KEGG   ENZYME: 3.4.21.71Help
Entry
EC 3.4.21.71                Enzyme                                 

Name
pancreatic elastase II;
pancreatic elastase 2
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Preferential cleavage: Leu!, Met! and Phe!. Hydrolyses elastin
Comment
A peptidase of family S1 (trypsin family) formed by activation of proelastase II from mammalian pancreas by trypsin. Usually, only one of the pancreatic elastases (see also EC 3.4.21.36) is expressed in a given species; human pancreatic elastase is of type II
History
EC 3.4.21.71 created 1992
Orthology
K01346  pancreatic elastase II
Genes
HSA: 51032(CELA2B) 63036(CELA2A)
PTR: 469129 747215(CELA2A)
PPS: 100992916(CELA2A) 100993275(CELA2B)
GGO: 101130048 101137272
PON: 100435271 100461933 100462303
NLE: 100596831 100597738
MCC: 106992406 694691
MCF: 102127568(CELA2A) 102135496(CELA2B) 102139003
CSAB: 103225552(CELA2B) 103247268 103247269
RRO: 104667588 104677706 104677707
CJC: 100395953(CELA2A)
SBQ: 101051841(CELA2A)
MMU: 13706(Cela2a)
MPAH: 110323557
RNO: 24332(Cela2a)
MUN: 110545075
NGI: 103725345
HGL: 101723601(Cela2a)
OCU: 100344955(CELA2A)
TUP: 102494723(CELA2A)
BTA: 282687(CELA2A)
BOM: 102279793(CELA2A)
BIU: 109570435
BBUB: 102411682
CHX: 102174414(CELA2A)
OAS: 101111210
SSC: 397197(CELA2A)
CFR: 102519577(CELA2A)
CDK: 105107055
BACU: 103001724(CELA2A)
LVE: 103078282(CELA2A)
OOR: 101288479
DLE: 111187065
PCAD: 102975160
ECB: 100050670
EPZ: 103565017(CELA2A)
EAI: 106828007
MYB: 102250420(CELA2A)
MYD: 102759032(CELA2A)
MNA: 107531541
HAI: 109381303
DRO: 112299499
PALE: 102878826
RAY: 107501831
MDO: 100027354(CELA2A)
OAA: 100092350
GGA: 419486(CELA2A)
MGP: 100542763
CJO: 107323376
NMEL: 110408541
APLA: 101794015
ACYG: 106040201
TGU: 100224543
SCAN: 103820951
GFR: 102039268
FAB: 101816473
PMAJ: 107213766
CCAE: 111938716
CCW: 104693361
FPG: 101912600
FCH: 102057855
CLV: 102089151
NNI: 104009005
ACUN: 113477290
AAM: 106482438
ACS: 103279433
DRE: 334304(ela2l)
AMEX: 103036513
OBI: 106868563
PDAM: 113668113
VFI: VF_A0273
 » show all
Taxonomy
Reference
1  [PMID:3427074]
  Authors
Fletcher TS, Shen WF, Largman C.
  Title
Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA.
  Journal
Biochemistry 26:7256-61 (1987)
  Sequence
[hsa:63036]
Reference
2  [PMID:2834346]
  Authors
Shirasu Y, Yoshida H, Matsuki S, Takemura K, Ikeda N, Shimada Y, Ozawa T, Mikayama T, Iijima H, Ishida A, et al.
  Title
Molecular cloning and expression in Escherichia coli of a cDNA encoding human pancreatic elastase 2.
  Journal
J Biochem (Tokyo) 102:1555-63 (1987)
  Sequence
[hsa:63036] [ssc:397197]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.21.71
IUBMB Enzyme Nomenclature: 3.4.21.71
ExPASy - ENZYME nomenclature database: 3.4.21.71
BRENDA, the Enzyme Database: 3.4.21.71
CAS: 75603-19-9

DBGET integrated database retrieval system