EC                Enzyme                                 

complement factor D;
C3 proactivator convertase;
properdin factor D esterase;
factor D;
factor D (complement)
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Selective cleavage of Arg!Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor
A component of the alternative pathway of complement activation. This reaction is analogous to the activation of complement component C2 by complement subcomponent C_overbar_1s_. In peptidase family S1 (trypsin family)
EC created 1981
K01334  complement factor D
HSA: 1675(CFD)
PPS: 100968920(CFD)
GGO: 101136498(CFD)
PON: 100936423(CFD)
NLE: 100599422(CFD)
MCC: 721138(CFD)
MCF: 102136571(CFD)
CSAB: 103233571(CFD)
RRO: 104671463(CFD)
RBB: 108537874(CFD)
CJC: 100389630(CFD)
SBQ: 101030841(CFD)
MMU: 11537(Cfd)
MCAL: 110303909(Cfd)
MPAH: 110326960(Cfd)
RNO: 54249(Cfd)
MUN: 110551364(Cfd)
CGE: 100763302(Cfd)
NGI: 103737401(Cfd)
HGL: 106007830(Cfd)
CCAN: 109693669(Cfd)
TUP: 106734227(CFD)
CFA: 485095(CFD)
VVP: 112935509(CFD)
AML: 100483447(CFD)
UAH: 113242706(CFD)
ORO: 101380360(CFD)
FCA: 101093500(CFD)
PPAD: 109257710(CFD)
AJU: 113596379
BTA: 505647(CFD)
BOM: 102275200(CFD)
BBUB: 102411586(CFD)
CHX: 102173560(CFD)
OAS: 101115705(CFD)
SSC: 396877(CFD)
CFR: 102507253(CFD)
CDK: 105106574(CFD)
LVE: 103086658(CFD)
OOR: 101272668(CFD)
DLE: 111170499(CFD)
PCAD: 102995550(CFD)
ECB: 111774154(CFD)
EAI: 106834238(CFD)
MYD: 102756294(CFD)
MNA: 107538545(CFD)
HAI: 109390585(CFD)
DRO: 112312287
PALE: 102897797(CFD)
RAY: 107500957(CFD)
MJV: 108395527(CFD)
LAV: 100672291(CFD)
TMU: 101356637
SHR: 100928352
PCW: 110196242(CFD)
OAA: 791100(CFD)
GGA: 100857593(CFD)
MGP: 100541228(CFD)
CJO: 107325464(CFD)
NMEL: 110388819(CFD)
APLA: 113845674
TGU: 100224290
LSR: 110475732
SCAN: 103822039
GFR: 102036496(CFD)
FAB: 101807799(CFD)
PHI: 102114080(CFD)
PMAJ: 107215597
CCAE: 111940403
CCW: 104697052(CFD)
ETL: 114066373(CFD)
FPG: 101921526(CFD)
FCH: 102048162(CFD)
CLV: 106145861(CFD)
NNI: 104016308(CFD)
AAM: 106484250(CFD)
ASN: 102381206
AMJ: 102567707(CFD)
PSS: 112545587
CMY: 102931053(CFD)
CPIC: 101935732(CFD)
PVT: 110072602(CFD)
PBI: 103066225
PMUR: 107282291(CFD)
TSR: 106542872
PMUA: 114588305(CFD)
GJA: 107120759(CFD)
XLA: 494791(cfd.L)
XTR: 394945(cfd)
NPR: 108798700
DRE: 553553(cfd)
SRX: 107733667
IPU: 100862744
PHYP: 113544922
AMEX: 103044529
EEE: 113579255
TRU: 101070023
LCO: 104926791
NCC: 104963116
MZE: 101478226
ONL: 100692083
OLA: 100049308(olklklp)
XMA: 102225583
XCO: 114134801
PRET: 103458165
CVG: 107087104
NFU: 107373416
KMR: 108250570
ALIM: 106519943
AOCE: 111580112
CSEM: 103383188
POV: 109640960
LCF: 108889155
SDU: 111225539
SLAL: 111646789
HCQ: 109511554
BPEC: 110155605
MALB: 109962455
SASA: 101448046
OTW: 112265777
SALP: 112075441
ELS: 105015868
SFM: 108919827
PKI: 111860508
 » show all
1  [PMID:6918766]
Reid KB, Johnson DM, Gagnon J, Phohaska R.
Preparation of human factor D of the alternative pathway of complement.
Methods Enzymol 80 Pt C:134-43 (1981)
2  [PMID:3052276]
Muller-Eberhard HJ.
Molecular organization and function of the complement system.
Annu Rev Biochem 57:321-47 (1988)
Other DBs
ExplorEnz - The Enzyme Database:
IUBMB Enzyme Nomenclature:
ExPASy - ENZYME nomenclature database:
BRENDA, the Enzyme Database:
CAS: 37213-56-2

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