KEGG   ENZYME: 3.6.3.24Help
Entry
EC 3.6.3.24                 Enzyme                                 

Name
nickel-transporting ATPase
Class
Hydrolases;
Acting on acid anhydrides;
Acting on acid anhydrides to catalyse transmembrane movement of substances
BRITE hierarchy
Sysname
ATP phosphohydrolase (nickel-importing)
Reaction(IUBMB)
ATP + H2O + Ni2+out = ADP + phosphate + Ni2+in
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
Ni2+ [CPD:C19609]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
Ni2+ [CPD:C19609]
Comment
ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. A bacterial enzyme that imports Ni2+.
History
EC 3.6.3.24 created 2000
Orthology
K10824  nickel transport system ATP-binding protein
K15587  nickel transport system ATP-binding protein
Genes
ECO: b3479(nikD) b3480(nikE)
ECJ: JW3444(nikD) JW3445(nikE)
ECD: ECDH10B_3653(nikD) ECDH10B_3654(nikE)
EBW: BWG_3170(nikD) BWG_3171(nikE)
ECOK: ECMDS42_2918(nikD) ECMDS42_2919(nikE)
ECE: Z4871(nikD) Z4872(nikE)
ECS: ECs4346(nikD) ECs4347(nikE)
ECF: ECH74115_4819(nikD) ECH74115_4820(nikE)
ETW: ECSP_4453(nikD) ECSP_4454(nikE)
ELX: CDCO157_4083(nikD) CDCO157_4084(nikE)
EOJ: ECO26_4566(nikD) ECO26_4567(nikE)
EOI: ECO111_4287(nikD) ECO111_4288(nikE)
EOH: ECO103_4199(nikD) ECO103_4200(nikE)
ECOO: ECRM13514_4452(nikD) ECRM13514_4453(nikE)
ECOH: ECRM13516_4250(nikD) ECRM13516_4251(nikE)
ECG: E2348C_3720(nikD) E2348C_3721(nikE)
EOK: G2583_4200(nikD) G2583_4201(nikE)
ESO: O3O_23985(nikD) O3O_23990(nikE)
ESM: O3M_01700(nikE) O3M_01705(nikD)
ESL: O3K_01655(nikE) O3K_01660(nikD)
ECW: EcE24377A_3963(nikD) EcE24377A_3964(nikE)
EUN: UMNK88_4249(nikD) UMNK88_4250(nikE)
ECC: c4272(nikD) c4273(nikE)
ECI: UTI89_C3996(nikD) UTI89_C3997(nikE)
ECV: APECO1_2974(nikE) APECO1_2975(nikD)
ECX: EcHS_A3678(nikD) EcHS_A3679(nikE)
ECM: EcSMS35_3763(nikD) EcSMS35_3764(nikE)
ECR: ECIAI1_3626(nikD) ECIAI1_3627(nikE)
ECQ: ECED1_4152(nikD) ECED1_4153(nikE)
ECK: EC55989_3887(nikD) EC55989_3888(nikE)
ECT: ECIAI39_3960(nikD) ECIAI39_3961(nikE)
EOC: CE10_4003(nikD) CE10_4004(nikE)
EUM: ECUMN_3960(nikD) ECUMN_3961(nikE)
ECZ: ECS88_3882(nikD) ECS88_3883(nikE)
ELO: EC042_3759(nikD) EC042_3760(nikE)
ELN: NRG857_17250(nikD) NRG857_17255(nikE)
EBR: ECB_03328(nikD) ECB_03329(nikE)
EKF: KO11_05370(nikE) KO11_05375(nikD)
EAB: ECABU_c39090(nikD) ECABU_c39100(nikE)
EIH: ECOK1_3908(nikD) ECOK1_3909(nikE)
ENA: ECNA114_3588(nikD) ECNA114_3589(nikE)
ELU: UM146_17520(nikD) UM146_17525(nikE)
