KEGG   ENZYME: 3.4.17.15Help
Entry
EC 3.4.17.15                Enzyme                                 

Name
carboxypeptidase A2;
CPA2
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metallocarboxypeptidases
BRITE hierarchy
Reaction(IUBMB)
Similar to that of carboxypeptidase A (EC 3.4.17.1), but with a preference for bulkier C-terminal residues
Comment
Isolated from rat pancreas but not present in cattle pancreas. In peptidase family M14 (carboxypeptidase A family).
History
EC 3.4.17.15 created 1992
Orthology
K01298  carboxypeptidase A2
Genes
HSA: 1358(CPA2)
PTR: 742070(CPA2)
PPS: 100983954(CPA2)
GGO: 101152905(CPA2)
PON: 100458672(CPA2)
NLE: 100603285(CPA2)
MCC: 706684(CPA2)
MCF: 102130332(CPA2)
CSAB: 103226899(CPA2)
RRO: 104674462(CPA2)
RBB: 108531579(CPA2)
CJC: 100394759(CPA2)
SBQ: 101041379(CPA2)
MMU: 232680(Cpa2)
RNO: 296959(Cpa2)
CGE: 100756609(Cpa2)
NGI: 103744539(Cpa2)
HGL: 101700104(Cpa2)
CCAN: 109699195(Cpa2)
OCU: 100349998(CPA2)
TUP: 102489569(CPA2)
CFA: 475193(CPA2)
AML: 100478542(CPA2)
UMR: 103676659(CPA2)
ORO: 101377290(CPA2)
FCA: 101088825(CPA2)
PTG: 102964595(CPA2)
AJU: 106973910(CPA2)
SSC: 100516306(CPA2)
CFR: 102506813(CPA2)
CDK: 105085436(CPA2)
BACU: 103017822(CPA2)
LVE: 103072366(CPA2)
OOR: 101271769(CPA2)
ECB: 100071976(CPA2)
EPZ: 103546308(CPA2)
EAI: 106839552(CPA2)
MYB: 102252999(CPA2)
MYD: 102774890(CPA2)
HAI: 109384648(CPA2)
RSS: 109457289(CPA2)
PALE: 102890562(CPA2)
LAV: 100670502(CPA2)
TMU: 101350660
SHR: 100931516 105750808
OAA: 100075672(CPA2)
GGA: 416682(CPA2)
MGP: 100544216(CPA2)
CJO: 107311052
APLA: 101805104
ACYG: 106038763
TGU: 100223967(CPA2)
GFR: 102043912(CPA2)
FAB: 101813935(CPA2)
PHI: 102108782(CPA2)
PMAJ: 107204465
CCAE: 111923181
CCW: 104695959
FPG: 101922417(CPA2)
FCH: 102060013(CPA2)
CLV: 102098475
EGZ: 104123449(CPA2)
AAM: 106489370
ASN: 102378634
AMJ: 102563587
PSS: 102460988
CMY: 102943016(CPA2)
CPIC: 101942769(CPA2)
ACS: 100564619(cpa2)
PVT: 110089541(CPA2)
PBI: 103049745
GJA: 107126156
NPR: 108795098
DRE: 431764(cpa4)
SRX: 107707477 107732822 107732823
SANH: 107686633 107686634 107700998
SGH: 107573279 107573291 107575283 107580111
CCAR: 109064543 109075613 109106962 109107513
IPU: 108269193
AMEX: 103026101
LCO: 104925102
MZE: 101471320
OLA: 101159188
XMA: 102220042
PRET: 103465733
NFU: 107373388
KMR: 108244221
LCF: 108880871
SDU: 111229836
MALB: 109956419
SASA: 100195850(cbpa2)
OTW: 112218875
ELS: 105026416
LCM: 102353863
BFO: BRAFLDRAFT_118166 BRAFLDRAFT_166229 BRAFLDRAFT_212027 BRAFLDRAFT_240860
CIN: 100183283
APLC: 110979600 110979627 110984857
SKO: 100367846 100373689
FCD: 110854910 110859269
DPX: DAPPUDRAFT_194294 DAPPUDRAFT_224487 DAPPUDRAFT_303899 DAPPUDRAFT_59834
ISC: IscW_ISCW007749 IscW_ISCW015949 IscW_ISCW023731
TUT: 107359279
HRO: HELRODRAFT_107037 HELRODRAFT_107038 HELRODRAFT_107039 HELRODRAFT_185228 HELRODRAFT_188933
CRG: 105320968 105326769 105345633
MYI: 110462445
OBI: 106873122 106876015 106882490
LAK: 106166930
SMM: Smp_088270
EGL: EGR_10235 EGR_11299
EPA: 110250771 110251757 110254954
ADF: 107350259
SPAR: SPRG_16360
 » show all
Taxonomy
Reference
1  [PMID:3182871]
  Authors
Gardell SJ, Craik CS, Clauser E, Goldsmith EJ, Stewart CB, Graf M, Rutter WJ
  Title
A novel rat carboxypeptidase, CPA2: characterization, molecular cloning, and evolutionary implications on substrate specificity in the carboxypeptidase gene family.
  Journal
J Biol Chem 263:17828-36 (1988)
  Sequence
[rno:296959]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.17.15
IUBMB Enzyme Nomenclature: 3.4.17.15
ExPASy - ENZYME nomenclature database: 3.4.17.15
BRENDA, the Enzyme Database: 3.4.17.15
CAS: 181186-98-1

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Gene (2416)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (145)   
   KEGG MGENES (51)   
   RefGene (2219)   
Protein sequence (16)   
   UniProt (4)   
   SWISS-PROT (3)   
   RefSeq(pep) (6)   
   PDBSTR (2)   
   PMD (1)   
DNA sequence (8)   
   RefSeq(nuc) (7)   
   GenBank (1)   
3D Structure (2)   
   PDB (2)   
Protein domain (1)   
   PROSITE(DOC) (1)   
All databases (2443)   

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