KEGG   ENZYME: 4.1.1.61Help
Entry
EC 4.1.1.61                 Enzyme                                 

Name
4-hydroxybenzoate decarboxylase;
p-hydroxybenzoate decarboxylase;
4-hydroxybenzoate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname
4-hydroxybenzoate carboxy-lyase (phenol-forming)
Reaction(IUBMB)
4-hydroxybenzoate = phenol + CO2 [RN:R01238]
Reaction(KEGG)
Substrate
4-hydroxybenzoate [CPD:C00156]
Product
phenol [CPD:C00146];
CO2 [CPD:C00011]
History
EC 4.1.1.61 created 1972
Pathway
ec00627  Aminobenzoate degradation
ec01120  Microbial metabolism in diverse environments
Orthology
K01612  vanillate/4-hydroxybenzoate decarboxylase subunit C
K16239  4-hydroxybenzoate decarboxylase subunit C
K21759  vanillate/4-hydroxybenzoate decarboxylase subunit D
Genes
ECE: Z4045 Z4046
ECS: ECs3591 ECs3592
ECF: ECH74115_3988(kpdD) ECH74115_3989(kpdC)
ETW: ECSP_3685 ECSP_3686
ELX: CDCO157_3351 CDCO157_3352
EOJ: ECO26_3806 ECO26_3807
EOI: ECO111_3461 ECO111_3462
EOH: ECO103_3279 ECO103_3280
ECOO: ECRM13514_3588 ECRM13514_3589
ECOH: ECRM13516_3454 ECRM13516_3455
EOK: G2583_3385(kpdD) G2583_3386(kpdC)
ECW: EcE24377A_3038(kpdD) EcE24377A_3039(kpdC)
ECM: EcSMS35_2862(kpdD) EcSMS35_2863(kpdC)
EOC: CE10_3162(kpdD) CE10_3163(kpdC)
ELO: EC042_2931(kpdD) EC042_2932(kpdC)
EAL: EAKF1_ch3256(kpdC) EAKF1_ch3257(kpdD)
STT: t2823 t2824
SEC: SCH_2852(vdcC) SCH_2853
SEH: SeHA_C3111(kpdC) SeHA_C3112(kpdD)
SHB: SU5_03401
SEE: SNSL254_A3127(kpdC) SNSL254_A3128(kpdD)
SEW: SeSA_A3072(kpdC) SeSA_A3073(kpdD)
SEA: SeAg_B3043(kpdC) SeAg_B3044(kpdD)
SED: SeD_A3231(kpdC) SeD_A3232(kpdD)
SET: SEN2761
SENB: BN855_29650(kpdC) BN855_29660(kpdD)
SFE: SFxv_3028
SFN: SFy_3930
SFS: SFyv_4007
SFT: NCTC1_03039(bsdC)
SDY: SDY_2936
EEC: EcWSU1_03555(bsdD) EcWSU1_03556(vdcC)
CTU: CTU_33060(bsdD) CTU_33070(vdcC)
KPT: VK055_4419(bsdC) VK055_4420(bsdD)
KPE: KPK_1026(kpdC) KPK_1027(kpdD)
KPX: PMK1_00577(bsdD) PMK1_00578(bsdC_1)
SPLY: Q5A_002535(bsdC) Q5A_002540(bsdD)
PAM: PANA_1620(vdcC) PANA_1621(kdpD)
PLF: PANA5342_2603(vdcC)
PAJ: PAJ_0971(vdcC) PAJ_0972(kdpD)
CYQ: Q91_0491
BCEN: DM39_6399
BCEW: DM40_5534
BPSL: WS57_16875
CGRA: CGRAC_0600
BSU: BSU03640(ubiD) BSU03651(bsdD)
BSR: I33_0416(ubiD) I33_0417
BSH: BSU6051_03640(ubiD) BSU6051_03651(bsdD)
BSUT: BSUB_00413(ubiD) BSUB_00414(bsdD)
BSUL: BSUA_00413(ubiD) BSUA_00414(bsdD)
BSS: BSUW23_01875(ubiD) BSUW23_01880(bsdD)
BST: GYO_0579(ubiD) GYO_0580
BSQ: B657_03640(ubiD) B657_03651(bsdD)
BSX: C663_0356(bsdC) C663_0357(bsdD)
BLI: BL01741(yclC)
BLD: BLi00427(bsdC) BLi00428(bsdD)
BLH: BaLi_c04390(bsdC) BaLi_c04400(bsdD)