ELW: ECW_m3741(nikD) ECW_m3742(nikE)
ELL: WFL_18270(nikD) WFL_18275(nikE)
ELC: i14_3942(nikD) i14_3943(nikE)
ELD: i02_3942(nikD) i02_3943(nikE)
ELP: P12B_c3576(nikD) P12B_c3577(nikE)
EBL: ECD_03328(nikD) ECD_03329(nikE)
EBE: B21_03281(nikD) B21_03282(nikE)
ELF: LF82_1491(nikD) LF82_1492(nikE)
ECOI: ECOPMV1_03800(gsiA_7) ECOPMV1_03801(gsiA_8)
ECOS: EC958_3873(nikD) EC958_3874(nikE)
EAL: EAKF1_ch2474c(nikE) EAKF1_ch2475c(nikD)
EMA: C1192_15330(nikD) C1192_15335(nikE)
SFL: SF3497(nikD) SF3498(nikE)
SFX: S4265(nikE) S4266(nikD)
SFV: SFV_3482(nikD) SFV_3483(nikE)
SFE: SFxv_3813(nikD) SFxv_3814(nikE)
SFT: NCTC1_03779(nikD) NCTC1_03780(nikE)
SSN: SSON_3717(nikD) SSON_3718(nikE)
SBO: SBO_3476(nikD) SBO_3477(nikE)
SBC: SbBS512_E3841(nikE) SbBS512_E3842(nikD)
SDY: SDY_3634(nikD) SDY_3635(nikE)
SHQ: A0259_21155(nikD) A0259_21160(nikE)
ENR: H650_13785(nikD) H650_13790(nikE)
ENF: AKI40_0299(nikE) AKI40_0300(nikD)
KPN: KPN_03853(nikD) KPN_03854(nikE)
KPU: KP1_5192(nikD) KP1_5193(nikE)
KPH: KPNIH24_24960(nikD) KPNIH24_24965(nikE)
KPZ: KPNIH27_23880(nikD) KPNIH27_23885(nikE)
KPV: KPNIH29_24800(nikD) KPNIH29_24805(nikE)
KPW: KPNIH30_25250(nikD) KPNIH30_25255(nikE)
KPY: KPNIH31_24305(nikD) KPNIH31_24310(nikE)
KPG: KPNIH32_26120(nikD) KPNIH32_26125(nikE)
KPC: KPNIH10_24925(nikD) KPNIH10_24930(nikE)
KPQ: KPR0928_24445(nikD) KPR0928_24450(nikE)
KPT: VK055_3616(nikE3) VK055_3617
KPE: KPK_0259(nikE) KPK_0260(nikD)
KPO: KPN2242_22275(nikD) KPN2242_22280(nikE)
KPR: KPR_5063
KPX: PMK1_01355(nikD) PMK1_01356(nikE)
KPB: FH42_15600(nikD) FH42_15605(nikE)
KPNE: KU54_001340(nikE) KU54_001345(nikD)
KPNU: LI86_01335(nikE) LI86_01340(nikD)
KPNK: BN49_0263(nikE) BN49_0264(nikD)
KPK: A593_09470(nikD) A593_09475(nikE)
KOX: KOX_05120(nikD) KOX_05125(nikE)
KOY: J415_04630(nikE) J415_04635(nikD)
KOM: HR38_03600(nikD) HR38_03605(nikE)
KOK: KONIH1_27650(nikD) KONIH1_27655(nikE)
KOC: AB185_08740(nikE) AB185_08745(nikD)
EAE: EAE_05730(nikD) EAE_05735(nikE)
KQV: B8P98_01355(nikE) B8P98_01360(nikD)
CRO: ROD_43171(nikE) ROD_43181(nikD)
CAMA: F384_18955(nikD) F384_18960(nikE)
CAF: AL524_01620(nikD) AL524_01625(nikE)
CFAR: CI104_01230(nikD)
CIR: C2U53_08205(nikD) C2U53_08210(nikE)
EBT: EBL_c18430(nikD) EBL_c18440(nikE)
ROR: RORB6_20080(nikE) RORB6_20085(nikD)
RON: TE10_00910(nikD) TE10_00915(nikE)
RAO: DSD31_01415(nikE) DSD31_01420(nikD)
PGE: LG71_23340(nikE) LG71_23345(nikD)
KLE: AO703_09095(nikE) AO703_09100(nikD)
KOR: AWR26_01270(nikE) AWR26_01275(nikD)
