KEGG   ENZYME: 3.4.24.22Help
Entry
EC 3.4.24.22                Enzyme                                 

Name
stromelysin 2;
matrix metalloproteinase 10;
transin 2;
proteoglycanase 2
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
BRITE hierarchy
Reaction(IUBMB)
Similar to stromelysin 1, but action on collagen types III, IV and V is weak
Comment
In peptidase family M10 (interstitial collagenase family). Digests gelatin types I, III, IV, V, fibronectin and proteoglycan
History
EC 3.4.24.22 created 1992
Orthology
K01396  matrix metalloproteinase-10 (stromelysin 2)
Genes
HSA: 4319(MMP10)
PTR: 740658(MMP10)
PPS: 100996180(MMP10)
GGO: 101131626(MMP10)
PON: 100460793(MMP10)
NLE: 100583748(MMP10)
MCC: 701793(MMP10)
MCF: 102142363(MMP10)
CSAB: 103248336(MMP10)
RRO: 104674664(MMP10)
RBB: 108514075(MMP10)
CJC: 100395869(MMP10)
SBQ: 101051882(MMP10)
MMU: 17384(Mmp10)
RNO: 117061(Mmp10)
CGE: 100755142(Mmp10)
NGI: 103731570(Mmp10)
HGL: 101697990(Mmp10)
CCAN: 109689287(Mmp10)
OCU: 100101603(MMP10)
ORO: 101369596(MMP10)
FCA: 101081247(MMP10)
PTG: 102951156
AJU: 106976488(MMP10)
ECB: 100146442
MYD: 102753365(MMP10)
RSS: 109437749
PALE: 102885902(MMP10)
LAV: 100660014(MMP10)
TMU: 101341774
XTR: 594917(mmp3)
 » show all
Taxonomy
Reference
1  [PMID:3547333]
  Authors
Breathnach R, Matrisian LM, Gesnel MC, Staub A, Leroy P.
  Title
Sequences coding for part of oncogene-induced transin are highly conserved in a related rat gene.
  Journal
Nucleic Acids Res 15:1139-51 (1987)
DOI:10.1093/nar/15.3.1139
  Sequence
[rno:117061]
Reference
2  [PMID:2844164]
  Authors
Muller D, Quantin B, Gesnel MC, Millon-Collard R, Abecassis J, Breathnach R.
  Title
The collagenase gene family in humans consists of at least four members.
  Journal
Biochem J 253:187-92 (1988)
  Sequence
[hsa:4319]
Reference
3  [PMID:2548603]
  Authors
Nicholson R, Murphy G, Breathnach R.
  Title
Human and rat malignant-tumor-associated mRNAs encode stromelysin-like metalloproteinases.
  Journal
Biochemistry 28:5195-203 (1989)
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.22
IUBMB Enzyme Nomenclature: 3.4.24.22
ExPASy - ENZYME nomenclature database: 3.4.24.22
BRENDA, the Enzyme Database: 3.4.24.22
CAS: 140610-48-6

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