KEGG ENZYME: 3.6.1.57

ENZYME: 3.6.1.57

Entry

EC 3.6.1.57                 Enzyme

Name

UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase;
PseG;
UDP-6-deoxy-AltdiNAc hydrolase;
Cj1312;
UDP-2,4-bis(acetamido)-2,4,6-trideoxy-beta-L-altropyranose hydrolase

Class

Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides

Sysname

UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase

Reaction(IUBMB)

UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose + H2O = 2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose + UDP [RN:R09834]

Reaction(KEGG)

R09834

Substrate

UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose;
H2O [CPD:C00001]

Product

2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose;
UDP [CPD:C00015]

Comment

The enzyme is involved in biosynthesis of pseudaminic acid.

History

EC 3.6.1.57 created 2011

Pathway

ec00520

Amino sugar and nucleotide sugar metabolism

ec00541

O-Antigen nucleotide sugar biosynthesis

ec01100

Metabolic pathways

Orthology

K15897

UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase

Genes

PWA:	Pecwa_3029

PEC:

W5S_3017

PRQ:	CYG50_16675(pseG)

VCT:	JV59_38535

VEU:	IXK98_09395(pseG)

VBR:	A6E01_00905

VSC:	VSVS12_00348

VAQ:	FIV01_00120(pseG)

VNV:	IF132_14095(pseG)

VFM:	VFMJ11_0174

PPR:	PBPRA2708(FLMD)

SALY:

E8E00_04315(pseG)

PMK:

MDS_1969

PPW:	PputW619_3708

PFE:	PSF113_1549

PMAN:

OU5_5136

PKR:	AYO71_10505

PBC:	CD58_08195 CD58_08730

PPUU:

PputUW4_03892

PSV:	PVLB_17275

PALL:

UYA_15080

PGG:	FX982_04817

PBZ:	GN234_09900(pseG)

PATA:

JWU58_20030(pseG)

PZE:	HU754_009160(pseG)

PMOE:

HV782_008630(pseG)

PTZ:	HU718_008850(pseG)

PHV:	HU739_009995(pseG)

PIE:	HU724_008285(pseG)

PSA:

PST_3837

PSH:	Psest_1813

MHC:	MARHY2543(rkpO)

MAD:

HP15_2395

MSX:	AU14_13730

MARI:

ACP86_02205

MSQ:	BKP64_02450

KAK:	Kalk_15495(pseG)

PAR:

Psyc_0657

PSPG:

AK823_00655

ABC:	ACICU_00078

ABX:

ABK1_0089

ADV:	DJ533_18115(pseG)

SDN:

Sden_1283

SPC:	Sputcn32_2626

SHN:	Shewana3_1308

SHW:	Sputw3181_1381

SJA:	SJ2017_2984

SBJ:	CF168_14345(pseG)

SAES:

HBH39_05120(pseG)

SLIT:

JQC75_11615(pseG)

CPS:

CPS_2095

COV:	EKO29_16595(pseG)

LSD:	EMK97_05525(pseG)

PSM:

PSM_A2269

PIA:	PI2015_2210

PPHE:

PP2015_927

PBW:	D172_015305

PALN:

B0W48_12435

PAGA:

PAGA_a1089

PCAR:

PC2016_0444

PVB:	J5X90_11680

AMH:	I633_05500

AMAA:

amad1_05160

AMAL:

I607_05010

AMAE:

I876_05305

AMAO:

I634_05330

AMAD:

I636_05165

AMAI:

I635_05135

AMAG:

I533_04910

AMAC:

MASE_04800

AMB:	AMBAS45_05035

AMG:	AMEC673_04865

AMK:	AMBLS11_04915

ALT:	ambt_13335

AAL:	EP13_05090

AAUS:

EP12_05115

ASP:	AOR13_2469

ASQ:	AVL57_11020

AAW:	AVL56_10160

ALR:	DS731_06390(pseG)

ALE:	AV939_10040

ALZ:	AV940_09810

SALM:

D0Y50_04690(pseG)

GAG:	Glaag_1259

GNI:

GNIT_2388

PMES:

FX988_03838

PAT:

Patl_3075

CATE:

C2869_15760(pseG)

