KEGG   ENZYME: 3.4.21.71Help
Entry
EC 3.4.21.71                Enzyme                                 

Name
pancreatic elastase II;
pancreatic elastase 2
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Preferential cleavage: Leu!, Met! and Phe!. Hydrolyses elastin
Comment
A peptidase of family S1 (trypsin family) formed by activation of proelastase II from mammalian pancreas by trypsin. Usually, only one of the pancreatic elastases (see also EC 3.4.21.36) is expressed in a given species; human pancreatic elastase is of type II
History
EC 3.4.21.71 created 1992
Orthology
K01346  pancreatic elastase II
Genes
HSA: 51032(CELA2B) 63036(CELA2A)
PTR: 469129 747215(CELA2A)
PPS: 100992916(CELA2A) 100993275(CELA2B)
GGO: 101130048(CELA2A) 101137272(CELA2B)
PON: 100435271 100461933 100462303
NLE: 100596831(CELA2A) 100597738(CELA2B)
MCC: 106992406 694691(ELA2A)
MCF: 102127568(CELA2A) 102135496(CELA2B) 102139003
CSAB: 103225552(CELA2B) 103247268 103247269
RRO: 104667588 104677705 104677706 104677707
CJC: 100395953(CELA2A)
SBQ: 101051841(CELA2A)
MMU: 13706(Cela2a)
RNO: 24332(Cela2a)
CGE: 100753261(Cela2a) 103161926
NGI: 103725345
HGL: 101723601(Cela2a)
OCU: 100344955(CELA2A)
TUP: 102494723(CELA2A)
BTA: 282687(CELA2A)
BOM: 102279793(CELA2A)
BIU: 109570435
PHD: 102335848(CELA2A)
CHX: 102174414(CELA2A)
OAS: 101111210
SSC: 397197(CELA2A)
CFR: 102519577(CELA2A)
CDK: 105107055(CELA2A)
BACU: 103001724(CELA2A)
LVE: 103078282(CELA2A)
OOR: 101288479
ECB: 100050670
EPZ: 103565017(CELA2A)
EAI: 106828007
MYB: 102250420(CELA2A)
MYD: 102759032(CELA2A)
HAI: 109381303
RSS: 109459001
PALE: 102878826
MDO: 100027354(CELA2A)
OAA: 100092350
GGA: 419486(CELA2A)
MGP: 100542763
CJO: 107323376
APLA: 101794015
ACYG: 106040201
TGU: 100224543(CELA2A)
GFR: 102039268
FAB: 101816473
PMAJ: 107213766
CCAE: 111938716
CCW: 104693361
FPG: 101912600
FCH: 102057855
CLV: 102089151
AAM: 106482438
ACS: 103279433
DRE: 334304(ela2l)
AMEX: 103036513
APLC: 110984931
TUT: 107371020
TSP: Tsp_09087
CRG: 105317979
OBI: 106868563
EPA: 110253768
VFI: VF_A0273
 » show all
Taxonomy
Reference
1  [PMID:3427074]
  Authors
Fletcher TS, Shen WF, Largman C.
  Title
Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA.
  Journal
Biochemistry 26:7256-61 (1987)
  Sequence
[hsa:63036]
Reference
2  [PMID:2834346]
  Authors
Shirasu Y, Yoshida H, Matsuki S, Takemura K, Ikeda N, Shimada Y, Ozawa T, Mikayama T, Iijima H, Ishida A, et al.
  Title
Molecular cloning and expression in Escherichia coli of a cDNA encoding human pancreatic elastase 2.
  Journal
J Biochem (Tokyo) 102:1555-63 (1987)
  Sequence
[hsa:63036] [ssc:397197]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.21.71
IUBMB Enzyme Nomenclature: 3.4.21.71
ExPASy - ENZYME nomenclature database: 3.4.21.71
BRENDA, the Enzyme Database: 3.4.21.71
CAS: 75603-19-9

DBGET integrated database retrieval system