Entry |
|
Name |
pepsin B;
parapepsin I;
pig gelatinase
|
Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Aspartic endopeptidases
|
Reaction(IUBMB) |
Degradation of gelatin; little activity on hemoglobin. Specificity on B chain of insulin more restricted than that of pepsin A; does not cleave at Phe1-Val, Gln4-His or Gly23-Phe
|
Comment |
Formed from pig pepsinogen B. In peptidase family A1 (pepsin A family)
|
History |
EC 3.4.23.2 created 1961 as EC 3.4.4.2, transferred 1972 to EC 3.4.23.2, modified 1986
|
Reference |
1 |
Authors |
Ryle, A.P. |
Title |
The porcine pepsins and pepsinogens. |
Journal |
Methods Enzymol 19:316-336 (1970) |
Other DBs |
ExplorEnz - The Enzyme Database: | 3.4.23.2 |
ExPASy - ENZYME nomenclature database: | 3.4.23.2 |
|