KEGG   ENZYME: 3.4.22.16Help
Entry
EC 3.4.22.16                Enzyme                                 

Name
cathepsin H;
cathepsin B3;
benzoylarginine-naphthylamide (BANA) hydrolase (obsolete);
cathepsin Ba, aleurain;
N-benzoylarginine-beta-naphthylamide hydrolase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg! bonds) as well as an endopeptidase
Comment
Present in lysosomes of mammalian cells. In peptidase family C1 (papain family)
History
EC 3.4.22.16 created 1981, modified 1989
Orthology
K01366  cathepsin H
Genes
HSA: 1512(CTSH)
PTR: 740462(CTSH)
PPS: 100994578(CTSH)
GGO: 101144312(CTSH)
PON: 100460934(CTSH)
NLE: 100584322(CTSH)
MCC: 711437(CTSH)
MCF: 102115935(CTSH)
CSAB: 103245241(CTSH)
RRO: 104675185(CTSH)
RBB: 108538647(CTSH)
CJC: 100413104(CTSH)
SBQ: 101038067(CTSH)
MMU: 13036(Ctsh)
RNO: 25425(Ctsh)
CGE: 100756691(Ctsh)
NGI: 103726016(Ctsh)
HGL: 101700582(Ctsh)
CCAN: 109697210(Ctsh)
OCU: 100101597(CTSH)
TUP: 102483972(CTSH)
CFA: 479065(CTSH)
AML: 100481013(CTSH)
UMR: 103660296(CTSH)
ORO: 101362840(CTSH)
FCA: 101092687(CTSH)
PTG: 102969753(CTSH)
AJU: 106988474(CTSH)
BTA: 510524(CTSH)
BOM: 102281958(CTSH)
BIU: 109575407(CTSH)
PHD: 102321273(CTSH)
CHX: 102170638(CTSH)
OAS: 101108427(CTSH)
SSC: 396969(CTSH)
CFR: 102524291(CTSH)
CDK: 105092231(CTSH)
BACU: 103019787(CTSH)
LVE: 103084230(CTSH)
OOR: 101287575(CTSH)
ECB: 100059835(CTSH)
EPZ: 103559011(CTSH)
EAI: 106840814(CTSH)
MYB: 102242799(CTSH)
MYD: 102754763(CTSH)
HAI: 109381379(CTSH)
PALE: 102897634(CTSH)
LAV: 100662496(CTSH)
TMU: 101361718
MDO: 100014210(CTSH)
SHR: 100926518(CTSH)
GGA: 770109(CTSH)
MGP: 100551376(CTSH)
CJO: 107318952(CTSH)
APLA: 101804912(CTSH)
ACYG: 106048660(CTSH)
TGU: 100232804(CTSH)
GFR: 102036092(CTSH)
FAB: 101811077(CTSH)
PHI: 102108387(CTSH)
PMAJ: 107209076(CTSH)
CCAE: 111933844
CCW: 104684052(CTSH)
FPG: 101922144(CTSH)
FCH: 102057998(CTSH)
CLV: 102087477(CTSH)
EGZ: 104122478(CTSH)
AAM: 106487037(CTSH)
ASN: 102384797(CTSH)
AMJ: 102564481(CTSH)
PSS: 102458148(CTSH)
CMY: 102938471(CTSH)
CPIC: 101936196(CTSH)
ACS: 100561600(ctsh)
PVT: 110091401(CTSH)
PBI: 103061128
GJA: 107125357(CTSH)
DRE: 324818(ctsh)
SRX: 107715232(ctsh)
SGH: 107551467(ctsh) 107556249
IPU: 100305012(ctsh)
AMEX: 103040728 103043563(ctsh)
TRU: 101078766(ctsh)
LCO: 104917829(ctsh) 104940230
MZE: 101468200(ctsh) 101475779
OLA: 111947539(ctsh)
XMA: 102227764(ctsh)
PRET: 103466621(ctsh)
NFU: 107388794(ctsh)
KMR: 108230028(ctsh) 108237393
CSEM: 103379443(ctsh)
MALB: 109967274(ctsh)
SASA: 106561173(CATH) 106562440(CATH) 106573516
ELS: 105025674(ctsh)
SFM: 108931675(ctsh)
LCM: 102358878(CTSH)
CMK: 103186362(ctsh)
CIN: 100184721
SKO: 100370397
ATH: AT3G45310 AT5G60360(ALP)
THJ: 104814838
CPAP: 110817702
CIT: 102578016
TCC: 18588277
CAM: 101510518
LJA: Lj4g3v2203610.1(Lj4g3v2203610.1)
FVE: 101297079
PPER: 18770752
PMUM: 103340590
PAVI: 110749196
ZJU: 107423924
CSV: 101209045
CMO: 103492370
MCHA: 111016585
RCU: 8281173
JCU: 105637967
POP: 18100334
JRE: 109008520
VVI: 100244107
SLY: 101252200 101252505(Cyp-3)
CANN: 107877862(cyp-3)
INI: 109193112
CCAV: 112516574
DCR: 108199861
BVG: 104883466
SOE: 110805191
NNU: 104600548
OSA: 4347180
DOSA: Os09t0442300-01(Os09g0442300)
OBR: 102702127
BDI: 100833741
ATS: 109751542(LOC109751542)
SBI: 8062751
ZMA: 542451(ccp2)
SITA: 101765887
ATR: 18439478
PPP: 112286849
SPAR: SPRG_12173
 » show all
Taxonomy
Reference
1  [PMID:7043200]
  Authors
Barrett AJ, Kirschke H.
  Title
Cathepsin B, Cathepsin H, and cathepsin L.
  Journal
Methods Enzymol 80 Pt C:535-61 (1981)
Reference
2  [PMID:3663163]
  Authors
Bromme D, Bescherer K, Kirschke H, Fittkau S.
  Title
Enzyme-substrate interactions in the hydrolysis of peptides by cathepsins B and H from rat liver.
  Journal
Biochem J 245:381-5 (1987)
Reference
3  [PMID:2849458]
  Authors
Fuchs R, Machleidt W, Gassen HG.
  Title
Molecular cloning and sequencing of a cDNA coding for mature human kidney cathepsin H.
  Journal
Biol Chem Hoppe Seyler 369:469-75 (1988)
  Sequence
[hsa:1512]
Other DBs
ExplorEnz - The Enzyme Database: 3.4.22.16
IUBMB Enzyme Nomenclature: 3.4.22.16
ExPASy - ENZYME nomenclature database: 3.4.22.16
BRENDA, the Enzyme Database: 3.4.22.16
CAS: 60748-73-4

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