KEGG ENZYME: 3.4.17.15

ENZYME: 3.4.17.15

Entry

EC 3.4.17.15 Enzyme

Name

carboxypeptidase A2;
CPA2

Class

Hydrolases;
Acting on peptide bonds (peptidases);
Metallocarboxypeptidases

Reaction(IUBMB)

Similar to that of carboxypeptidase A (EC 3.4.17.1), but with a preference for bulkier C-terminal residues

Comment

Isolated from rat pancreas but not present in cattle pancreas. In peptidase family M14 (carboxypeptidase A family).

History

EC 3.4.17.15 created 1992

Orthology

K01298

carboxypeptidase A2

Genes

HSA:	1358(CPA2)

PTR:	742070(CPA2)

PPS:	100983954(CPA2)

GGO:	101152905(CPA2)

PON:	100458672(CPA2)

NLE:	100603285(CPA2)

MCC:	706684(CPA2)

MCF:	102130332(CPA2)

CSAB:

103226899(CPA2)

RRO:	104674462(CPA2)

RBB:	108531579(CPA2)

CJC:	100394759(CPA2)

SBQ:	101041379(CPA2)

MMU:	232680(Cpa2)

RNO:	296959(Cpa2)

CGE:	100756609(Cpa2)

NGI:	103744539(Cpa2)

HGL:	101700104(Cpa2)

CCAN:

109699195(Cpa2)

OCU:	100349998(CPA2)

TUP:	102489569(CPA2)

CFA:	475193(CPA2)

AML:	100478542(CPA2)

UMR:	103676659(CPA2)

ORO:	101377290(CPA2)

FCA:	101088825(CPA2)

PTG:	102964595(CPA2)

AJU:	106973910(CPA2)

SSC:	100516306(CPA2)

CFR:	102506813(CPA2)

CDK:	105085436(CPA2)

BACU:

103017822(CPA2)

LVE:	103072366(CPA2)

OOR:	101271769(CPA2)

ECB:	100071976(CPA2)

EPZ:	103546308(CPA2)

EAI:	106839552(CPA2)

MYB:	102252999(CPA2)

MYD:	102774890(CPA2)

HAI:	109384648(CPA2)

RSS:	109457289(CPA2)

PALE:

102890562(CPA2)

LAV:	100670502(CPA2)

TMU:

101350660

SHR:	100931516 105750808

OAA:	100075672(CPA2)

GGA:	416682(CPA2)

MGP:	100544216(CPA2)

CJO:

107311052

APLA:

101805104

ACYG:

106038763

TGU:	100223967(CPA2)

SCAN:

103822463

GFR:	102043912(CPA2)

FAB:	101813935(CPA2)

PHI:	102108782(CPA2)

PMAJ:

107204465

CCAE:

111923181

CCW:

104695959

FPG:	101922417(CPA2)

FCH:	102060013(CPA2)

CLV:

102098475

EGZ:	104123449(CPA2)

NNI:	104010474(CPA2)

ACUN:

113491449(CPA2)

AAM:

ASN:

AMJ:

PSS:

CMY:	102943016(CPA2)

CPIC:

101942769(CPA2)

ACS:	100564619(cpa2)

PVT:	110089541(CPA2)

PBI:

PMUR:

GJA:

NPR:

DRE:	431764(cpa4)

SRX:	107707477 107732822 107732823

SANH:

107686633 107686634 107700998

SGH:	107573279 107573291 107575283 107580111

CCAR:

109064543 109075613 109106962 109107513

IPU:

PHYP:

AMEX:

LCO:

MZE:

OLA:

XMA:

PRET:

NFU:

KMR:

LCF:

SDU:

MALB:

SASA:

100195850(cbpa2)

OTW:

SALP:

ELS:

LCM:

BFO:	BRAFLDRAFT_118166 BRAFLDRAFT_166229 BRAFLDRAFT_212027 BRAFLDRAFT_240860

CIN:

100183283

APLC:

110979600 110979627 110984857

SKO:	100367846 100373689

FCD:	110854910 110859269

DPX:	DAPPUDRAFT_194294 DAPPUDRAFT_224487 DAPPUDRAFT_303899 DAPPUDRAFT_59834

ISC:	IscW_ISCW015949 IscW_ISCW023731

TUT:

107359279

HRO:	HELRODRAFT_107037 HELRODRAFT_107038 HELRODRAFT_107039 HELRODRAFT_185228 HELRODRAFT_188933

CRG:	105320968 105326769 105345633

MYI:

110462445

OBI:	106873122 106876015 106882490

LAK:

106166930

SMM:	Smp_088270

EGL:	EGR_10235 EGR_11299

EPA:	110250771 110251757 110254954

ADF:

107350259

PDAM:

113679182 113679185 113686544 113686598

SPIS:

111335353 111335645

SPAR:

SPRG_16360

» show all

Reference

1 [PMID:3182871]

Authors

Gardell SJ, Craik CS, Clauser E, Goldsmith EJ, Stewart CB, Graf M, Rutter WJ

Title

A novel rat carboxypeptidase, CPA2: characterization, molecular cloning, and evolutionary implications on substrate specificity in the carboxypeptidase gene family.

Journal

J Biol Chem 263:17828-36 (1988)

Sequence

[rno:296959]

Other DBs

ExplorEnz - The Enzyme Database:

3.4.17.15

IUBMB Enzyme Nomenclature:

3.4.17.15

ExPASy - ENZYME nomenclature database:

3.4.17.15

BRENDA, the Enzyme Database:

3.4.17.15

CAS:	181186-98-1

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