KEGG   ENZYME: 3.5.3.17Help
Entry
EC 3.5.3.17                 Enzyme                                 

Name
guanidinopropionase;
GPase;
GPH
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amidines
BRITE hierarchy
Sysname
3-guanidinopropanoate amidinopropionase
Reaction(IUBMB)
3-guanidinopropanoate + H2O = beta-alanine + urea [RN:R00913]
Reaction(KEGG)
Substrate
3-guanidinopropanoate [CPD:C03065];
H2O [CPD:C00001]
Product
beta-alanine [CPD:C00099];
urea [CPD:C00086]
Comment
Requires Mn2+. Also acts, more slowly, on taurocyamine and 4-guanidinobutanoate.
History
EC 3.5.3.17 created 1989
Orthology
K18459  guanidinopropionase
Genes
GQU: AWC35_09795
ROR: RORB6_24330
RAO: DSD31_05870(speB)
KOR: AWR26_06155
KRD: A3780_17860
PAE: PA0288(gpuA)
PAEV: N297_294(speB)
PAEI: N296_294(speB)
PAU: PA14_03770(speB1)
PAP: PSPA7_0379(speB2)
PAG: PLES_02841(gpuA)
PAF: PAM18_0283(gpuA)
PNC: NCGM2_0323(speB1)
PAEB: NCGM1900_0284(speB1)
PAEP: PA1S_01445
PAEM: U769_01475
PAEL: T223_01435
PAEU: BN889_00343(gpuA)
PAEG: AI22_02460
PAEC: M802_293(speB)
PAEO: M801_294(speB)
PRE: PCA10_22720(gbuA)
PCQ: PcP3B5_01170(gbh_1)
PFL: PFL_0325(gpuA)
PPRC: PFLCHA0_c03300(gbh1)
PPRO: PPC_0336(gpuA)
PSEM: TO66_23435
PSET: THL1_2244
GAI: IMCC3135_16295(gpuA_1) IMCC3135_23280(gpuA_2)
HAM: HALO0709
HHH: CLM76_07845(speB)
BCEN: DM39_1662(speB)
BUL: BW21_4532(speB)
BPH: Bphy_6083
PHS: C2L64_39545(speB)
PTER: C2L65_36830(speB)
PPNO: DA70_00350
BHZ: ACR54_02441(gbh)
ACOM: CEW83_15355(speB)
BBAT: Bdt_3350(speB)
BBW: BDW_12730
BBAC: EP01_02370
BEX: A11Q_500
AVI: Avi_1009(speB)
RHL: LPU83_pLPU83c0428(gpuA)
SHZ: shn_29260
SNO: Snov_2246
MEX: Mext_3924
MDI: METDI4914
MCH: Mchl_4292
MPO: Mpop_4397
MET: M446_6964
MNO: Mnod_7678
META: Y590_19515
METD: C0214_21630(speB)
HDI: HDIA_3294(gbh)
SIL: SPOA0235(speB-4)
RCP: RCAP_rcc02271(speB2)
JAN: Jann_1967
PDE: Pden_5116
PGD: Gal_00165
MALG: MALG_03124
YPAC: CEW88_01780(speB)
RMM: ROSMUCSMR3_02397(gpuA)
LVS: LOKVESSMR4R_03207(gpuA)
SAGU: CDO87_08930(speB)
TMO: TMO_c0500
TXI: TH3_07450
TII: DY252_10375(speB)
PGV: SL003B_1579(speB-4)
SACI: Sinac_4136
 » show all
Taxonomy
Reference
1
  Authors
Yorifuji, T., Sugai, I., Matsumoto, H. and Tabuchi, A.
  Title
Characterization of 3-guanidinopropionate amidinohydrolase from Pseudomonas aeruginosa and a comparative study with 4-guanidinobutyrate amidinohydrolase from another Pseudomonas.
  Journal
Agric Biol Chem 46:1361-1363 (1982)
Other DBs
ExplorEnz - The Enzyme Database: 3.5.3.17
IUBMB Enzyme Nomenclature: 3.5.3.17
ExPASy - ENZYME nomenclature database: 3.5.3.17
BRENDA, the Enzyme Database: 3.5.3.17
CAS: 68821-77-2

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