Entry |
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Name |
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Class |
Hydrolases;
Acting on carbon-carbon bonds;
In ketonic substances
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Sysname |
L-kynurenine hydrolase
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Reaction(IUBMB) |
L-kynurenine + H2O = anthranilate + L-alanine [RN: R00987]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
A pyridoxal-phosphate protein. Also acts on 3'-hydroxy-L-kynurenine and some other (3-arylcarbonyl)-alanines.
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History |
EC 3.7.1.3 created 1965
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Pathway |
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Orthology |
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Genes |
» show all
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Reference |
|
Authors |
JAKOBY WB, BONNER DM. |
Title |
Kynureninase from Neurospora: purification and properties. |
Journal |
J Biol Chem 205:699-707 (1953) |
Reference |
|
Authors |
JAKOBY WB, BONNER DM. |
Title |
Kynureninase from Neurospora: interaction of enzyme with substrates, coenzyme, and amines. |
Journal |
J Biol Chem 205:709-15 (1953) |
Reference |
|
Authors |
KNOX WE. |
Title |
The relation of liver kynureninase to tryptophan metabolism in pyridoxine deficiency. |
Journal |
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Reference |
4 |
Authors |
Wiss, O. and Weber, F. |
Title |
Die Reindarstellung der Kynureninase. |
Journal |
Hoppe-Seyler's Z Physiol Chem 304:232-240 (1956) |
Other DBs |
ExplorEnz - The Enzyme Database: | 3.7.1.3 |
ExPASy - ENZYME nomenclature database: | 3.7.1.3 |
BRENDA, the Enzyme Database: | 3.7.1.3 |
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