PSY:	PCNPT3_05230

MVS:	MVIS_3751(flmD)

MYA:	MORIYA_3704(flmD)

MMAA:

FR932_21320(pseG)

MAGA:

Mag101_07545

LPM:	LP6_0750(pseG)

LPE:

lp12_0780

MAH:	MEALZ_0733

MEIN:

methR_P0376

FPZ:

LA55_1643

FAD:	CDH04_02730(pseG)

FMI:	F0R74_04815(pseG)

PSAL:

PSLF89_939

TZO:	THMIRHAT_08330(rkpO)

NHL:

Nhal_0398

RHH:	E0Z06_10255(pseG)

AEH:

Mlg_2325

TVR:

TVD_05115

HAM:

HALO0901

HTT:	HZS52_09360(pseG)

HCAM:

I4484_11780(pseG)

KUS:	B9G99_01675

PAUR:

FGL86_11225(pseG) FGL86_13915(pseG)

MME:	Marme_0616

MPC:	Mar181_2780

MPRI:

MP3633_0773(pseG)

MARD:

IBG28_15625

MFOI:

JSY38_13750(pseG)

NIK:	F5I99_05150(pseG)

RFO:	REIFOR_01453

AHA:

AHA_4179

AHD:	AI20_20160

AHH:	RY45_21695

ASA:	ASA_0149(flmD)

AEO:	O23A_p3840

ASR:	WL1483_1145

ADH:	CK627_03150(pseG)

AEL:	NCTC12917_01566

AALL:

I6G90_07890(pseG)

AJD:	I6H43_02540(pseG)

AEJ:	E5E97_03610(pseG)

KGE:

TQ33_1402

FPP:	FPB0191_00884

THIN:

CRN91_03210(pseG)

KKI:	KKKWG1_1880

AFF:	H3L97_09935(pseG)

CSTE:

H3L98_05390(pseG)

CRZ:	D1345_18310(pseG)

CHAE:

CH06BL_37220(rkpO)

DEE:	HQN60_14865(pseG)

RPF:	Rpic12D_0585

CBW:	RR42_m3216

BPT:	Bpet2305(murG2)

BTRM:

SAMEA390648700507(murG2)

BGM:	CAL15_06535

AXO:	NH44784_023741

POS:	DT070_03625(pseG)

POO:	F7R28_05815(pseG)

CTES:

O987_16655

HYR:	BSY239_4273

PBH:	AAW51_0138

PKT:	AT984_09215

HAR:

HEAR1124

JAB:	VN23_03240

JAZ:	YQ44_03300

HEE:	hmeg3_21290(pseG)

MASY:

DPH57_21460(pseG)

MASZ:

C9I28_00210(pseG)

MALI:

EYF70_30290(pseG)

MEU:	ACJ67_08705

FKU:	FGKAn22_23480(rkpO)

DSU:

Dsui_0080

NIV:	JY500_12340(pseG)

DAR:

Daro_1246

TCL:

Tchl_0898

AZQ:	G3580_04550(pseG)

SMI:	BN406_06053(rkpO)

RHI:	NGR_b09480(rkpO)

SFH:	SFHH103_06316(rkpO)

SINO:

SS05631_b61680

RGR:	FZ934_17435(pseG)

ABAW:

D5400_05880(pseG)

BJU:	BJ6T_37050

BJP:	RN69_17970

RBM:

TEF_03790

CAK:

Caul_4299

CHQ:	AQ619_13980

CFH:	C1707_01325(pseG)

CMAR:

IMCC12053_2935

MMR:	Mmar10_1967

SPHT:

K426_25895

ERF:	FIU90_06520(pseG)

MAGX:

XM1_4681

MAGN:

WV31_02415

MAG:

amb0714

HPY:

HP_0326

HEO:	C694_01650

HPA:	HPAG1_0330

HPS:	HPSH_01695

HHP:	HPSH112_01930

HHQ:	HPSH169_01815

HHR:	HPSH417_01635

HPG:	HPG27_308(neuA-2)

HPP:	HPP12_0324

HPL:	HPB8_1237(neuA1)

HPC:	HPPC_01655

HCA:	HPPC18_01650

HPM:	HPSJM_01750

HPE:	HPELS_05115

HPO:	HMPREF4655_20569

HPI:	hp908_0342

HPQ:	hp2017_03342(neuA2)

