KEGG   ENZYME: 3.5.1.74Help
Entry
EC 3.5.1.74                 Enzyme                                 

Name
chenodeoxycholoyltaurine hydrolase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
chenodeoxycholoyltaurine amidohydrolase
Reaction(IUBMB)
chenodeoxycholoyltaurine + H2O = chenodeoxycholate + taurine [RN:R03977]
Reaction(KEGG)
Substrate
chenodeoxycholoyltaurine [CPD:C05465];
H2O [CPD:C00001]
Product
chenodeoxycholate [CPD:C02528];
taurine [CPD:C00245]
Comment
Some other taurine conjugates are hydrolysed, but not glycine conjugates of bile acids.
History
EC 3.5.1.74 created 1992
Pathway
ec00121  Secondary bile acid biosynthesis
Reference
1  [PMID:2628421]
  Authors
Kawamoto K, Horibe I, Uchida K.
  Title
Purification and characterization of a new hydrolase for conjugated bile acids, chenodeoxycholyltaurine hydrolase, from Bacteroides vulgatus.
  Journal
J Biochem (Tokyo) 106:1049-53 (1989)
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.74
IUBMB Enzyme Nomenclature: 3.5.1.74
ExPASy - ENZYME nomenclature database: 3.5.1.74
BRENDA, the Enzyme Database: 3.5.1.74
CAS: 125752-75-2

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