KEGG   ENZYME: 3.4.21.19Help
Entry
EC 3.4.21.19                Enzyme                                 

Name
glutamyl endopeptidase;
V8 proteinase;
endoproteinase Glu-C;
staphylococcal serine proteinase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Preferential cleavage: Glu!, Asp!
Comment
From Staphylococcus aureus strain V8. In appropriate buffer the specificity is restricted to Glu!. In peptidase family S1 (trypsin family)
History
EC 3.4.21.19 created 1978
Orthology
K01318  glutamyl endopeptidase
Genes
BLI: BL01804(blaSE)
BLD: BLi00340(mpr)
BCE: BC0789
GTN: GTNG_3484
SAU: SA0901(sspA) SA1627(splF)
SAV: SAV1048(sspA) SAV1809(splF)
SAW: SAHV_1041(sspA) SAHV_1794(splF)
SAH: SaurJH1_1130 SaurJH1_1896
SAJ: SaurJH9_1107 SaurJH9_1861
SAM: MW0932(sspA) MW1752(splF)
SAR: SAR1022(sspA) SAR1902(splE)
SAE: NWMN_0918(sspA) NWMN_1701(splF) NWMN_1702(splE)
SAD: SAAV_1817
SUE: SAOV_0994c SAOV_1795(splF)
SUZ: MS7_1006(sspA) MS7_1809
SUX: SAEMRSA15_08800(sspA)
SUW: SATW20_10450(sspA) SATW20_18060(splF) SATW20_18070(splE)
SUG: SAPIG1046
SAUS: SA40_0919(sspA)
SAUU: SA957_0934(sspA)
SAUZ: SAZ172_0989(sspA) SAZ172_1824(splF)
SAUT: SAI1T1_2007410(sspA)
SAUQ: SAI4T8_1007410(sspA)
SAUV: SAI7S6_1007420(sspA) SAI7S6_1013290(splF)
SAUW: SAI5S5_1007380(sspA)
SAUX: SAI6T6_1007390(sspA) SAI6T6_1013250(splF)
SAUY: SAI8T7_1007420(sspA)
SAB: SAB0915c(sspA) SAB1669c(splF)
SUY: SA2981_1003(sspA) SA2981_1764(splF)
SAUB: C248_1073(sspA)
SAUC: CA347_965(sspA)
SAUR: SABB_01014(sspA) SABB_01932(splF) SABB_01933(splE)
SEP: SE1543
SER: SERP1397(sspA)
SEPP: SEB_01530
SEPS: DP17_458(gseA)
SSP: SSP0282
SPAS: STP1_1178
CTC: CTC_00612
AAU: AAur_1625
AMI: Amir_4522
HAU: Haur_1651
RBA: RB4269
 » show all
Taxonomy
Reference
1  [PMID:1012010]
  Authors
Drapeau GR.
  Title
Protease from Staphyloccus aureus.
  Journal
Methods Enzymol 45:469-75 (1976)
DOI:10.1016/S0076-6879(76)45041-3
Reference
2  [PMID:96922]
  Authors
Drapeau GR.
  Title
The primary structure of staphylococcal protease.
  Journal
Can J Biochem 56:534-44 (1978)
Reference
3  [PMID:3306605]
  Authors
Carmona C, Gray GL.
  Title
Nucleotide sequence of the serine protease gene of Staphylococcus aureus, strain V8.
  Journal
Nucleic Acids Res 15:6757 (1987)
DOI:10.1093/nar/15.16.6757
  Sequence
[sau:SA0901]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.21.19
IUBMB Enzyme Nomenclature: 3.4.21.19
ExPASy - ENZYME nomenclature database: 3.4.21.19
BRENDA, the Enzyme Database: 3.4.21.19
CAS: 137010-42-5

DBGET integrated database retrieval system