BAY: RBAM_003810(yclC) RBAM_003820(yclD1)
BAQ: BACAU_0317(kpdC) BACAU_0318(bsdD)
BYA: BANAU_0318(yclC) BANAU_0319(yclD1)
BAML: BAM5036_0340(bsdC) BAM5036_0341(bsdD)
BAMA: RBAU_0354(bsdC) RBAU_0355(bsdD)
BAMN: BASU_0339(bsdC) BASU_0340(bsdD)
BAMY: V529_03400(yclC) V529_03410
BMP: NG74_00359(bsdC) NG74_00360(bsdD)
BAO: BAMF_0324(bsdC) BAMF_0325(bsdD)
BAZ: BAMTA208_01640(bsdC) BAMTA208_01645(bsdD)
BQL: LL3_00334(bsdC) LL3_00335
BXH: BAXH7_00337(yclC) BAXH7_00338(yclD1)
BQY: MUS_0341(kpdC) MUS_0342(kpdD)
BMQ: BMQ_2638 BMQ_2639(ubiD)
BMD: BMD_2625 BMD_2626(ubiD)
BMEG: BG04_5093(bsdD) BG04_5094(bsdC)
BACL: BS34A_04200(ubiD) BS34A_04210(bsdD)
BGY: BGLY_0441(bsdC) BGLY_0442(bsdD)
PPO: PPM_0383(yclC)
MSTE: MSTE_03756
SLE: sle_04250(sle_04250) sle_04260(sle_04260)
PSEH: XF36_22440
CTR: CT_085
CTD: CTDEC_0085(yigC)
CTF: CTDLC_0085(yigC)
CTA: CTA_0090
CTY: CTR_0841
CRA: CTO_0090
CTRQ: A363_00088
CTB: CTL0340
CTO: CTL2C_554
CTJ: JALI_0841
CTZ: CTB_0841
CSW: SW2_0861
CES: ESW3_0861
CTRB: BOUR_00087
CTEC: EC599_0881
CFS: FSW4_0861
CFW: FSW5_0861
CTFW: SWFP_0911
CTCH: O173_00460
CTRI: BN197_0861
CTRA: BN442_0861
CTCT: CTW3_00455
CMU: TC_0359
CMUR: Y015_01870
CMX: DNC_01795
CMZ: TAC_01870
CPN: CPn0328
CPA: CP_0429
CPJ: CPj0328(CPj0328)
CPT: CpB0338
CPM: G5S_0805
CPEC: CPE3_0439
CPEO: CPE1_0439
CPER: CPE2_0439
CHP: CPSIT_0493(ubiD)
CHB: G5O_0490
CHS: CPS0A_0500(ubiD)
CHI: CPS0B_0497(ubiD)
CHT: CPS0D_0499(ubiD)
CHC: CPS0C_0502(ubiD)
CHR: Cpsi_4461
CPSC: B711_0529
CPSN: B712_0498
CPSB: B595_0528
CPSG: B598_0500
CPSM: B602_0496
CPSI: B599_0493
CPSV: B600_0529
CPSW: B603_0504
CPST: B601_0500
CPSD: BN356_4501
CPSA: AO9_02385
CCA: CCA_00454
CAB: CAB440
CABO: AB7_4941
CFE: CF0553(oxr2)
HTI: HTIA_2316
 » show all
Taxonomy
Reference
1  [PMID:5309907]
  Authors
Grant DJ, Patel JC
  Title
The non-oxidative decarboxylation of p-hydroxybenzoic acid, gentisic acid, protocatechuic acid and gallic acid by Klebsiella aerogenes (Aerobacter aerogenes).
  Journal
Antonie Van Leeuwenhoek 35:325-43 (1969)
Reference
2
  Authors
Tschech, A. and Fuchs, G.
  Title
Anaerobic degradation of phenol via carboxylation to 4-hydroxybenzoate - in vitro study of isotope exchange between (CO2)-C-14 and 4-hydroxybenzoate.
  Journal
Arch Microbiol 152:594-599 (1989)
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.61
IUBMB Enzyme Nomenclature: 4.1.1.61
ExPASy - ENZYME nomenclature database: 4.1.1.61
UM-BBD (Biocatalysis/Biodegradation Database): 4.1.1.61
BRENDA, the Enzyme Database: 4.1.1.61
CAS: 37290-53-2

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