HPW:	hp2018_03362(neuA2)

HPU:	HPCU_01960

HEF:	HPF16_0334(neuA-2)

HPF:	HPF30_0969(neuA-2)

HEQ:	HPF32_0978(neuA-2)

HEX:	HPF57_0379(neuA-2)

HPT:	HPSAT_01630

HPZ:

HPKB_0334

HPV:	HPV225_0345

HPX:	HMPREF0462_0384

HEN:	HPSNT_01810

HPH:	HPLT_01675

HEG:	HPGAM_01815

HPN:	HPIN_01490

HEP:	HPPN120_01660

HEU:	HPPN135_01670

HES:	HPSA_01660

HPYS:

HPSA20_0362

HCN:	HPB14_01605

HEY:

MWE_0407

HER:	C695_01650

HEI:	C730_01650

HPYA:

HPAKL117_01615

HPYK:

HPAKL86_03495

HPYO:

HPOK113_0334(neuA)

HPYL:

HPOK310_0331

HPYB:

HPOKI102_01945

HPYC:

HPOKI112_01930

HPYD:

HPOKI128_01745

HPYE:

HPOKI154_01760

HPYF:

HPOKI422_01935

HPYG:

HPOKI673_01750

HPYH:

HPOKI828_01745

HPYJ:

HPOKI898_01945

HPYR:

K747_10305

HPYI:

K750_03220

HPYU:

K751_05815

HPYM:

K749_04020

HEM:	K748_02445

HEB:

U063_0668

HEZ:

U064_0670

HAC:	Hac_0994(neuA_fragment_2)

HMS:	HMU11720(flmD)

HFE:	HFELIS_15230(flmD)

HBI:	HBZC1_10950

HCE:

HCW_06085

HCM:

HCD_02155

HHM:	BN341_3120

HAD:	CDV25_01895

HET:	BBW65_02935

HCL:	NCTC13205_00367

HWI:	A0Z60_03730

WSU:

WS2107

SUA:

Saut_0140

SKU:	Sulku_0153

SULR:

B649_00700

CJE:	Cj1312(pseG)

CJB:	BN148_1312(pseG)

CJJ:	CJJ81176_1329

CJU:

C8J_1245

CJN:	ICDCCJ07001_1258

CJI:	CJSA_1250(pseG)

CJM:	CJM1_1284(pseG)

CJS:	CJS3_1412(pseG)

CJP:	A911_06380

CJEJ:

N564_01330

CJEU:

N565_01369

CJEN:

N755_01365

CJEI:

N135_01401

CJER:

H730_07500

CJV:	MTVDSCj20_1307(pseG)

CJY:	QZ67_01447(pseG)

CJQ:	UC78_1261(pseG)

CJL:	PJ17_06950

CJW:	PJ18_06755

CJR:

CJE1507

CJD:	JJD26997_0402

CJZ:	M635_02250

CJX:	BN867_13010

CCV:	CCV52592_0563(pseG)

CLA:	CLA_1320(pseG)

CLR:	UPTC16701_1294(pseG)

CLM:	UPTC16712_1316(pseG)

CLQ:	UPTC4110_1300(pseG)

CLN:	UPTC3659_1536(pseG)

CLL:	CONCH_1275(pseG)

CCOL:

BN865_08260c

CCC:	G157_02245

CCQ:	N149_1275(pseG)

CCF:

YSQ_02285

CCY:

YSS_07130

CCOI:

YSU_02300

CCOF:

VC76_06600(pseG)

CCOO:

ATE51_00940(pseG)

CAJ:	CIG1485E_1502(pseG)

CIS:	CINS_1276(pseG)

CVO:	CVOL_1307(pseG)

CPEL:

CPEL_1426(pseG)

CAMR:

CAQ16704_1326(pseG)

CSM:	CSUB8521_1503(pseG)

CSF:	CSUB8523_1599(pseG)

CHYO:

CHH_1596(pseG)

CHV:	CHELV3228_1546(pseG)

CPIN:

CPIN18020_0093(pseG)

CCUN:

CCUN_1344(pseG)

CAVI:

CAV_1214(pseG)

