KEGG   ENZYME: 3.4.24.77Help
Entry
EC 3.4.24.77                Enzyme                                 

Name
snapalysin;
small neutral protease;
SnpA gene product (Streptomyces lividans)
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
BRITE hierarchy
Reaction(IUBMB)
Hydrolyses proteins with a preference for Tyr or Phe in the P1' position. Has no action on amino-acid p-nitroanilides
Comment
Type example of peptidase family M7.
History
EC 3.4.24.77 created 2001
Orthology
K01416  snapalysin
Genes
SCO: SCO7432(mprA2) SCO7635(SC10F4.08c)
SALB: XNR_2637 XNR_3916
SMA: SAVERM_2939 SAVERM_4407
SGR: SGR_268 SGR_6685
SGB: WQO_00475 WQO_24175 WQO_33250
SCB: SCAB_6381(snp3)
SSX: SACTE_2215 SACTE_4489
SVL: Strvi_1582 Strvi_3679
SCT: SCAT_p1641
SCY: SCATT_p00810
SHY: SHJG_8419
SDV: BN159_4362(snpA)
SFI: SFUL_5071
SGU: SGLAU_01885(snp3)
SLD: T261_2781
STRM: M444_23095
SPRI: SPRI_2624
SRW: TUE45_pSRc_0553(snpA)
SRN: A4G23_03866(snpA)
SNR: SNOUR_15165(snpA)
SLAU: SLA_5089
SALJ: SMD11_4739
SLX: SLAV_13325(snpA)
KSK: KSE_69520(snpA)
KFL: Kfla_5505
NDA: Ndas_1709
SRO: Sros_5806
SEN: SACE_1316(snp3)
AMI: Amir_2386
SAQ: Sare_3037
MIL: ML5_1348
AFS: AFR_06010
CAI: Caci_2739
 » show all
Taxonomy
Reference
1
  Authors
Kurisu, G., Sugimoto, A., Harada, S., Takagi, M., Imanaka, T. and Kai, Y.
  Title
Characterization of a small metalloprotease from Streptomyces caespitosus with high specificity to aromatic residues.
  Journal
J Ferment Bioeng 83:590-592 (1997)
Reference
2
  Authors
Butler, M.J.
  Title
Snapalysin.
  Journal
In: Barrett, A.J., Rawlings, N.D. and Woessner, J.F. (Eds.), Handbook of Proteolytic Enzymes, Handbook of Proteolytic Enzymes, London, 1998, p. 1134-1135.
Reference
3  [PMID:11132632]
  Authors
Kurisu G, Kai Y, Harada S.
  Title
Structure of the zinc-binding site in the crystal structure of a zinc endoprotease from Streptomyces caespitosus at 1 A resolution.
  Journal
J Inorg Biochem 82:225-8 (2000)
DOI:10.1016/S0162-0134(00)00136-7
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.77
IUBMB Enzyme Nomenclature: 3.4.24.77
ExPASy - ENZYME nomenclature database: 3.4.24.77
BRENDA, the Enzyme Database: 3.4.24.77
CAS: 945859-47-2

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