Entry |
|
Name |
plasmin;
fibrinase;
fibrinolysin;
actase;
serum tryptase;
thrombolysin
|
Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
 |
Reaction(IUBMB) |
Preferential cleavage: Lys! > Arg!; higher selectivity than trypsin. Converts fibrin into soluble products
|
Comment |
Formed from plasminogen by proteolysis which results in multiple forms of the active plasmin. In peptidase family S1 (trypsin family).
|
History |
EC 3.4.21.7 created 1961 as EC 3.4.4.14, transferred 1972 to EC 3.4.21.7
|
Orthology |
|
Genes |
» show all
 |
Reference |
|
Authors |
Castellino FJ, Sodetz JM. |
Title |
Rabbit plasminogen and plasmin isozymes. |
Journal |
|
Reference |
|
Authors |
Castellino FJ, Powell JR. |
Title |
Human plasminogen. |
Journal |
Methods Enzymol 80 Pt C:365-78 (1981) |
Reference |
|
Authors |
Robbins KC, Summaria L, Wohl RC. |
Title |
Human plasmin. |
Journal |
Methods Enzymol 80 Pt C:379-87 (1981) |
Other DBs |
ExplorEnz - The Enzyme Database: | 3.4.21.7 |
ExPASy - ENZYME nomenclature database: | 3.4.21.7 |
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