological cross-reactivity between human tripeptidyl peptidase II and fibronectin. |
Journal |
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Sequence |
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Other DBs |
ExPASy - ENZYME nomenclature database: | 3.4.14.10 |
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