KEGG   ENZYME: 3.5.1.105Help
Entry
EC 3.5.1.105                Enzyme                                 

Name
chitin disaccharide deacetylase;
chitobiose amidohydolase;
COD;
chitin oligosaccharide deacetylase;
chitin oligosaccharide amidohydolase;
2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-D-glucopyranose acetylhydrolase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
N,N'-diacetylchitobiose acetylhydrolase
Reaction(IUBMB)
N,N'-diacetylchitobiose + H2O = N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine + acetate [RN:R11889]
Reaction(KEGG)
Substrate
N,N'-diacetylchitobiose [CPD:C01674];
H2O [CPD:C00001]
Product
N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine [CPD:C21747];
acetate [CPD:C00033]
Comment
Chitin oligosaccharide deacetylase is a key enzyme in the chitin catabolic cascade of chitinolytic Vibrio strains. Besides being a nutrient, the heterodisaccharide product 4-O-(N-acetyl-beta-D-glucosaminyl)-D-glucosamine is a unique inducer of chitinase production in Vibrio parahemolyticus [2]. In contrast to EC 3.5.1.41 (chitin deacetylase) this enzyme is specific for the chitin disaccharide [1,3]. It also deacetylates the chitin trisaccharide with lower efficiency [3]. No activity with higher polymers of GlcNAc [1,3].
History
EC 3.5.1.105 created 2010
Orthology
K03478  chitin disaccharide deacetylase
K18454  chitin disaccharide deacetylase
Genes
ECO: b1733(chbG)
ECJ: JW1722(chbG)
ECD: ECDH10B_1871(chbG)
EBW: BWG_1546(chbG)
ECOK: ECMDS42_1408(chbG)
ECE: Z2763(ydjC)
ECS: ECs2439
ECF: ECH74115_2451
ETW: ECSP_2301(chbG)
ELX: CDCO157_2273
EOJ: ECO26_2508(chbG)
EOI: ECO111_2244(chbG)
EOH: ECO103_1926(chbG)
ECOO: ECRM13514_2230(ydjC)
ECOH: ECRM13516_2135(ydjC)
ECG: E2348C_1861(chbG)
EOK: G2583_2179(chbG)
ESO: O3O_14320
ESM: O3M_11280
ESL: O3K_11300
ELH: ETEC_1765
ECC: c2132(ydjC)
ECP: ECP_1679
ECI: UTI89_C1926(ydjC)
ECV: APECO1_802(ydjC)
ECY: ECSE_1903
ECR: ECIAI1_1793(chbG)
ECQ: ECED1_1935(chbG)
ECK: EC55989_1901(chbG)
ECT: ECIAI39_1321(chbG)
EUM: ECUMN_2022(chbG)
ECZ: ECS88_1785(chbG)
ELO: EC042_1898(chbG)
ESE: ECSF_1594
EBR: ECB_01702(ydjC)
EBD: ECBD_1912
EAB: ECABU_c19890(ydjC)
EDJ: ECDH1ME8569_1677(chbG)
ENA: ECNA114_1778(ydjC)
ELW: ECW_m1902(chbG)
ELL: WFL_09325
ELC: i14_1952(ydjC)
ELD: i02_1952(ydjC)
EBL: ECD_01702(chbG)
EBE: B21_01690(chbG)
ELF: LF82_0294(chbG)
ECOJ: P423_09225
ECOS: EC958_1954(ydjC)
EFE: EFER_1334(chbG)
STY: STY1796
STT: t1196
STM: STM1317(celG)
SEO: STM14_1599(celG)
SEY: SL1344_1252(celG)
SEJ: STMUK_1284(celG)
SEB: STM474_1322(chbg)
SENI: CY43_06705
SPT: SPA1527(celG)
SEK: SSPA1418
SEI: SPC_2413(celG)
SEC: SCH_1338(celG)
SHB: SU5_01936
SENS: Q786_08670
SED: SeD_A2027
