KEGG   ENZYME: 3.4.14.2Help
Entry
EC 3.4.14.2                 Enzyme                                 

Name
dipeptidyl-peptidase II;
dipeptidyl aminopeptidase II;
dipeptidyl arylamidase II;
carboxytripeptidase;
dipeptidyl peptidase II;
dipeptidyl arylamidase II;
DAP II;
dipeptidyl(amino)peptidase II;
dipeptidylarylamidase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Dipeptidyl-peptidases and tripeptidyl-peptidases
BRITE hierarchy
Reaction(IUBMB)
Release of an N-terminal dipeptide, Xaa-Yaa!, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides
Comment
A lysosomal serine-type peptidase in family S28 (Pro-X carboxypeptidase family); maximally active at acidic pH
History
EC 3.4.14.2 created 1978
Orthology
K01276  dipeptidyl-peptidase II
Genes
HSA: 29952(DPP7)
PTR: 473101(DPP7)
PPS: 100976342(DPP7)
GGO: 101136044(DPP7)
PON: 100174214(DPP7)
NLE: 100595263(DPP7)
MCC: 721595(DPP7)
MCF: 101867244(DPP7)
CSAB: 103239581(DPP7)
RRO: 104669635(DPP7)
RBB: 108542890(DPP7)
CJC: 100413498(DPP7)
SBQ: 101032597(DPP7)
MMU: 83768(Dpp7)
RNO: 83799(Dpp7)
CGE: 100756223(Dpp7)
NGI: 103741174(Dpp7)
HGL: 101724543(Dpp7)
CCAN: 109697988(Dpp7)
TUP: 102470111(DPP7)
CFA: 607003(DPP7)
AML: 100467965(DPP7)
UMR: 103675309(DPP7)
ORO: 101379800(DPP7)
FCA: 101095966(DPP7)
PTG: 102948665(DPP7)
AJU: 106989098(DPP7)
BTA: 100125760(DPP7)
BOM: 102277526(DPP7)
PHD: 102323507(DPP7)
CHX: 102182320(DPP7)
SSC: 100626630(DPP7)
CFR: 102514636(DPP7)
CDK: 105106184(DPP7)
BACU: 103002313(DPP7)
LVE: 103077546(DPP7)
OOR: 101274898(DPP7)
ECB: 100059924(DPP7)
EPZ: 103568010(DPP7)
EAI: 106845520(DPP7)
MYD: 102751478(DPP7)
HAI: 109381795(DPP7)
RSS: 109460972(DPP7)
PALE: 102890830(DPP7)
LAV: 100664342(DPP7)
TMU: 101354737
MDO: 100022760(DPP7)
SHR: 100918941(DPP7)
GGA: 417297(DPP7)
MGP: 100543847(DPP7)
CJO: 107321630(DPP7)
APLA: 101791397(DPP7)
ACYG: 106037124(DPP7)
TGU: 100226334(DPP7)
GFR: 102031390(DPP7)
FAB: 101815871(DPP7)
CCW: 104688194(DPP7)
FPG: 101914257(DPP7)
FCH: 102051827(DPP7)
CLV: 102083967(DPP7)
EGZ: 104123973(DPP7)
AAM: 106494235(DPP7)
ASN: 102372722(DPP7)
AMJ: 102571172(DPP7)
PSS: 102447055 102456165(DPP7)
CMY: 102944633(DPP7)
CPIC: 101946841(DPP7)
ACS: 100562590(dpp7)
PVT: 110078851(DPP7)
PBI: 103050059(DPP7)
GJA: 107123276(DPP7)
DRE: 503737(dpp7)
SRX: 107709692
SANH: 107681243(dpp7) 107690688
SGH: 107560239
IPU: 108255762(dpp7)
AMEX: 103027831(dpp7)
TRU: 101061692(dpp7)
LCO: 104925283(dpp7)
NCC: 104966816(dpp7)
MZE: 101469493(dpp7)
OLA: 101156583(dpp7)
XMA: 102233162(dpp7)
PRET: 103469621(dpp7)
KMR: 108245624(dpp7)
CSEM: 103397365(dpp7)
LCF: 108878395(dpp7)
SDU: 111226926(dpp7)
HCQ: 109510557(dpp7)
BPEC: 110154650(dpp7)
MALB: 109959747(dpp7)
SASA: 106585425(dpp7)
OTW: 112232798(dpp7)
ELS: 105014134(dpp7)
SFM: 108938628(dpp7)
LCM: 102363610(DPP7)
CMK: 103180401(dpp7)
CIN: 100179268
SPU: 592836
CRG: 105320441
MYI: 110466518
OBI: 106877801
LAK: 106179479
SHX: MS3_05939
EGL: EGR_02544
EPA: 110231171
HMG: 100200663
SMIN: v1.2.010901.t2(symbB.v1.2.010901.t2) v1.2.018349.t1(symbB.v1.2.018349.t1) v1.2.019631.t1(symbB.v1.2.019631.t1)
 » show all
Taxonomy
Reference
1  [PMID:4969969]
  Authors
McDonald JK, Leibach FH, Grindeland RE, Ellis S.
  Title
Purification of  dipeptidyl aminopeptidase II (dipeptidyl arylamidase II) of the anterior pituitary gland. Peptidase and dipeptide esterase activities.
  Journal
J Biol Chem 243:4143-50 (1968)
Reference
2
  Authors
McDonald, J.K. and Schwabe, C.
  Title
Intracellular exopeptidases.
  Journal
In: Barrett, A.J. (Ed.), Proteinases in Mammalian Cells and Tissues, North-Holland Publishing Co., Amsterdam, 1977, p. 311-391.
Other DBs
ExplorEnz - The Enzyme Database: 3.4.14.2
IUBMB Enzyme Nomenclature: 3.4.14.2
ExPASy - ENZYME nomenclature database: 3.4.14.2
BRENDA, the Enzyme Database: 3.4.14.2
CAS: 76199-23-0

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