COJ:	CORN_1397(pseG)

CUX:	CUP3940_0287(pseG)

CRX:	CRECT_0230(pseG)

CARM:

CARM_1351(pseG)

CSHO:

CSHOW_1835(pseG)

CNV:	CNZW441b_1305(pseG)

CVU:	CVULP_1345(pseG)

SDL:

Sdel_2211

SBA:	Sulba_2445

SMUL:

SMUL_3175(pseG)

SHAL:

SHALO_2910

SULS:

Sdiek1_2899

SULJ:

SJPD1_2795

SULT:

FA592_06775(pseG)

ABL:	A7H1H_2192(pseG)

ACRE:

ACRYA_0126(pseG)

ALAN:

ALANTH_2130(pseG)

AFC:	AFAEC_0082(pseG)

ATHR:

ATH_1861(pseG)

ANT:	Arnit_2949

AAQI:

AAQM_2373(pseG)

AVP:	AVENP_2941(pseG)

APOC:

APORC_1983(pseG)

AROS:

NJU99_14130(pseG)

AMAR:

AMRN_2664(pseG)

ACAA:

ACAN_2668(pseG)

AMOL:

AMOL_2616(pseG)

AANA:

AANAER_2794(pseG)

HYO:

NNO_0333

HTM:	RZR91_12650(pseG)

SINU:

IMZ28_03845(pseG)

NAM:

NAMH_1602

NAP:	C3L23_08295

CMED:

FE773_01435(pseG)

CPAF:

C6V80_08995

HMR:	Hipma_1641

DAV:	DESACE_04230

GEB:

GM18_0651

GBN:	GEOBRER4_36340(rkpO)

DSA:	Desal_3633

DSX:	GD604_01470(pseG)

DAL:

Dalk_0630

DAT:	HRM2_36730(murG2)

DMM:	dnm_039410(pseG)

DTI:	Desti_2823

TID:	Thein_0448

BMX:

BMS_0364

BAE:	BATR1942_16230

BMOJ:

HC660_35580(spsG)

BTEQ:

G4P54_18825(pseG)

BIQ:	AN935_18465

BCG:	BCG9842_B1722(pseG)

BTM:

MC28_G041

BTI:

BTG_02020

BTN:	BTF1_14870

BTHT:

H175_328p076

BMYO:

BG05_5625

BMYC:

DJ92_3825

BSM:	BSM4216_3287

GST:	HW35_07460

BCO:	Bcell_3606

BCIR:

C2I06_13925(pseG)

PARH:

I5S86_21260(pseG)

BDA:	FSZ17_19140(pseG)

GTK:	GT3570_15230

GTM:	GT3921_03495

BCAL:

CWI35_12315(pseG)

GYC:	GYMC61_3209

GYA:	GYMC52_3238

GMC:	GY4MC1_0356

GGH:	GHH_c31960

GEA:	GARCT_03168(pseG)

GSE:	GT50_07440

PTL:	AOT13_01060

PTB:	DER53_12265(pseG)

AGN:	AFK25_13190

ACAI:

ISX45_14090(pseG)

LYB:	C3943_04200(pseG)

LYG:	C1N55_04760(pseG)

HHD:	HBHAL_1438

HLI:	HLI_07890(pseG)

PPSR:

I6J18_08560(pseG)

PSYH:

D0S48_07145(pseG)

GRC:	GI584_14705(pseG)

SEDD:

ERJ70_14405(pseG)

EXM:	U719_13430

PGM:	PGRAT_01325

POW:	IJ21_06680

PKB:	B4V02_02295

PPSC:

EHS13_05290(pseG)

PALB:

EJC50_01540(pseG)

TCO:	Theco_0167

COH:	EAV92_15270(pseG)

SSIL:

SOLI23_02140

JEO:

JMA_28180

KUR:	ASO14_2415

SPOS:

DV702_01270(pseG)

VIJ:	JNUCC6_18330(pseG)

AVS:	AWM76_07160

JEP:	BW721_08305

CNO:	NT01CX_1890

CBE:

Cbei_4277

CBZ:

Cbs_4277

CSR:	Cspa_c45300(pseG)

CLT:	CM240_1655

CFM:	BJL90_07040

CARG:

