KEGG   ENZYME: 3.4.23.40Help
Entry
EC 3.4.23.40                Enzyme                                 

Name
phytepsin
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Aspartic endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Prefers hydrophobic residues Phe, Val, Ile, Leu, and Ala at P1 and P1', but also cleaves -Phe!Asp- and -Asp!Asp- bonds in 2S albumin from plant seeds
Comment
Known particularly from barley grain, but present in other plants also. In peptidase family A1 (pepsin A family), but structurally distinct in containing an internal region of about 100 amino acids not generally present in the family
History
EC 3.4.23.40 created 1997
Orthology
K08245  phytepsin
Genes
RSS: 109440642 109441186 109441237
ATH: AT1G11910(APA1) AT1G62290 AT4G04460
ALY: ARALYDRAFT_314946 ARALYDRAFT_471340 ARALYDRAFT_475117 ARALYDRAFT_490093
CRB: 17881324 17895239 17896448 17898275 17900186
CSAT: 104701092 104701093 104703829 104714562 104716987 104731313 104733402 104733403 104737288 104739839 104752884 104755449 104759012 104759013 104770715 104773448 104774633 104787437 104787438 109125180 109131876
EUS: EUTSA_v10007418mg EUTSA_v10023414mg EUTSA_v10028587mg
BRP: 103836199 103838666 103839838 103843214 103848160 103858657
BNA: 106362176 106366922 106368609 106376996 106396368 106413636 106415098 106415178 106434262 106435833 106438757 106442725 106442742 111204471
BOE: 106294431 106311623 106311961 106312989 106319225 106329520 106337618
THJ: 104806312 104809490 104813344 104818674 104820456 104823533
LJA: Lj0g3v0077119.1(Lj0g3v0077119.1) Lj0g3v0080919.1(Lj0g3v0080919.1) Lj0g3v0080919.2(Lj0g3v0080919.2) Lj0g3v0254609.1(Lj0g3v0254609.1) Lj0g3v0282749.3(Lj0g3v0282749.3) Lj1g3v4807400.1(Lj1g3v4807400.1) Lj3g3v1312770.1(Lj3g3v1312770.1) Lj4g3v0135640.1(Lj4g3v0135640.1) Lj4g3v0135640.2(Lj4g3v0135640.2) Lj4g3v0135640.3(Lj4g3v0135640.3) Lj4g3v0137730.1(Lj4g3v0137730.1)
DOSA: Os01t0290000-01(Os01g0290000) Os01t0631900-00(Os01g0631900) Os01t0663400-01(Os01g0663400) Os05t0137400-01(Os05g0137400) Os05t0567100-01(Os05g0567100)
ATS: 109739751(LOC109739751) 109742347(LOC109742347) 109748912(LOC109748912) 109749282(LOC109749282) 109761984(LOC109761984) 109771027(LOC109771027)
MNG: MNEG_6205
APRO: F751_0309
SMIN: v1.2.028921.t1(symbB.v1.2.028921.t1)
 » show all
Taxonomy
Reference
1  [PMID:1722454]
  Authors
Runeberg-Roos P, Tormakangas K, Ostman A.
  Title
Primary structure of a barley-grain aspartic proteinase. A plant aspartic proteinase resembling mammalian cathepsin D.
  Journal
Eur J Biochem 202:1021-7 (1991)
DOI:10.1111/j.1432-1033.1991.tb16465.x
  Sequence
Reference
2  [PMID:7763475]
  Authors
Kervinen J, Sarkkinen P, Kalkkinen N, Mikola L, Saarma M.
  Title
Hydrolytic specificity of the barley grain aspartic proteinase.
  Journal
Phytochemistry 32:799-803 (1993)
DOI:10.1016/0031-9422(93)85208-9
Reference
3  [PMID:7556174]
  Authors
Asakura T, Watanabe H, Abe K, Arai S.
  Title
Rice aspartic proteinase, oryzasin, expressed during seed ripening and germination, has a gene organization distinct from those of animal and microbial aspartic proteinases.
  Journal
Eur J Biochem 232:77-83 (1995)
DOI:10.1111/j.1432-1033.1995.tb20783.x
  Sequence
[osa:4339639]
Reference
4  [PMID:8540324]
  Authors
Kervinen J, Tormakangas K, Runeberg-Roos P, Guruprasad K, Blundell T, Teeri TH.
  Title
Structure and possible function of aspartic proteinases in barley and other plants.
  Journal
Adv Exp Med Biol 362:241-54 (1995)
Other DBs
ExplorEnz - The Enzyme Database: 3.4.23.40
IUBMB Enzyme Nomenclature: 3.4.23.40
ExPASy - ENZYME nomenclature database: 3.4.23.40
BRENDA, the Enzyme Database: 3.4.23.40
CAS: 219715-98-7

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