SEG: SG1799
SEL: SPUL_1134
SET: SEN1726
SENA: AU38_08935
SENO: AU37_08940
SENV: AU39_08945
SENQ: AU40_09985
SENL: IY59_09140
SEEP: I137_05210
SENE: IA1_06500
SBG: SBG_1171
SBZ: A464_1272
SFL: SF1495(ydjC)
SFX: S1612(ydjC)
SFV: SFV_1487(ydjC)
SFN: SFy_2144
SFS: SFyv_2196
SSN: SSON_1425(ydjC)
ENC: ECL_02434
ECLO: ENC_14330
EEC: EcWSU1_01795(ydjC)
ECLX: LI66_09075
ECLY: LI62_09850
ECLZ: LI64_09140
KPN: KPN_01235(ydjC)
KPU: KP1_2268
KPP: A79E_2951
KPE: KPK_3206
KPJ: N559_3045
KPNU: LI86_15830
KPNK: BN49_2371
KVA: Kvar_3079
KOX: KOX_18220
KOE: A225_2500
EAE: EAE_21530
EAR: CCG29631
CKO: CKO_01758
CRO: ROD_07511(chbG) ROD_13231(chbG)
CAMA: F384_05985
EBF: D782_2540
YPE: YPO2682
YPK: y1255
YPH: YPC_3176
YPA: YPA_2411
YPN: YPN_1168
YPM: YP_2484
YPG: YpAngola_A3572(chbG)
YPZ: YPZ3_2366
YPD: YPD4_2346
YPX: YPD8_2345
YPW: CH59_3562
YPJ: CH55_1489
YPV: BZ15_851
YPL: CH46_2427
YPS: YPTB2927
YPO: BZ17_3701
YPI: YpsIP31758_1095(chbG)
YPY: YPK_1148
YPB: YPTS_3043
YPQ: DJ40_3562
YPU: BZ21_2232
YPR: BZ20_3245
YPC: BZ23_2512
YPF: BZ19_2298
YEN: YE0972
YEY: Y11_42061
YEW: CH47_375
YET: CH48_630
YAL: AT01_3453
YFR: AW19_126
YIN: CH53_711
YKR: CH54_1537
YRO: CH64_1564
YRU: BD65_607
SPE: Spro_0838
SRL: SOD_c07050(chbG)
SPLY: Q5A_003675(chbG)
SMW: SMWW4_v1c08220(chbG)
SMAR: SM39_0157(chbG)
SMAC: SMDB11_0155(chbG)
SERF: L085_00150
RAA: Q7S_23761
PMR: PMI2951(chbG)
PSX: DR96_265
VSC: VSVS12_02688(chbG)
VTA: A0009 A0827
VFI: VF_1341(chbG)
PPR: PBPRA0494(VC1280) PBPRA0498
PFL: PFL_3093
PPRO: PPC_3121
PMAN: OU5_5825
PKC: PKB_2739
PSOS: POS17_3097
SBL: Sbal_1411
SWD: Swoo_0564
CBU: CBU_0580
AVR: B565_2907
PSE: NH8B_4035
RME: Rmet_5852
AAV: Aave_0597
AZO: azo0748
AZA: AZKH_0686
AOA: dqs_0822
DMA: DMR_20950
DGG: DGI_1411
PPRF: DPRO_1953
DAL: Dalk_4316
ADE: Adeh_1624
MXA: MXAN_6314
CCX: COCOR_06930(ydjC1)
MLO: mll3087
AVI: Avi_1930
BJA: blr7527
BRA: BRADO6109
BBT: BBta_1678
BRS: S23_61570
AOL: S58_62960
BRAD: BF49_3060
RPA: RPA1147
RPB: RPB_1843
RPC: RPC_4720
RPD: RPD_4120
RPE: RPE_0869
RPT: Rpal_1338
NWI: Nwi_2568
NHA: Nham_3190
OCA: OCAR_7265
XAU: Xaut_2351
AZC: AZC_1473
SNO: Snov_4401
MET: M446_5304
MNO: Mnod_5902
BID: Bind_1647
MSL: Msil_0374
BVR: BVIR_2711
RMM: ROSMUCSMR3_02843(chbG)
SPHD: HY78_29080
STAX: MC45_05350
RCE: RC1_0150
MAG: amb2281
MAGX: XM1_3102
MAGN: WV31_07880
BLI: BL01636
BLD: BLi00267
BHA: BH0913
BAN: BA_5440
BAR: GBAA_5440
BAT: BAS5055
BAI: BAA_5468
BANT: A16_54530
BANR: A16R_55160
BANS: BAPAT_5217
BANV: DJ46_4099
BCE: BC5208
BCA: BCE_5317
BCZ: BCE33L4900(celC)
BCQ: BCQ_5030(celC)
BCX: BCA_5336
BNC: BCN_5123
BCF: bcf_26045
BCER: BCK_09360
BTL: BALH_4700
BTT: HD73_5610
BTHI: BTK_27575
BTM: MC28_4440
BTI: BTG_22365
BTW: BF38_933
