Entry |
|
Name |
uroporphyrinogen decarboxylase;
uroporphyrinogen III decarboxylase;
porphyrinogen carboxy-lyase;
porphyrinogen decarboxylase;
uroporphyrinogen-III carboxy-lyase
|
Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
 |
Sysname |
uroporphyrinogen-III carboxy-lyase (coproporphyrinogen-III-forming)
|
Reaction(IUBMB) |
uroporphyrinogen III = coproporphyrinogen III + 4 CO2 [RN: R03197]
|
Reaction(KEGG) |
|
Substrate |
uroporphyrinogen III [CPD: C01051]
|
Product |
|
Comment |
Acts on a number of porphyrinogens.
|
History |
EC 4.1.1.37 created 1965
|
Pathway |
ec00860 | Porphyrin and chlorophyll metabolism |
ec01110 | Biosynthesis of secondary metabolites |
|
Orthology |
K01599 | uroporphyrinogen decarboxylase |
|
Genes |
» show all
 |
Reference |
|
Authors |
MAUZERALL D, GRANICK S. |
Title |
Porphyrin biosynthesis in erythrocytes. III. Uroporphyrinogen and its decarboxylase. |
Journal |
J Biol Chem 232:1141-62 (1958) |
Reference |
|
Authors |
Tomio JM, Garcia RC, San Martin de Viale LC, Grinstein M. |
Title |
Porphyrin biosynthesis. VII. Porphyrinogen carboxy-lyase from avian erythrocytes. Purification and properties. |
Journal |
|
Other DBs |
ExplorEnz - The Enzyme Database: | 4.1.1.37 |
ExPASy - ENZYME nomenclature database: | 4.1.1.37 |
|