KEGG   ENZYME: 3.4.22.26Help
Entry
EC 3.4.22.26                Enzyme                                 

Name
cancer procoagulant
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Specific cleavage of Arg!Ile bond in Factor X to form Factor Xa
Comment
Apparently produced only by malignant and fetal cells
History
EC 3.4.22.26 created 1992
Reference
1  [PMID:3935163]
  Authors
Falanga A, Gordon SG.
  Title
Isolation and characterization of cancer procoagulant: a cysteine proteinase from malignant tissue.
  Journal
Biochemistry 24:5558-67 (1985)
Reference
2  [PMID:2772865]
  Authors
Falanga A, Shaw E, Donati MB, Consonni R, Barbui T, Gordon S.
  Title
Inhibition of cancer procoagulant by peptidyl diazomethyl ketones and peptidyl sulfonium salts.
  Journal
Thromb Res 54:389-98 (1989)
DOI:10.1016/0049-3848(89)90209-0
Other DBs
ExplorEnz - The Enzyme Database: 3.4.22.26
IUBMB Enzyme Nomenclature: 3.4.22.26
ExPASy - ENZYME nomenclature database: 3.4.22.26
BRENDA, the Enzyme Database: 3.4.22.26
CAS: 109456-80-6

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