BWW: bwei_4586(celC)
BMYO: BG05_842
BMYC: DJ92_2259
BGY: BGLY_0274
BBEV: BBEV_3098(ydjC)
OIH: OB2271
BSE: Bsel_0181
LMO: lmo0191
LMOE: BN418_0200
LMOB: BN419_0204
LMOD: LMON_0189
LMOW: AX10_09410
LMOM: IJ09_09410
LMP: MUO_01100
LMOX: AX24_13560
LMQ: LMM7_0212
LMS: LMLG_2394
LMOK: CQ02_01025
LWE: lwe0160
LSG: lse_0168
BLR: BRLA_c031950(hpnK)
PSWU: SY83_09930
LSA: LCA_1197
LRL: LC705_00457(celC)
LRA: LRHK_470
EFA: EF3048
EFL: EF62_0125
EFS: EFS1_2483
EFN: DENG_02933(ydjC)
EFQ: DR75_1773
ENE: ENT_27960
EFM: M7W_1485
ECAS: ECBG_01659
CBE: Cbei_4037
CBZ: Cbs_4037
CBEI: LF65_04544
AMT: Amet_4184
CDF: CD630_28810(celG)
PDC: CDIF630_03149(celG)
PDF: CD630DERM_28810(celG)
STH: STH2449
SWO: Swol_2271
DAE: Dtox_2008
DAU: Daud_1261
CTHM: CFE_0783
TTE: TTE0334
THX: Thet_0305
TOC: Toce_0341
SFA: Sfla_0362
SBH: SBI_02868
STRP: F750_6647
SMAL: SMALA_1974
ACIJ: JS278_00342(chbG)
PSEA: WY02_15370
KAL: KALB_5779
AFO: Afer_1607
RCA: Rcas_1066
ATM: ANT_22350
TTR: Tter_2373
GBA: J421_0636
PSAC: PSM36_0029
RMR: Rmar_2484
MUC: MuYL_1607
LBY: Lbys_3372
HSW: Hsw_0822
FJO: Fjoh_0046
IAL: IALB_0194
SALI: L593_00615
 » show all
Taxonomy
Reference
1  [PMID:17334758]
  Authors
Kadokura K, Rokutani A, Yamamoto M, Ikegami T, Sugita H, Itoi S, Hakamata W, Oku T, Nishio T
  Title
Purification and characterization of Vibrio parahaemolyticus extracellular chitinase and chitin oligosaccharide deacetylase involved in the production of heterodisaccharide from chitin.
  Journal
Appl Microbiol Biotechnol 75:357-65 (2007)
DOI:10.1007/s00253-006-0831-6
Reference
2  [PMID:19553519]
  Authors
Hirano T, Kadokura K, Ikegami T, Shigeta Y, Kumaki Y, Hakamata W, Oku T, Nishio T
  Title
Heterodisaccharide 4-O-(N-acetyl-beta-D-glucosaminyl)-D-glucosamine is a specific inducer of chitinolytic enzyme production in Vibrios harboring chitin oligosaccharide deacetylase genes.
  Journal
Glycobiology 19:1046-53 (2009)
DOI:10.1093/glycob/cwp088
  Sequence
Reference
3
  Authors
Ohishi, K., Yamagishi, M., Ohta, T., Motosugi, M., Izumida, H., Sano, H., Adachi, K., Miwa, T.
  Title
Purification and properties of two deacetylases produced by Vibrio alginolyticus H-8.
  Journal
Biosci Biotechnol Biochem 61:1113-1117 (1997)
Reference
4  [PMID:16232910]
  Authors
Ohishi K, Murase K, Ohta T, Etoh H
  Title
Cloning and sequencing of the deacetylase gene from Vibrio alginolyticus H-8.
  Journal
J Biosci Bioeng 90:561-3 (2000)
DOI:10.1016/S1389-1723(01)80041-4
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.105
IUBMB Enzyme Nomenclature: 3.5.1.105
ExPASy - ENZYME nomenclature database: 3.5.1.105
BRENDA, the Enzyme Database: 3.5.1.105

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