KEGG   ENZYME: 4.1.1.64Help
Entry
EC 4.1.1.64                 Enzyme                                 

Name
2,2-dialkylglycine decarboxylase (pyruvate);
dialkyl amino acid (pyruvate) decarboxylase;
alpha-dialkyl amino acid transaminase;
2,2-dialkyl-2-amino acid-pyruvate aminotransferase;
L-alanine-alpha-ketobutyrate aminotransferase;
dialkylamino-acid decarboxylase (pyruvate);
2,2-dialkylglycine carboxy-lyase (amino-transferring)
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname
2,2-dialkylglycine carboxy-lyase (amino-transferring; L-alanine-forming)
Reaction(IUBMB)
2,2-dialkylglycine + pyruvate = dialkyl ketone + CO2 + L-alanine [RN:R03854]
Reaction(KEGG)
Substrate
2,2-dialkylglycine [CPD:C02623];
pyruvate [CPD:C00022]
Product
dialkyl ketone [CPD:C02146];
CO2 [CPD:C00011];
L-alanine [CPD:C00041]
Comment
A pyridoxal-phosphate protein. Acts on 2-amino-2-methylpropanoate (i.e. 2-methylalanine), 2-amino-2-methylbutanoate and 1-aminocyclopentanecarboxylate.
History
EC 4.1.1.64 created 1972
Orthology
K00596  2,2-dialkylglycine decarboxylase (pyruvate)
Genes
HAA: A5892_06680 A5892_07480
BVI: Bcep1808_3365
BVE: AK36_3396(dgdA)
BUR: Bcep18194_B0665
BCN: Bcen_3362
BCH: Bcen2424_5005
BCM: Bcenmc03_5282
BCJ: BCAM2237
BCEN: DM39_5613(dgdA)
BCEW: DM40_4955(dgdA)
BCEO: I35_6128
BAM: Bamb_4418
BCT: GEM_3432
BCED: DM42_5757(dgdA)
BCON: NL30_01295
BLAT: WK25_27250
BTEI: WS51_08310
BSEM: WJ12_31120
BPSL: WS57_02965
BGO: BM43_6089(dgdA)
BUK: MYA_2984
BXE: Bxe_B2675
BXB: DR64_5009(dgdA)
BFN: OI25_5730(dgdA)
PPNO: DA70_03710
PPNM: LV28_02605
PPUL: RO07_21545
PSPU: NA29_15775
PAPI: SG18_20380
AXY: AXYL_05358(dgdA)
AXX: ERS451415_05181(dgdA_2)
MPT: Mpe_A1466
RGE: RGE_11320
SMD: Smed_5089
ATU: Atu5302
RIR: BN877_II1367(dgdA)
SHZ: shn_26760
MOR: MOC_3244
SPSE: SULPSESMR1_01214(dgdA)
RMM: ROSMUCSMR3_03320(dgdA)
SSAN: NX02_17365
GXL: H845_1622
TMO: TMO_1799(dgdA)
TXI: TH3_07410
LME: LEUM_0839
LMM: MI1_03880
LMK: LMES_0762
MVA: Mvan_5803
TPR: Tpau_3251
SCO: SCO7537(SC8G12.13c)
SLV: SLIV_01625(dgdA)
STRD: NI25_35870
SMAL: SMALA_0919
LMOI: VV02_24205
SERJ: SGUI_1980
SRO: Sros_5114
NML: Namu_5409
SEN: SACE_2647
AMD: AMED_0279
AMN: RAM_01410
AMM: AMES_0274
AMZ: B737_0275
AOI: AORI_6411
AJA: AJAP_06860(dgdA)
PDX: Psed_5588
PSEE: FRP1_10245
AMI: Amir_4825
KAL: KALB_5707
ACTI: UA75_05470
ACAD: UA74_05470
AHG: AHOG_05110(dgdA)
ACTN: L083_6648
AFS: AFR_23730
SNA: Snas_1896
BTP: D805_0368
 » show all
Taxonomy
Reference
1
  Authors
Bailey, G.B. and Dempsey, W.B.
  Title
Purification and properties of an alpha-dialkyl amino acid transaminase.
  Journal
Biochemistry 6:1526-1533 (1967)
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.64
IUBMB Enzyme Nomenclature: 4.1.1.64
ExPASy - ENZYME nomenclature database: 4.1.1.64
BRENDA, the Enzyme Database: 4.1.1.64
CAS: 9032-17-1

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