KRD: A3780_23460(nikD) A3780_23465(nikE)
LEW: DAI21_16615(nikE) DAI21_16620(nikD)
EBC: C2U52_09820(nikE) C2U52_09825(nikD)
ETR: ETAE_1375(nikE) ETAE_1376(nikD)
ETD: ETAF_1278(nikE) ETAF_1279(nikD)
ETE: ETEE_3364(nikE) ETEE_3365(nikD)
ETC: ETAC_06500(nikE) ETAC_06505(nikD)
EDW: QY76_13060(nikD) QY76_13065(nikE)
EDL: AAZ33_07155(nikE) AAZ33_07160(nikD)
KIN: AB182_26985(nikE) AB182_26990(nikD)
MSU: MS0462(oppF) MS0463(dppD)
PPU: PP_3345(nikD) PP_3346(nikE)
PFZ: AV641_09925(nikE) AV641_09930(nikD)
PLQ: AA042_21065(nikD) AA042_21070(nikE)
PPSY: AOC04_06810(nikE) AOC04_06815(nikD)
HHE: HH_0414(nikE) HH_0415(nikD)
HCP: HCN_0693(nikE)
HCB: HCBAA847_1296(nikE) HCBAA847_1297(nikCD)
WSU: WS0977(dppF) WS0978(OPP-1D) WS0987(OPP-1D) WS0988
DDS: Ddes_1029
DMA: DMR_12000(nikE) DMR_12010(nikD)
AVI: Avi_7617(nikD) Avi_7618(nikE)
BMEL: DK63_2751(nikE) DK63_2752(nikD)
BMI: BMEA_B0779(nikE) BMEA_B0780(nikD)
BMZ: BM28_B0769(nikE) BM28_B0770(nikD)
BMG: BM590_B0767(nikE) BM590_B0768(nikD)
BMEE: DK62_2647(nikD) DK62_2648(nikE)
BMB: BruAb2_0431(nikD) BruAb2_0432(nikE)
BABO: DK55_2425(nikD) DK55_2426(nikE)
BABR: DO74_2840(nikD) DO74_2841(nikE)
BABT: DK49_2813(nikE) DK49_2814(nikD)
BABB: DK48_2265(nikE) DK48_2266(nikD)
BABU: DK53_2428(nikD) DK53_2429(nikE)
BABS: DK51_3010(nikD) DK51_3011(nikE)
BABC: DO78_2629(nikE) DO78_2630(nikD)
BMS: BRA0800(nikE) BRA0801(nikD)
BSI: BS1330_II0793(nikE) BS1330_II0794(nikD)
BSF: BSS2_II0759(nikE) BSS2_II0760(nikD)
BSUI: BSSP1_II0741(nikE) BSSP1_II0742(nikD)
BSUP: BSPT1_II0739(nikE) BSPT1_II0740(nikD)
BSUV: BSPT2_II0741(nikE) BSPT2_II0742(nikD)
BSUC: BSSP2_II0752(nikE) BSSP2_II0753(nikD)
BMT: BSUIS_B0792(nikE) BSUIS_B0793(nikD)
BSZ: DK67_2757(nikE) DK67_2758(nikD)
BSV: BSVBI22_B0792(nikE) BSVBI22_B0793(nikD)
BSW: IY71_15010(nikE) IY71_15015(nikD)
BSG: IY72_14965(nikE) IY72_14970(nikD)
BOV: BOV_A0750(nikE)
BCS: BCAN_B0814(nikE) BCAN_B0815(nikD)
BOL: BCOUA_II0800(nikE) BCOUA_II0801(nikD)
BCAR: DK60_2493(nikE) DK60_2494(nikD)
BCAS: DA85_14300(nikE) DA85_14305(nikD)
BMR: BMI_II794(nikE) BMI_II795(nikD)
BPP: BPI_II856(nikE) BPI_II857(nikD)
BPV: DK65_2843(nikD) DK65_2844(nikE)
MAQU: Maq22A_c23670(dppF) Maq22A_c23675(dppD)
RSU: NHU_03949(nikD) NHU_03950(nikE)
RRU: Rru_A2273(nikE) Rru_A2274(nikD)
RRF: F11_11690(nikE) F11_11695(nikD)
ATI: AL072_10200(nikD) AL072_10205(nikE)
THAC: CSC3H3_23880(nikE) CSC3H3_23885(nikD)
BLI: BL02421(appDB) BL02422(appFB)
BLD: BLi02814(appD2) BLi02815(appF2)
BLH: BaLi_c29090(appD2) BaLi_c29100(appF2)