RSJ17_12840

CTH:

Cthe_2222

CTX:	Clo1313_2895

CCL:	Clocl_4079

HSC:	HVS_04510(pseG2)

DOR:	Desor_4903

DAI:	Desaci_3841

DAU:

Daud_1777

ACAE:

HYG86_00785

BPB:

bpr_I2558

CEW:	EKH84_21380(pseG)

AOE:

Clos_2509

GFE:	Gferi_06940

TMT:	Tmath_0719

KME:	H0A61_02801(pseG)

KPAR:

JL105_08010(pseG)

CAZO:

G3A45_09440(pseG)

SSG:	Selsp_0058

SELE:

ADJ74_06635

SELT:

BCS37_02255

PFT:

JBW_00745

ACIT:

HPK19_05680(pseG)

DSL:	Dacsa_2199

SLW:	BRW62_01490

PSEU:

Pse7367_1391

SYV:	AWQ23_02240

LEP:	Lepto7376_0081

OXY:	HCG48_23075(pseG)

AWA:	AA650_04365

CALO:

Cal7507_5343

RCA:

Rcas_0775

LIS:

LIL_12297

LBI:	LEPBI_I2032

LBF:

LBF_1979

LMAY:

DPV73_15865

FCI:	I6I83_02435

AMO:	Anamo_0536

BFG:	BF638R_3763

BHL:	Bache_1943

BHF:	C3V43_13560(pseG)

PET:	PEIBARAKI_4459

PARC:

CI960_11575

OSP:	Odosp_0122

PHE:

Phep_3944

CHU:

CHU_2760

SLI:

Slin_4265

SMON:

AWR27_16270

SPIR:

CWM47_05765(pseG)

SPIK:

EXU85_25855(pseG)

SPIB:

G8759_29010(pseG)

STAE:

HNV11_17750(pseG)

RHOZ:

GXP67_20315(pseG)

FAE:

FAES_1130

FIB:	A6C57_10710

FLI:	Fleli_3535

HYJ:	FHG12_00190(pseG)

PKO:	PKOR_19550

PACT:

CA264_07965

RUF:	TH63_02735

ASWU:

HUW51_16220(pseG)

CHK:	D4L85_11195

GFO:

GFO_2022

FPAL:

HYN49_00325(pseG)

FMG:	HYN48_00300(pseG)

WIJ:	BWZ20_09280

FOR:	FORMB_12910

FOH:	FORMA_12190

TAJ:	C1A40_06895(pseG)

FBU:	UJ101_00318

MRO:

MROS_1159

HTE:	Hydth_1339

DAP:	Dacet_0425

GTL:	EP073_12680

CNI:	Calni_0714

NLI:	G3M70_09865(pseG)

MOX:

DAMO_1787

METF:

CFE53_01735

MSI:

Msm_1538

METV:

K4897_08540

MCUB:

MCBB_1286

HAGS:

JT689_05590(pseG)

HRR:	HZS55_05700(pseG)

HWC:

Hqrw_3373

HXA:	Halxa_2364

HALY:

HYG82_08530(pseG)

PSYT:

DSAG12_01853

» show all

Reference

1 [PMID:16728396]

Authors

Liu F, Tanner ME

Title

PseG of pseudaminic acid biosynthesis: a UDP-sugar hydrolase as a masked glycosyltransferase.

Journal

J Biol Chem 281:20902-9 (2006)
DOI:10.1074/jbc.M602972200

Sequence

[cje:Cj1312]

Reference

2 [PMID:16751642]

Authors

Schoenhofen IC, McNally DJ, Brisson JR, Logan SM

Title

Elucidation of the CMP-pseudaminic acid pathway in Helicobacter pylori: synthesis from UDP-N-acetylglucosamine by a single enzymatic reaction.

Journal

Glycobiology 16:8C-14C (2006)
DOI:10.1093/glycob/cwl010

Sequence

[hpy:HP_0326]

Other DBs

ExplorEnz - The Enzyme Database:

3.6.1.57

IUBMB Enzyme Nomenclature:

3.6.1.57

ExPASy - ENZYME nomenclature database:

3.6.1.57

BRENDA, the Enzyme Database:

3.6.1.57

DBGET integrated database retrieval system