BMQ: BMQ_1718(nikD) BMQ_1719(nikE)
BMD: BMD_1705(nikD) BMD_1706(nikE)
BMEG: BG04_4027(nikD) BG04_4028(nikE)
BKW: BkAM31D_01695(oppD_2) BkAM31D_01700(oppF_2)
LSP: Bsph_2973(nikE) Bsph_2974(dppD)
SAU: SA2251(opp-1F) SA2252(opp-1D)
SAM: MW2387(opp-1F) MW2388(opp-1D)
SAR: SAR2550(opp-1F) SAR2551(opp-1D)
SAE: NWMN_2360(opp1F) NWMN_2361(opp1D)
SUJ: SAA6159_02360(opp-1F) SAA6159_02361(opp-1D)
SUK: SAA6008_02504(opp-1F) SAA6008_02505(opp-1D)
SUX: SAEMRSA15_23610(opp-1F) SAEMRSA15_23620(opp-1D)
SUW: SATW20_25910(opp-1F) SATW20_25920(opp-1D)
SUF: SARLGA251_22430(opp-1F) SARLGA251_22440(opp-1D)
SAUE: RSAU_002301(opp1F) RSAU_002302(opp1D)
SAUS: SA40_2211(opp-1F) SA40_2212(opp-1D)
SAUU: SA957_2295(opp-1F) SA957_2296(opp-1D)
SAUG: SA268_2368(opp-1F) SA268_2369(opp-1D)
SAUZ: SAZ172_2566(opp-1F) SAZ172_2567(opp-1D)
SAB: SAB2346c(opp1F) SAB2347c(opp1D)
SUY: SA2981_2400(opp-1F) SA2981_2401(opp-1D)
SAUB: C248_2513(opp-1F) C248_2514(opp-1D)
SLN: SLUG_01490(opp-1D) SLUG_01500(opp-1F)
SXO: SXYL_00074(nikD) SXYL_00075(nikE)
BLR: BRLA_c028600(nikE_1)
PPM: PPSC2_24670(nikE) PPSC2_24675(nikD)
PPO: PPM_4902(nikE) PPM_4903(nikD)
ASOC: CB4_02653(nikE) CB4_02655(oppD_1)
SAK: SAK_1538(nikE) SAK_1539(nikD)
SGC: A964_1421(nikE) A964_1422(nikD)
SAGL: GBS222_1255(nikE) GBS222_1256(nikD)
SSA: SSA_0503 SSA_0504(amiF)
SANC: SANR_1336
AWO: Awo_c00450(oppD4) Awo_c00460(oppF4)
LET: O77CONTIG1_00102(nikE)
TPED: TPE_2548(nikE) TPE_2549(nikC)
 » show all
Taxonomy
Reference
1  [PMID:7569321]
  Authors
Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH Jr.
  Title
Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases.
  Journal
Res Microbiol 146:271-8 (1995)
DOI:10.1016/0923-2508(96)81050-3
Reference
2  [PMID:9294450]
  Authors
Hendricks JK, Mobley HL.
  Title
Helicobacter pylori ABC transporter: effect of allelic exchange mutagenesis on urease activity.
  Journal
J Bacteriol 179:5892-902 (1997)
DOI:10.1128/JB.179.18.5892-5902.1997
Reference
3  [PMID:9889977]
  Authors
Saier MH Jr.
  Title
Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya.
  Journal
Adv Microb Physiol 40:81-136 (1998)
Reference
4
  Authors
Griffiths, J.K. and Sansom, C.E.
  Title
The Transporter Factsbook, Academic Press, San Diego, 1998.
Other DBs
ExplorEnz - The Enzyme Database: 3.6.3.24
IUBMB Enzyme Nomenclature: 3.6.3.24
ExPASy - ENZYME nomenclature database: 3.6.3.24
BRENDA, the Enzyme Database: 3.6.3.24

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